Clinical Grade Manufacturing of Human Alloantigen-Reactive Regulatory T Cells for Use in Transplantation

CD28 Costimulation Is Essential for Human T Regulatory Expansion and Function

(2014) T. N. Golovina et al.   JOURNAL OF IMMUNOLOGY

Obtaining regulatory T cells from uraemic patients awaiting kidney transplantation for use in clinical trials

(2013) D. Berglund et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

IL-5 promotes induction of antigen-specific CD4+CD25+ T regulatory cells that suppress autoimmunity

(2012) G. T. Tran et al.   BLOOD

Regulatory T-cell therapy for transplantation

(2012) Qizhi Tang et al.   Current Opinion in Organ Transplantation

Administration of CD4+CD25highCD127- Regulatory T Cells Preserves  -Cell Function in Type 1 Diabetes in Children

(2012) N. Marek-Trzonkowska et al.   DIABETES CARE

Xenogeneic Graft-versus-Host-Disease in NOD-scid IL-2Rγnull Mice Display a T-Effector Memory Phenotype

(2012) Niwa Ali et al.   PLoS One

Ex vivo expansion of human Tregs specific for alloantigens presented directly or indirectly

(2011) A. Veerapathran et al.   BLOOD

Tregs prevent GVHD and promote immune reconstitution in HLA-haploidentical transplantation

(2011) M. Di Ianni et al.   BLOOD

Plasticity of Human Regulatory T Cells in Healthy Subjects and Patients with Type 1 Diabetes

(2011) Stephanie A. McClymont et al.   JOURNAL OF IMMUNOLOGY

Engineered artificial antigen presenting cells facilitate direct and efficient expansion of tumor infiltrating lymphocytes

(2011) Qunrui Ye et al.   Journal of Translational Medicine

Establishment of Antitumor Memory in Humans Using in Vitro-Educated CD8+ T Cells

(2011) M. O. Butler et al.   Science Translational Medicine

Human Regulatory T Cells with Alloantigen Specificity Are More Potent Inhibitors of Alloimmune Skin Graft Damage than Polyclonal Regulatory T Cells

(2011) P. Sagoo et al.   Science Translational Medicine

Isolation, expansion and functional assessment of CD4+CD25+FoxP3+ regulatory T cells and Tr1 cells from uremic patients awaiting kidney transplantation

(2011) David Berglund et al.   TRANSPLANT IMMUNOLOGY

CD4+Foxp3+ regulatory T cell therapy in transplantation

(2011) Q. Tang et al.   Journal of Molecular Cell Biology

Infusion of ex vivo expanded T regulatory cells in adults transplanted with umbilical cord blood: safety profile and detection kinetics

(2010) C. G. Brunstein et al.   BLOOD

K562/GM-CSF Immunotherapy Reduces Tumor Burden in Chronic Myeloid Leukemia Patients with Residual Disease on Imatinib Mesylate

(2010) B. D. Smith et al.   CLINICAL CANCER RESEARCH

Granulocyte-macrophage colony-stimulating factor (GM-CSF)-secreting cellular immunotherapy in combination with autologous stem cell transplantation (ASCT) as postremission therapy for acute myeloid leukemia (AML)

(2009) I. M. Borrello et al.   BLOOD

Quantitative DNA Methylation Analysis of FOXP3 as a New Method for Counting Regulatory T Cells in Peripheral Blood and Solid Tissue

(2009) G. Wieczorek et al.   CANCER RESEARCH

First-in-man clinical results of the treatment of patients with graft versus host disease with human ex vivo expanded CD4+CD25+CD127− T regulatory cells

(2009) Piotr Trzonkowski et al.   CLINICAL IMMUNOLOGY

Direct Expansion of Human Allospecific FoxP3+CD4+ Regulatory T Cells with Allogeneic B Cells for Therapeutic Application

(2009) L. C. Chen et al.   JOURNAL OF IMMUNOLOGY

Expansion of Human Regulatory T-Cells From Patients With Type 1 Diabetes

(2008) A. L. Putnam et al.   DIABETES

Reprogramming the immune system: co-receptor blockade as a paradigm for harnessing tolerance mechanisms

(2008) Herman Waldmann et al.   IMMUNOLOGICAL REVIEWS

Conferring indirect allospecificity on CD4+CD25+ Tregs by TCR gene transfer favors transplantation tolerance in mice

(2008) Julia Yuen-Shan Tsang et al.   JOURNAL OF CLINICAL INVESTIGATION

Ex Vivo Generation of Human Alloantigen-Specific Regulatory T Cells from CD4posCD25high T Cells for Immunotherapy

(2008) Jorieke H. Peters et al.   PLoS One