Evasion and interference: intracellular pathogens modulate caspase-dependent inflammatory responses

Innate Immune Pattern Recognition: A Cell Biological Perspective

(2015) Sky W. Brubaker et al.   Annual Review of Immunology

Cutting Edge: Inflammasome Activation in Primary Human Macrophages Is Dependent on Flagellin

(2015) Jens Kortmann et al.   JOURNAL OF IMMUNOLOGY

Salmonellae interactions with host processes

(2015) Doris L. LaRock et al.   NATURE REVIEWS MICROBIOLOGY

Response of host inflammasomes to viral infection

(2015) I-Yin Chen et al.   TRENDS IN MICROBIOLOGY

Reaching the melting point: Degradative enzymes and protease inhibitors involved in baculovirus infection and dissemination

(2015) Egide Ishimwe et al.   VIROLOGY

Inflammasome Activation in Response to the Yersinia Type III Secretion System Requires Hyperinjection of Translocon Proteins YopB and YopD

(2015) Erin E. Zwack et al.   mBio

Inhibition of inflammasome activation by Coxiella burnetii type IV secretion system effector IcaA

(2015) Larissa D. Cunha et al.   Nature Communications

Enteropathogenic Escherichia coli Uses NleA to Inhibit NLRP3 Inflammasome Activation

(2015) Hilo Yen et al.   PLoS Pathogens

Yersinia pestis Activates Both IL-1β and IL-1 Receptor Antagonist to Modulate Lung Inflammation during Pneumonic Plague

(2015) Vijay Sivaraman et al.   PLoS Pathogens

Assembly and structure of the T3SS

(2014) Brianne J. Burkinshaw et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Noncanonical Inflammasome Activation of Caspase-4/Caspase-11 Mediates Epithelial Defenses against Enteric Bacterial Pathogens

(2014) Leigh A. Knodler et al.   Cell Host & Microbe

Salmonellae PhoPQ regulation of the outer membrane to resist innate immunity

(2014) Zachary D Dalebroux et al.   CURRENT OPINION IN MICROBIOLOGY

Structural mechanisms of inflammasome assembly

(2014) Alvin Lu et al.   FEBS Journal

Master manipulators: an update on Legionella pneumophila Icm/Dot translocated substrates and their host targets

(2014) Dervla T Isaac et al.   Future Microbiology

Influenza virus non-structural protein NS1: interferon antagonism and beyond

(2014) D. Marc   JOURNAL OF GENERAL VIROLOGY

Cigarette Smoke-Induced Pulmonary Inflammation Is TLR4/MyD88 and IL-1R1/MyD88 Signaling Dependent

(2014) E. Doz et al.   JOURNAL OF IMMUNOLOGY

Helicobacter pylori–Induced IL-1β Secretion in Innate Immune Cells Is Regulated by the NLRP3 Inflammasome and Requires the Cag Pathogenicity Island

(2014) Raphaela P. Semper et al.   JOURNAL OF IMMUNOLOGY

Mutually repressing repressor functions and multi-layered cellular heterogeneity regulate the bistableSalmonella fliCcensus

(2014) Mary K. Stewart et al.   MOLECULAR MICROBIOLOGY

Caspase-11 activation requires lysis of pathogen-containing vacuoles by IFN-induced GTPases

(2014) Etienne Meunier et al.   NATURE

The adaptor ASC has extracellular and 'prionoid' activities that propagate inflammation

(2014) Bernardo S Franklin et al.   NATURE IMMUNOLOGY

Bacteria–autophagy interplay: a battle for survival

(2014) Ju Huang et al.   NATURE REVIEWS MICROBIOLOGY

Guanylate binding proteins promote caspase-11-dependent pyroptosis in response to cytoplasmic LPS

(2014) D. M. Pilla et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Caspase-1 autoproteolysis is differentially required for NLRP1b and NLRP3 inflammasome function

(2014) Baptiste Guey et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Spatial Segregation of Virulence Gene Expression during Acute Enteric Infection with Salmonella enterica serovar Typhimurium

(2014) R. C. Laughlin et al.   mBio

Activation of the NLRP1b inflammasome independently of ASC-mediated caspase-1 autoproteolysis and speck formation

(2014) Nina Van Opdenbosch et al.   Nature Communications

Inflammasome Sensor NLRP1 Controls Rat Macrophage Susceptibility to Toxoplasma gondii

(2014) Kimberly M. Cirelli et al.   PLoS Pathogens

The Shigella OspC3 Effector Inhibits Caspase-4, Antagonizes Inflammatory Cell Death, and Promotes Epithelial Infection

(2013) Taira Kobayashi et al.   Cell Host & Microbe

The Cag pathogenicity island and interaction between TLR2/NOD2 and NLRP3 regulate IL-1β production inHelicobacter pyloriinfected dendritic cells

(2013) Dong-Jae Kim et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Poxviruses and the evolution of host range and virulence

(2013) Sherry L. Haller et al.   INFECTION GENETICS AND EVOLUTION

Repression of Inflammasome by Francisella tularensis during Early Stages of Infection

(2013) Rachel J. Dotson et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cutting Edge: Mouse NAIP1 Detects the Type III Secretion System Needle Protein

(2013) M. Rayamajhi et al.   JOURNAL OF IMMUNOLOGY

Cell death by pyroptosis drives CD4 T-cell depletion in HIV-1 infection

(2013) Gilad Doitsh et al.   NATURE

Fortifying the barrier: the impact of lipid A remodelling on bacterial pathogenesis

(2013) Brittany D. Needham et al.   NATURE REVIEWS MICROBIOLOGY

Vaccinia virus F1L protein promotes virulence by inhibiting inflammasome activation

(2013) M. Gerlic et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cytoplasmic LPS Activates Caspase-11: Implications in TLR4-Independent Endotoxic Shock

(2013) J. A. Hagar et al.   SCIENCE

Caspase-11 Protects Against Bacteria That Escape the Vacuole

(2013) Y. Aachoui et al.   SCIENCE

Inflammasome Components Coordinate Autophagy and Pyroptosis as Macrophage Responses to Infection

(2013) B. G. Byrne et al.   mBio

Type I IFN Triggers RIG-I/TLR3/NLRP3-dependent Inflammasome Activation in Influenza A Virus Infected Cells

(2013) Julien Pothlichet et al.   PLoS Pathogens

Regulation of the Yersinia type III secretion system: traffic control

(2013) Rebecca S. Dewoody et al.   Frontiers in Cellular and Infection Microbiology

Neutrophil Function: From Mechanisms to Disease

(2012) Borko Amulic et al.   Annual Review of Immunology

Recognition of Bacteria by Inflammasomes

(2012) Jakob von Moltke et al.   Annual Review of Immunology

TRIF Licenses Caspase-11-Dependent NLRP3 Inflammasome Activation by Gram-Negative Bacteria

(2012) Vijay A.K. Rathinam et al.   CELL

The Yersinia Virulence Effector YopM Binds Caspase-1 to Arrest Inflammasome Assembly and Processing

(2012) Christopher N. LaRock et al.   Cell Host & Microbe

Innate immune recognition of flagellin limits systemic persistence ofBrucella

(2012) Matthieu Terwagne et al.   CELLULAR MICROBIOLOGY

The NLRP12 Inflammasome Recognizes Yersinia pestis

(2012) Gregory I. Vladimer et al.   IMMUNITY

Non-transcriptional Priming and Deubiquitination Regulate NLRP3 Inflammasome Activation

(2012) Christine Juliana et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Autolytic Proteolysis within the Function to Find Domain (FIIND) Is Required for NLRP1 Inflammasome Activity

(2012) Joshua N. Finger et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Toll or Interleukin-1 Receptor (TIR) Domain-containing Adaptor Inducing Interferon-β (TRIF)-mediated Caspase-11 Protease Production Integrates Toll-like Receptor 4 (TLR4) Protein- and Nlrp3 Inflammasome-mediated Host Defense against Enteropathogens

(2012) Prajwal Gurung et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cutting Edge: IL-1β Processing during Pseudomonas aeruginosa Infection Is Mediated by Neutrophil Serine Proteases and Is Independent of NLRC4 and Caspase-1

(2012) Mausita Karmakar et al.   JOURNAL OF IMMUNOLOGY

Caspase-11 increases susceptibility to Salmonella infection in the absence of caspase-1

(2012) Petr Broz et al.   NATURE

Phosphorylation of NLRC4 is critical for inflammasome activation

(2012) Yan Qu et al.   NATURE

Activation of autophagy by inflammatory signals limits IL-1β production by targeting ubiquitinated inflammasomes for destruction

(2012) Chong-Shan Shi et al.   NATURE IMMUNOLOGY

Treating inflammation by blocking interleukin-1 in a broad spectrum of diseases

(2012) Charles A. Dinarello et al.   NATURE REVIEWS DRUG DISCOVERY

Viroporins: structure and biological functions

(2012) José Luis Nieva et al.   NATURE REVIEWS MICROBIOLOGY

LPS remodeling is an evolved survival strategy for bacteria

(2012) Y. Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Non-genetic diversity shapes infectious capacity and host resistance

(2012) Mary K. Stewart et al.   TRENDS IN MICROBIOLOGY

A Unique Bivalent Binding and Inhibition Mechanism by the Yatapoxvirus Interleukin 18 Binding Protein

(2012) Brian Krumm et al.   PLoS Pathogens

Anthrax Lethal Factor Cleavage of Nlrp1 Is Required for Activation of the Inflammasome

(2012) Jonathan L. Levinsohn et al.   PLoS Pathogens

IFI16 Acts as a Nuclear Pathogen Sensor to Induce the Inflammasome in Response to Kaposi Sarcoma-Associated Herpesvirus Infection

(2011) Nagaraj Kerur et al.   Cell Host & Microbe

Type I Interferon Inhibits Interleukin-1 Production and Inflammasome Activation

(2011) Greta Guarda et al.   IMMUNITY

Uncoupling of Pyrin-only Protein 2 (POP2)-mediated Dual Regulation of NF-κB and the Inflammasome

(2011) Maninjay K. Atianand et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Coordinated Host Responses during Pyroptosis: Caspase-1-Dependent Lysosome Exocytosis and Inflammatory Cytokine Maturation

(2011) T. Bergsbaken et al.   JOURNAL OF IMMUNOLOGY

Measles Virus V Protein Inhibits NLRP3 Inflammasome-Mediated Interleukin-1  Secretion

(2011) N. Komune et al.   JOURNAL OF VIROLOGY

The Ectromelia Virus SPI-2 Protein Causes Lethal Mousepox by Preventing NK Cell Responses

(2011) C. R. Melo-Silva et al.   JOURNAL OF VIROLOGY

Myxoma Virus Lacking the Pyrin-Like Protein M013 Is Sensed in Human Myeloid Cells by both NLRP3 and Multiple Toll-Like Receptors, Which Independently Activate the Inflammasome and NF- B Innate Response Pathways

(2011) M. M. Rahman et al.   JOURNAL OF VIROLOGY

The NLRC4 inflammasome receptors for bacterial flagellin and type III secretion apparatus

(2011) Yue Zhao et al.   NATURE

Innate immune recognition of bacterial ligands by NAIPs determines inflammasome specificity

(2011) Eric M. Kofoed et al.   NATURE

Non-canonical inflammasome activation targets caspase-11

(2011) Nobuhiko Kayagaki et al.   NATURE

Regulation of phenotypic heterogeneity permits Salmonella evasion of the host caspase-1 inflammatory response

(2011) M. K. Stewart et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Intestinal inflammation allows Salmonella to use ethanolamine to compete with the microbiota

(2011) P. Thiennimitr et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Discovery of a Viral NLR Homolog that Inhibits the Inflammasome

(2011) S. M. Gregory et al.   SCIENCE

The Inflammasomes

(2010) Kate Schroder et al.   CELL

A Yersinia Effector Protein Promotes Virulence by Preventing Inflammasome Recognition of the Type III Secretion System

(2010) Igor E. Brodsky et al.   Cell Host & Microbe

Microreview: Innate immune encounters of the (Type) 4th kind: Brucella

(2010) Maarten F. De Jong et al.   CELLULAR MICROBIOLOGY

Recognition of viruses by cytoplasmic sensors

(2010) Courtney Wilkins et al.   CURRENT OPINION IN IMMUNOLOGY

Taming the Elephant: Salmonella Biology, Pathogenesis, and Prevention

(2010) H. L. Andrews-Polymenis et al.   INFECTION AND IMMUNITY

Redundant roles for inflammasome receptors NLRP3 and NLRC4 in host defense againstSalmonella

(2010) Petr Broz et al.   JOURNAL OF EXPERIMENTAL MEDICINE

A role for mitochondria in NLRP3 inflammasome activation

(2010) Rongbin Zhou et al.   NATURE

Gut inflammation provides a respiratory electron acceptor for Salmonella

(2010) Sebastian E. Winter et al.   NATURE

The AIM2 inflammasome is essential for host defense against cytosolic bacteria and DNA viruses

(2010) Vijay A K Rathinam et al.   NATURE IMMUNOLOGY

The AIM2 inflammasome is critical for innate immunity to Francisella tularensis

(2010) Teresa Fernandes-Alnemri et al.   NATURE IMMUNOLOGY

Caspase-1-induced pyroptosis is an innate immune effector mechanism against intracellular bacteria

(2010) Edward A Miao et al.   NATURE IMMUNOLOGY

Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasome

(2010) Kiichi Nakahira et al.   NATURE IMMUNOLOGY

Dissemination of invasiveSalmonellavia bacterial-induced extrusion of mucosal epithelia

(2010) Leigh A. Knodler et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Innate immune detection of the type III secretion apparatus through the NLRC4 inflammasome

(2010) E. A. Miao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Immunological and Inflammatory Functions of the Interleukin-1 Family

(2009) Charles A. Dinarello   Annual Review of Immunology

Control of Salmonella pathogenicity island-2 gene expression

(2009) Ephraim Fass et al.   CURRENT OPINION IN MICROBIOLOGY

Cutting Edge: NF- B Activating Pattern Recognition and Cytokine Receptors License NLRP3 Inflammasome Activation by Regulating NLRP3 Expression

(2009) F. G. Bauernfeind et al.   JOURNAL OF IMMUNOLOGY

Innate immune response during Yersinia infection: critical modulation of cell death mechanisms through phagocyte activation

(2009) Tessa Bergsbaken et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Biological Diversity of Prokaryotic Type IV Secretion Systems

(2009) C. E. Alvarez-Martinez et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

The Francisella tularensis pathogenicity island encodes a secretion system that is required for phagosome escape and virulence

(2009) Jeffrey R. Barker et al.   MOLECULAR MICROBIOLOGY

Pyroptosis: host cell death and inflammation

(2009) Tessa Bergsbaken et al.   NATURE REVIEWS MICROBIOLOGY

Motility allows S. Typhimurium to benefit from the mucosal defence

(2008) Bärbel Stecher et al.   CELLULAR MICROBIOLOGY

The NLR Gene Family: A Standard Nomenclature

(2008) Jenny P.-Y. Ting et al.   IMMUNITY

Flightless-I regulates proinflammatory caspases by selectively modulating intracellular localization and caspase activity

(2008) Juying Li et al.   JOURNAL OF CELL BIOLOGY

Anthrax lethal toxin and Salmonella elicit the common cell death pathway of caspase-1-dependent pyroptosis via distinct mechanisms

(2008) S. L. Fink et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The versatility of Shigella effectors

(2007) Michinaga Ogawa et al.   NATURE REVIEWS MICROBIOLOGY