Long-Term Control of Diabetes in Immunosuppressed Nonhuman Primates (NHP) by the Transplantation of Adult Porcine Islets

Pig-to-Monkey Islet Xenotransplantation Using Multi-Transgenic Pigs

(2014) R. Bottino et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Humanized cobra venom factor: Structure, activity, and therapeutic efficacy in preclinical disease models

(2014) Carl-Wilhelm Vogel et al.   MOLECULAR IMMUNOLOGY

The Role of the Alternative Complement Pathway in Early Graft Loss After Intraportal Porcine Islet Xenotransplantation

(2014) Hee Jung Kang et al.   TRANSPLANTATION

A Phase 1, Randomized Ascending Single-Dose Study of Antagonist Anti-Human CD40 ASKP1240 in Healthy Subjects

(2013) R. Goldwater et al.   AMERICAN JOURNAL OF TRANSPLANTATION

ASKP1240, a Fully Human Anti-CD40 Monoclonal Antibody, Prolongs Pancreatic Islet Allograft Survival in Nonhuman Primates

(2013) M. Watanabe et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Biologic Agents in Islet Transplantation

(2013) Boris Gala-Lopez et al.   Current Diabetes Reports

Limitations of the pig-to-non-human primate islet transplantation model

(2013) Martin Wijkstrom et al.   XENOTRANSPLANTATION

Toward clinical islet xenotransplantation - are revisions to the IXA guidelines warranted?

(2013) David K.C. Cooper et al.   XENOTRANSPLANTATION

Long-Term Hepatic Allograft Acceptance Based on CD40 Blockade by ASKP1240 in Nonhuman Primates

(2012) T. Oura et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Alternative Immunomodulatory Strategies for Xenotransplantation: CD40/154 Pathway-Sparing Regimens Promote Xenograft Survival

(2012) P. Thompson et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Clinical Islet Xenotransplantation: How Close Are We?

(2012) D. J. van der Windt et al.   DIABETES

Islet Xenotransplantation Using Gal-Deficient Neonatal Donors Improves Engraftment and Function

(2011) P. Thompson et al.   AMERICAN JOURNAL OF TRANSPLANTATION

CD40-Specific Costimulation Blockade Enhances Neonatal Porcine Islet Survival in Nonhuman Primates

(2011) P. Thompson et al.   AMERICAN JOURNAL OF TRANSPLANTATION

The Sequential Combination of a JNK Inhibitor and Simvastatin Protects Porcine Islets from Peritransplant Apoptosis and Inflammation

(2011) Sang-Man Jin et al.   CELL TRANSPLANTATION

Pig-to-Nonhuman Primates Pancreatic Islet Xenotransplantation: An Overview

(2011) Marco Marigliano et al.   Current Diabetes Reports

In situ induction of dendritic cell–based T cell tolerance in humanized mice and nonhuman primates

(2011) Kyeong Cheon Jung et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Islet isolation from adult designated pathogen-free pigs: use of the newer bovine nervous tissue-free enzymes and a revised donor selection strategy would improve the islet graft function

(2011) Sang-Man Jin et al.   XENOTRANSPLANTATION

CD8+ regulatory T cells in solid organ transplantation

(2010) Carole Guillonneau et al.   Current Opinion in Organ Transplantation

A Novel Clinically Relevant Approach to Tip the Balance Toward Regulation in Stringent Transplant Model

(2010) Francesca DʼAddio et al.   TRANSPLANTATION

Long-Term Controlled Normoglycemia in Diabetic Non-Human Primates After Transplantation with hCD46 Transgenic Porcine Islets

(2009) D. J. van der Windt et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Effect of in vitroexpanded CD4+CD25+Foxp3+ regulatory T cell therapy combined with lymphodepletion in murine skin allotransplantation

(2009) Youn-Hee Park et al.   CLINICAL IMMUNOLOGY

Chapter 4: Pre-clinical efficacy and complication data required to justify a clinical trial

(2009) David K. C. Cooper et al.   XENOTRANSPLANTATION

Parameters for successful pig islet isolation as determined using 68 specific-pathogen-free miniature pigs

(2009) Hyoung-Il Kim et al.   XENOTRANSPLANTATION

Executive summary

(2009) Bernhard J. Hering et al.   XENOTRANSPLANTATION