Caspase-1 autoproteolysis is differentially required for NLRP1b and NLRP3 inflammasome function

Prion-like Polymerization Underlies Signal Transduction in Antiviral Immune Defense and Inflammasome Activation

(2014) Xin Cai et al.   CELL

Activation of the NLRP1b inflammasome independently of ASC-mediated caspase-1 autoproteolysis and speck formation

(2014) Nina Van Opdenbosch et al.   Nature Communications

Structure of the NLRP1 caspase recruitment domain suggests potential mechanisms for its association with procaspase-1

(2013) Tengchuan Jin et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

NLRP1-Dependent Pyroptosis Leads to Acute Lung Injury and Morbidity in Mice

(2012) M. Kovarova et al.   JOURNAL OF IMMUNOLOGY

Inflammasomes in health and disease

(2012) Till Strowig et al.   NATURE

Differential Expression of NLRP3 among Hematopoietic Cells

(2011) G. Guarda et al.   JOURNAL OF IMMUNOLOGY

The Inflammasomes

(2010) Kate Schroder et al.   CELL

Differential Requirement for Caspase-1 Autoproteolysis in Pathogen-Induced Cell Death and Cytokine Processing

(2010) Petr Broz et al.   Cell Host & Microbe

Crystal Structure of Procaspase-1 Zymogen Domain Reveals Insight into Inflammatory Caspase Autoactivation

(2009) J. Michael Elliott et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cutting Edge: NF- B Activating Pattern Recognition and Cytokine Receptors License NLRP3 Inflammasome Activation by Regulating NLRP3 Expression

(2009) F. G. Bauernfeind et al.   JOURNAL OF IMMUNOLOGY

AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC

(2009) Veit Hornung et al.   NATURE

The inflammasome recognizes cytosolic microbial and host DNA and triggers an innate immune response

(2008) Daniel A. Muruve et al.   NATURE