A network-biology perspective of microRNA function and dysfunction in cancer

miR-892b Silencing Activates NF- B and Promotes Aggressiveness in Breast Cancer

(2016) L. Jiang et al.   CANCER RESEARCH

Aberrant PD-L1 expression through 3′-UTR disruption in multiple cancers

(2016) Keisuke Kataoka et al.   NATURE

Multiple mechanisms disrupt the let-7 microRNA family in neuroblastoma

(2016) John T. Powers et al.   NATURE

Endogenous microRNA sponges: evidence and controversy

(2016) Daniel W. Thomson et al.   NATURE REVIEWS GENETICS

miRNet - dissecting miRNA-target interactions and functional associations through network-based visual analysis

(2016) Yannan Fan et al.   NUCLEIC ACIDS RESEARCH

Understanding microRNA-mediated gene regulatory networks through mathematical modelling

(2016) Xin Lai et al.   NUCLEIC ACIDS RESEARCH

miEAA: microRNA enrichment analysis and annotation

(2016) Christina Backes et al.   NUCLEIC ACIDS RESEARCH

Integrative analyses reveal a long noncoding RNA-mediated sponge regulatory network in prostate cancer

(2016) Zhou Du et al.   Nature Communications

Elucidating MicroRNA Regulatory Networks Using Transcriptional, Post-transcriptional, and Histone Modification Measurements

(2016) Sara J.C. Gosline et al.   Cell Reports

Bias in microRNA functional enrichment analysis

(2015) Thomas Bleazard et al.   BIOINFORMATICS

miSEA: microRNA set enrichment analysis

(2015) M.Erdem Çorapçıoğlu et al.   BIOSYSTEMS

miR-634 Activates the Mitochondrial Apoptosis Pathway and Enhances Chemotherapy-Induced Cytotoxicity

(2015) Naoto Fujiwara et al.   CANCER RESEARCH

MicroRNA polymorphisms as markers of risk, prognosis and treatment response in hematological malignancies

(2015) Agnieszka Dzikiewicz-Krawczyk   CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY

MicroRNAs in cancer therapeutics: “from the bench to the bedside”

(2015) Paloma del C Monroig-Bosque et al.   EXPERT OPINION ON BIOLOGICAL THERAPY

Genome-wide profiling of polyadenylation sites reveals a link between selective polyadenylation and cancer metastasis

(2015) D.-P. Lai et al.   HUMAN MOLECULAR GENETICS

MicroRNA-542-3p Suppresses Tumor Cell Invasion via Targeting AKT Pathway in Human Astrocytoma

(2015) Junchao Cai et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Autocrine/Paracrine Human Growth Hormone-stimulated MicroRNA 96-182-183 Cluster Promotes Epithelial-Mesenchymal Transition and Invasion in Breast Cancer

(2015) Weijie Zhang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

An allelic series of miR-17∼92–mutant mice uncovers functional specialization and cooperation among members of a microRNA polycistron

(2015) Yoon-Chi Han et al.   NATURE GENETICS

Towards a molecular understanding of microRNA-mediated gene silencing

(2015) Stefanie Jonas et al.   NATURE REVIEWS GENETICS

Regulation of mammalian transcription and splicing by Nuclear RNAi

(2015) Roya Kalantari et al.   NUCLEIC ACIDS RESEARCH

Beyond the one-locus-one-miRNA paradigm: microRNA isoforms enable deeper insights into breast cancer heterogeneity

(2015) Aristeidis G. Telonis et al.   NUCLEIC ACIDS RESEARCH

KEGG as a reference resource for gene and protein annotation

(2015) Minoru Kanehisa et al.   NUCLEIC ACIDS RESEARCH

Large-scale profiling of microRNAs for The Cancer Genome Atlas

(2015) Andy Chu et al.   NUCLEIC ACIDS RESEARCH

Pathway analysis from lists of microRNAs: common pitfalls and alternative strategy

(2015) Patrice Godard et al.   NUCLEIC ACIDS RESEARCH

miR-200 promotes the mesenchymal to epithelial transition by suppressing multiple members of the Zeb2 and Snail1 transcriptional repressor complexes

(2015) R Perdigão-Henriques et al.   ONCOGENE

Genome-wide screen identified let-7c/miR-99a/miR-125b regulating tumor progression and stem-like properties in cholangiocarcinoma

(2015) K-Y Lin et al.   ONCOGENE

Pleuropulmonary Blastoma: Evolution of an Entity as an Entry into a Familial Tumor Predisposition Syndrome

(2015) Louis P. Dehner et al.   PEDIATRIC AND DEVELOPMENTAL PATHOLOGY

Divergent target recognition by coexpressed 5′-isomiRs of miR-142-3p and selective viral mimicry

(2015) Mark Manzano et al.   RNA

Dysregulation of microRNA biogenesis and gene silencing in cancer

(2015) Akiko Hata et al.   Science Signaling

Fibroblast Growth Factor 9 Regulation by MicroRNAs Controls Lung Development and Links DICER1 Loss to the Pathogenesis of Pleuropulmonary Blastoma

(2015) Yongjun Yin et al.   PLoS Genetics

Predicting effective microRNA target sites in mammalian mRNAs

(2015) Vikram Agarwal et al.   eLife

Dysregulation of microRNA biogenesis and gene silencing in cancer

(2015) Akiko Hata et al.   Science Signaling

Mirin: identifying microRNA regulatory modules in protein–protein interaction networks

(2014) Ken-Chi Yang et al.   BIOINFORMATICS

Composition of seed sequence is a major determinant of microRNA targeting patterns

(2014) X. Wang   BIOINFORMATICS

Computational analysis identifies a sponge interaction network between long non-coding RNAs and messenger RNAs in human breast cancer

(2014) Paola Paci et al.   BMC Systems Biology

Hippo Signaling Regulates Microprocessor and Links Cell-Density-Dependent miRNA Biogenesis to Cancer

(2014) Masaki Mori et al.   CELL

Aberrant Regulation and Function of MicroRNAs in Cancer

(2014) Brian D. Adams et al.   CURRENT BIOLOGY

Genome-wide identification of miR-200 targets reveals a regulatory network controlling cell invasion

(2014) C. P. Bracken et al.   EMBO JOURNAL

Direct transcriptional regulation by nuclear microRNAs

(2014) Marika Salmanidis et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

MicroRNAs 206 and 21 Cooperate To Promote RAS-Extracellular Signal-Regulated Kinase Signaling by Suppressing the Translation of RASA1 and SPRED1

(2014) S. B. Sharma et al.   MOLECULAR AND CELLULAR BIOLOGY

Assessing the ceRNA Hypothesis with Quantitative Measurements of miRNA and Target Abundance

(2014) Rémy Denzler et al.   MOLECULAR CELL

Endogenous miRNA and Target Concentrations Determine Susceptibility to Potential ceRNA Competition

(2014) Andrew D. Bosson et al.   MOLECULAR CELL

mRNA Destabilization Is the Dominant Effect of Mammalian MicroRNAs by the Time Substantial Repression Ensues

(2014) Stephen W. Eichhorn et al.   MOLECULAR CELL

Identification and consequences of miRNA–target interactions — beyond repression of gene expression

(2014) Jean Hausser et al.   NATURE REVIEWS GENETICS

A novel AP-1/miR-101 regulatory feedback loop and its implication in the migration and invasion of hepatoma cells

(2014) Jing-Jing Liu et al.   NUCLEIC ACIDS RESEARCH

Cooperative gene regulation by microRNA pairs and their identification using a computational workflow

(2014) Ulf Schmitz et al.   NUCLEIC ACIDS RESEARCH

miRDB: an online resource for microRNA target prediction and functional annotations

(2014) Nathan Wong et al.   NUCLEIC ACIDS RESEARCH

A combinatorial microRNA therapeutics approach to suppressing non-small cell lung cancer

(2014) A L Kasinski et al.   ONCOGENE

MicroRNA-193a-3p and -5p suppress the metastasis of human non-small-cell lung cancer by downregulating the ERBB4/PIK3R3/mTOR/S6K2 signaling pathway

(2014) T Yu et al.   ONCOGENE

MicroRNA-133a Suppresses Multiple Oncogenic Membrane Receptors and Cell Invasion in Non-Small Cell Lung Carcinoma

(2014) Lu-Kai Wang et al.   PLoS One

Structural basis for microRNA targeting

(2014) N. T. Schirle et al.   SCIENCE

MicroRNAs in cancer: biomarkers, functions and therapy

(2014) Josie Hayes et al.   TRENDS IN MOLECULAR MEDICINE

Somatic mutations in DROSHA and DICER1 impair microRNA biogenesis through distinct mechanisms in Wilms tumours

(2014) Dinesh Rakheja et al.   Nature Communications

Recurrent somatic mutation in DROSHA induces microRNA profile changes in Wilms tumour

(2014) Giovana T. Torrezan et al.   Nature Communications

Sequencing of Captive Target Transcripts Identifies the Network of Regulated Genes and Functions of Primate-Specific miR-522

(2014) Shen Mynn Tan et al.   Cell Reports

MicroRNAs as therapeutic targets in human cancers

(2014) Maitri Y. Shah et al.   Wiley Interdisciplinary Reviews-RNA

Integrated Analyses Identify a Master MicroRNA Regulatory Network for the Mesenchymal Subtype in Serous Ovarian Cancer

(2013) Da Yang et al.   CANCER CELL

miR-192, miR-194 and miR-215: a convergent microRNA network suppressing tumor progression in renal cell carcinoma

(2013) H.W.Z. Khella et al.   CARCINOGENESIS

Mapping the Human miRNA Interactome by CLASH Reveals Frequent Noncanonical Binding

(2013) Aleksandra Helwak et al.   CELL

Endogenous miRNA Sponge lincRNA-RoR Regulates Oct4, Nanog, and Sox2 in Human Embryonic Stem Cell Self-Renewal

(2013) Yue Wang et al.   DEVELOPMENTAL CELL

MicroRNAs Cooperatively Inhibit a Network of Tumor Suppressor Genes to Promote Pancreatic Tumor Growth and Progression

(2013) Adam E. Frampton et al.   GASTROENTEROLOGY

MicroRNA-related sequence variations in human cancers

(2013) A. Wojcicka et al.   HUMAN GENETICS

Mature miR-17-5p and passenger miR-17-3p induce hepatocellular carcinoma by targeting PTEN, GalNT7 and vimentin in different signal pathways

(2013) S. W. Shan et al.   JOURNAL OF CELL SCIENCE

The Role of miRNAs in Regulating Gene Expression Networks

(2013) Allan M. Gurtan et al.   JOURNAL OF MOLECULAR BIOLOGY

Natural RNA circles function as efficient microRNA sponges

(2013) Thomas B. Hansen et al.   NATURE

Circular RNAs are a large class of animal RNAs with regulatory potency

(2013) Sebastian Memczak et al.   NATURE

Mutations in regulators of the epigenome and their connections to global chromatin patterns in cancer

(2013) Christoph Plass et al.   NATURE REVIEWS GENETICS

Treatment of HCV Infection by Targeting MicroRNA

(2013) Harry L.A. Janssen et al.   NEW ENGLAND JOURNAL OF MEDICINE

miR-23b regulates cytoskeletal remodeling, motility and metastasis by directly targeting multiple transcripts

(2013) Loredana Pellegrino et al.   NUCLEIC ACIDS RESEARCH

Comprehensive analysis of the functional microRNA–mRNA regulatory network identifies miRNA signatures associated with glioma malignant progression

(2013) Yongsheng Li et al.   NUCLEIC ACIDS RESEARCH

MiR-200 can repress breast cancer metastasis through ZEB1-independent but moesin-dependent pathways

(2013) X Li et al.   ONCOGENE

DICER1mutations in an adolescent with cervical embryonal rhabdomyosarcoma (cERMS)

(2013) Eva Tomiak et al.   PEDIATRIC BLOOD & CANCER

Beta Cell 5′-Shifted isomiRs Are Candidate Regulatory Hubs in Type 2 Diabetes

(2013) Jeanette Baran-Gale et al.   PLoS One

Insulin growth factor signaling is regulated by microRNA-486, an underexpressed microRNA in lung cancer

(2013) Y. Peng et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

miR-139-5p is a regulator of metastatic pathways in breast cancer

(2013) K. Krishnan et al.   RNA

Modulation of epigenetic regulators and cell fate decisions by miRNAs

(2013) Andreas J Gruber et al.   Epigenomics

MicroRNA-135b promotes lung cancer metastasis by regulating multiple targets in the Hippo pathway and LZTS1

(2013) Ching-Wen Lin et al.   Nature Communications

MicroRNA-independent roles of the RNase III enzymes Drosha and Dicer

(2013) T. M. Johanson et al.   Open Biology

Functional Genomic Analysis of the let-7 Regulatory Network in Caenorhabditis elegans

(2013) Shaun E. Hunter et al.   PLoS Genetics

miRTrail - a comprehensive webserver for analyzing gene and miRNA patterns to enhance the understanding of regulatory mechanisms in diseases

(2012) Cedric Laczny et al.   BMC BIOINFORMATICS

miR-192, miR-194, miR-215, miR-200c and miR-141 are downregulated and their common target ACVR2B is strongly expressed in renal childhood neoplasms

(2012) U. Senanayake et al.   CARCINOGENESIS

Roles for MicroRNAs in Conferring Robustness to Biological Processes

(2012) Margaret S. Ebert et al.   CELL

The Structure of Human Argonaute-2 in Complex with miR-20a

(2012) Elad Elkayam et al.   CELL

miR-34 and SNAIL form a double-negative feedback loop to regulate epithelial-mesenchymal transitions

(2012) Helge Siemens et al.   CELL CYCLE

KRAS alleles: The LCS6 3′UTR variant and KRAS coding sequence mutations in the NCI-60 panel

(2012) Samrat T. Kundu et al.   CELL CYCLE

microRNA-independent recruitment of Argonaute 1 to nanos mRNA through the Smaug RNA-binding protein

(2012) Benjamin D Pinder et al.   EMBO REPORTS

Identification of microRNA-regulated gene networks by expression analysis of target genes

(2012) Vincenzo Alessandro Gennarino et al.   GENOME RESEARCH

MiR-17-5p targets TP53INP1 and regulates cell proliferation and apoptosis of cervical cancer cells

(2012) Qian Wei et al.   IUBMB LIFE

MicroRNAs in the ImprintedDLK1-DIO3Region Repress the Epithelial-to-Mesenchymal Transition by Targeting the TWIST1 Protein Signaling Network

(2012) Christopher L. Haga et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Differentiation-associated microRNAs antagonize the Rb–E2F pathway to restrict proliferation

(2012) Matteo J. Marzi et al.   JOURNAL OF CELL BIOLOGY

MiR-182 overexpression in tumourigenesis of high-grade serous ovarian carcinoma

(2012) Zhaojian Liu et al.   JOURNAL OF PATHOLOGY

Global microRNA level regulation of EGFR-driven cell-cycle protein network in breast cancer

(2012) Stefan Uhlmann et al.   Molecular Systems Biology

Architecture of the human regulatory network derived from ENCODE data

(2012) Mark B. Gerstein et al.   NATURE

Drosha regulates neurogenesis by controlling Neurogenin 2 expression independent of microRNAs

(2012) Philip Knuckles et al.   NATURE NEUROSCIENCE

An alternative mode of microRNA target recognition

(2012) Sung Wook Chi et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

DIANA miRPath v.2.0: investigating the combinatorial effect of microRNAs in pathways

(2012) Ioannis S. Vlachos et al.   NUCLEIC ACIDS RESEARCH

miRNA target enrichment analysis reveals directly active miRNAs in health and disease

(2012) Israel Steinfeld et al.   NUCLEIC ACIDS RESEARCH

DIANA-LncBase: experimentally verified and computationally predicted microRNA targets on long non-coding RNAs

(2012) Maria D. Paraskevopoulou et al.   NUCLEIC ACIDS RESEARCH

A Novel YY1-miR-1 Regulatory Circuit in Skeletal Myogenesis Revealed by Genome-Wide Prediction of YY1-miRNA Network

(2012) Leina Lu et al.   PLoS One

miRSystem: An Integrated System for Characterizing Enriched Functions and Pathways of MicroRNA Targets

(2012) Tzu-Pin Lu et al.   PLoS One

MicroRNA-182-5p targets a network of genes involved in DNA repair

(2012) K. Krishnan et al.   RNA

IsomiRs – the overlooked repertoire in the dynamic microRNAome

(2012) Corine T. Neilsen et al.   TRENDS IN GENETICS

Elevated oncofoetal miR-17-5p expression regulates colorectal cancer progression by repressing its target gene P130

(2012) Yanlei Ma et al.   Nature Communications

MicroRNAs coordinately regulate protein complexes

(2011) Steffen Sass et al.   BMC Systems Biology

Gene set enrichment analysis: performance evaluation and usage guidelines

(2011) J.-H. Hung et al.   BRIEFINGS IN BIOINFORMATICS

MicroRNAs and epigenetics

(2011) Fumiaki Sato et al.   FEBS Journal

Drosha regulates hMSCs cell cycle progression through a miRNA independent mechanism

(2011) Adam Z. Oskowitz et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Two-tiered Approach Identifies a Network of Cancer and Liver Disease-related Genes Regulated by miR-122

(2011) Daniel R. Boutz et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A p53/miRNA-34 axis regulates Snail1-dependent cancer cell epithelial–mesenchymal transition

(2011) Nam Hee Kim et al.   JOURNAL OF CELL BIOLOGY

Characterizing the role of miRNAs within gene regulatory networks using integrative genomics techniques

(2011) W.-L. Su et al.   Molecular Systems Biology

DICER1 deficit induces Alu RNA toxicity in age-related macular degeneration

(2011) Hiroki Kaneko et al.   NATURE

Direct targeting of Sec23a by miR-200s influences cancer cell secretome and promotes metastatic colonization

(2011) Manav Korpal et al.   NATURE MEDICINE

Weak seed-pairing stability and high target-site abundance decrease the proficiency of lsy-6 and other microRNAs

(2011) David M Garcia et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Experimental strategies for microRNA target identification

(2011) D. W. Thomson et al.   NUCLEIC ACIDS RESEARCH

DICER1 Mutations in embryonal rhabdomyosarcomas from children with and without familial PPB-tumor predisposition syndrome

(2011) Leslie Doros et al.   PEDIATRIC BLOOD & CANCER

NAViGaTing the Micronome – Using Multiple MicroRNA Prediction Databases to Identify Signalling Pathway-Associated MicroRNAs

(2011) Elize A. Shirdel et al.   PLoS One

Functional SNP in the microRNA-367 binding site in the 3'UTR of the calcium channel ryanodine receptor gene 3 (RYR3) affects breast cancer risk and calcification

(2011) L. Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Densely Interconnected Genome-Wide Network of MicroRNAs and Oncogenic Pathways Revealed Using Gene Expression Signatures

(2011) Chia Huey Ooi et al.   PLoS Genetics

MicroRNAs and their isomiRs function cooperatively to target common biological pathways

(2011) Nicole Cloonan et al.   GENOME BIOLOGY

Hsa-mir-182 suppresses lung tumorigenesis through down regulation of RGS17 expression in vitro

(2010) Yihua Sun et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

CircuitsDB: a database of mixed microRNA/transcription factor feed-forward regulatory circuits in human and mouse

(2010) Olivier Friard et al.   BMC BIOINFORMATICS

Transcriptome-wide Identification of RNA-Binding Protein and MicroRNA Target Sites by PAR-CLIP

(2010) Markus Hafner et al.   CELL

Involvement of NF-κB/miR-448 regulatory feedback loop in chemotherapy-induced epithelial–mesenchymal transition of breast cancer cells

(2010) Q-Q Li et al.   CELL DEATH AND DIFFERENTIATION

Emerging Roles for Natural MicroRNA Sponges

(2010) Margaret S. Ebert et al.   CURRENT BIOLOGY

Mammalian microRNAs: experimental evaluation of novel and previously annotated genes

(2010) H. R. Chiang et al.   GENES & DEVELOPMENT

Canonical and alternate functions of the microRNA biogenesis machinery

(2010) M. M. W. Chong et al.   GENES & DEVELOPMENT

The miR-17-92 MicroRNA Cluster Regulates Multiple Components of the TGF-β Pathway in Neuroblastoma

(2010) Pieter Mestdagh et al.   MOLECULAR CELL

Genome-wide Dissection of MicroRNA Functions and Cotargeting Networks Using Gene Set Signatures

(2010) John S. Tsang et al.   MOLECULAR CELL

Smad Proteins Bind a Conserved RNA Sequence to Promote MicroRNA Maturation by Drosha

(2010) Brandi N. Davis et al.   MOLECULAR CELL

Expanding the MicroRNA Targeting Code: Functional Sites with Centered Pairing

(2010) Chanseok Shin et al.   MOLECULAR CELL

Target mRNA abundance dilutes microRNA and siRNA activity

(2010) Aaron Arvey et al.   Molecular Systems Biology

Mammalian microRNAs predominantly act to decrease target mRNA levels

(2010) Huili Guo et al.   NATURE

A coding-independent function of gene and pseudogene mRNAs regulates tumour biology

(2010) Laura Poliseno et al.   NATURE

Network medicine: a network-based approach to human disease

(2010) Albert-László Barabási et al.   NATURE REVIEWS GENETICS

Towards computational prediction of microRNA function and activity

(2010) Igor Ulitsky et al.   NUCLEIC ACIDS RESEARCH

starBase: a database for exploring microRNA–mRNA interaction maps from Argonaute CLIP-Seq and Degradome-Seq data

(2010) Jian-Hua Yang et al.   NUCLEIC ACIDS RESEARCH

MAGIA, a web-based tool for miRNA and Genes Integrated Analysis

(2010) G. Sales et al.   NUCLEIC ACIDS RESEARCH

Making RISC

(2010) Tomoko Kawamata et al.   TRENDS IN BIOCHEMICAL SCIENCES

HITS-CLIP: panoramic views of protein-RNA regulation in living cells

(2010) Robert B. Darnell   Wiley Interdisciplinary Reviews-RNA

Comprehensive modeling of microRNA targets predicts functional non-conserved and non-canonical sites

(2010) Doron Betel et al.   GENOME BIOLOGY

TargetMiner: microRNA target prediction with systematic identification of tissue-specific negative examples

(2009) Sanghamitra Bandyopadhyay et al.   BIOINFORMATICS

CORNA: testing gene lists for regulation by microRNAs

(2009) X. Wu et al.   BIOINFORMATICS

Clustered microRNAs' coordination in regulating protein-protein interaction network

(2009) Xiongying Yuan et al.   BMC Systems Biology

Posttranscriptional Crossregulation between Drosha and DGCR8

(2009) Jinju Han et al.   CELL

Architecture-Dependent Noise Discriminates Functionally Analogous Differentiation Circuits

(2009) Tolga Çağatay et al.   CELL

MicroRNAs: Target Recognition and Regulatory Functions

(2009) David P. Bartel   CELL

Widespread Shortening of 3′UTRs by Alternative Cleavage and Polyadenylation Activates Oncogenes in Cancer Cells

(2009) Christine Mayr et al.   CELL

Contextual extracellular cues promote tumor cell EMT and metastasis by regulating miR-200 family expression

(2009) D. L. Gibbons et al.   GENES & DEVELOPMENT

Genome-wide survey of microRNA–transcription factor feed-forward regulatory circuits in human

(2009) Angela Re et al.   Molecular BioSystems

Predicting microRNA targets and functions: traps for the unwary

(2009) William Ritchie et al.   NATURE METHODS

Causes and consequences of microRNA dysregulation in cancer

(2009) Carlo M. Croce   NATURE REVIEWS GENETICS

DIANA-microT web server: elucidating microRNA functions through target prediction

(2009) M. Maragkakis et al.   NUCLEIC ACIDS RESEARCH

MicroRNA and mRNA integrated analysis (MMIA): a web tool for examining biological functions of microRNA expression

(2009) Seungyoon Nam et al.   NUCLEIC ACIDS RESEARCH

Protein lysate microarray analysis to identify microRNAs regulating estrogen receptor signaling in breast cancer cell lines

(2009) S-K Leivonen et al.   ONCOGENE

Progressive lengthening of 3' untranslated regions of mRNAs by alternative polyadenylation during mouse embryonic development

(2009) Z. Ji et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

DICER1 Mutations in Familial Pleuropulmonary Blastoma

(2009) D. A. Hill et al.   SCIENCE

Therapeutic Silencing of MicroRNA-122 in Primates with Chronic Hepatitis C Virus Infection

(2009) R. E. Lanford et al.   SCIENCE

Concordant Regulation of Translation and mRNA Abundance for Hundreds of Targets of a Human microRNA

(2009) David G. Hendrickson et al.   PLOS BIOLOGY

A SNP in a let-7 microRNA Complementary Site in the KRAS 3' Untranslated Region Increases Non-Small Cell Lung Cancer Risk

(2008) L. J. Chin et al.   CANCER RESEARCH

A Double-Negative Feedback Loop between ZEB1-SIP1 and the microRNA-200 Family Regulates Epithelial-Mesenchymal Transition

(2008) C. P. Bracken et al.   CANCER RESEARCH

A reciprocal repression between ZEB1 and members of the miR-200 family promotes EMT and invasion in cancer cells

(2008) Ulrike Burk et al.   EMBO REPORTS

A C. elegans genome-scale microRNA network contains composite feedback motifs with high flux capacity

(2008) N. J. Martinez et al.   GENES & DEVELOPMENT

The miR-200 family determines the epithelial phenotype of cancer cells by targeting the E-cadherin repressors ZEB1 and ZEB2

(2008) S.-M. Park et al.   GENES & DEVELOPMENT

Most mammalian mRNAs are conserved targets of microRNAs

(2008) R. C. Friedman et al.   GENOME RESEARCH

The miR-200 Family Inhibits Epithelial-Mesenchymal Transition and Cancer Cell Migration by Direct Targeting of E-cadherin Transcriptional RepressorsZEB1andZEB2

(2008) Manav Korpal et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The impact of microRNAs on protein output

(2008) Daehyun Baek et al.   NATURE

Widespread changes in protein synthesis induced by microRNAs

(2008) Matthias Selbach et al.   NATURE

Structure of an argonaute silencing complex with a seed-containing guide DNA and target RNA duplex

(2008) Yanli Wang et al.   NATURE

The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1

(2008) Philip A. Gregory et al.   NATURE CELL BIOLOGY

Stochastic switching as a survival strategy in fluctuating environments

(2008) Murat Acar et al.   NATURE GENETICS

Genome-Wide Analysis of MEF2 Transcriptional Program Reveals Synaptic Target Genes and Neuronal Activity-Dependent Polyadenylation Site Selection

(2008) Steven W. Flavell et al.   NEURON

Dicer, Drosha, and Outcomes in Patients with Ovarian Cancer

(2008) William M. Merritt et al.   NEW ENGLAND JOURNAL OF MEDICINE

A regulatory interplay between miR-27a and Runx1 during megakaryopoiesis

(2008) O. Ben-Ami et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MicroRNA regulation of a cancer network: Consequences of the feedback loops involving miR-17-92, E2F, and Myc

(2008) B. D. Aguda et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A microRNA DNA methylation signature for human cancer metastasis

(2008) A. Lujambio et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Characterization of microRNA-regulated protein-protein interaction network

(2008) Chun-Wei Hsu et al.   PROTEOMICS

Proliferating Cells Express mRNAs with Shortened 3' Untranslated Regions and Fewer MicroRNA Target Sites

(2008) R. Sandberg et al.   SCIENCE