PET and Optical Imaging of Caveolin-1 in Gastric Tumors

Mini-review: Antibody-PET of receptor tyrosine kinase interplay and heterogeneity

(2022) Anusha Chegu et al.   NUCLEAR MEDICINE AND BIOLOGY

Caveolin-1 temporal modulation enhances antibody drug efficacy in heterogeneous gastric cancer

(2022) Patrícia M. R. Pereira et al.   Nature Communications

ImmunoPET: Antibody-Based PET Imaging in Solid Tumors

(2022) Reyhaneh Manafi-Farid et al.   Frontiers in Medicine

Noninvasive assessment of human epidermal growth factor receptor 2 (HER2) in esophagogastric cancer using89Zr-trastuzumab PET: a pilot study

(2022) Melissa Amy Lumish et al.   JOURNAL OF NUCLEAR MEDICINE

Whole-body CD8+ T cell visualization before and during cancer immunotherapy: a phase 1/2 trial

(2022) Laura Kist de Ruijter et al.   NATURE MEDICINE

Impact of HER2 heterogeneity on treatment response of early-stage HER2-positive breast cancer: phase II neoadjuvant clinical trial of T-DM1 combined with pertuzumab

(2021) Otto Metzger Filho et al.   Cancer Discovery

Caveolin-1 and Sox-2 are predictive biomarkers of cetuximab response in head and neck cancer

(2021) Mehdi Bouhaddou et al.   JCI Insight

Hypoxia Attenuates Trastuzumab Uptake and Trastuzumab-Emtansine (T-DM1) Cytotoxicity Through Redistribution of Phosphorylated Caveolin-1

(2020) Vineesh Indira Chandran et al.   MOLECULAR CANCER RESEARCH

Caveolin-1 Promotes Chemoresistance of Gastric Cancer Cells to Cisplatin by Activating WNT/β-Catenin Pathway

(2020) Xi Wang et al.   Frontiers in Oncology

ImmunoPET: Concept, Design, and Applications

(2020) Weijun Wei et al.   CHEMICAL REVIEWS

Temporal Modulation of HER2 Membrane Availability Increases Pertuzumab Uptake and Pretargeted Molecular Imaging of Gastric Tumors

(2019) Patricia MR Pereira et al.   JOURNAL OF NUCLEAR MEDICINE

Cell Intrinsic and Extrinsic Mechanisms of Caveolin-1-Enhanced Metastasis

(2019) America Campos et al.   Biomolecules

Metformin-induced caveolin-1 expression promotes T-DM1 drug efficacy in breast cancer cells

(2018) Yuan-Chiang Chung et al.   Scientific Reports

An orthotopic mouse model of gastric cancer invasion and metastasis

(2018) Rita A. Busuttil et al.   Scientific Reports

Caveolin-1 mediates cellular distribution of HER2 and affects trastuzumab binding and therapeutic efficacy

(2018) Patrícia M. R. Pereira et al.   Nature Communications

Pharmacokinetics, Biodistribution, and Radiation Dosimetry for89Zr-Trastuzumab in Patients with Esophagogastric Cancer

(2017) Joseph A. O'Donoghue et al.   JOURNAL OF NUCLEAR MEDICINE

Caveolae-Mediated Endocytosis as a Novel Mechanism of Resistance to Trastuzumab Emtansine (T-DM1)

(2017) Matthew Sung et al.   MOLECULAR CANCER THERAPEUTICS

Downregulation of caveolin-1 increases the sensitivity of drug-resistant colorectal cancer HCT116 cells to 5-fluorouracil

(2016) Zhaoyang Li et al.   Oncology Letters

Molecular imaging as a tool to investigate heterogeneity of advanced HER2-positive breast cancer and to predict patient outcome under trastuzumab emtansine (T-DM1): the ZEPHIR trial

(2015) G. Gebhart et al.   ANNALS OF ONCOLOGY

Caveolin-1 mediates chemoresistance in cisplatin-resistant ovarian cancer cells by targeting apoptosis through the Notch-1/Akt/NF-κB pathway

(2015) WEI ZOU et al.   ONCOLOGY REPORTS

Early development of human lymphomas in a prostate cancer xenograft program using triple knock-out Immunocompromised mice

(2015) Christian Wetterauer et al.   PROSTATE

The Caveolin-1 Connection to Cell Death and Survival

(2013) A. F.G. Quest et al.   CURRENT MOLECULAR MEDICINE

starBase v2.0: decoding miRNA-ceRNA, miRNA-ncRNA and protein–RNA interaction networks from large-scale CLIP-Seq data

(2013) Jun-Hao Li et al.   NUCLEIC ACIDS RESEARCH

Identification of Caveolin-1 as a Potential Causative Factor in the Generation of Trastuzumab Resistance in Breast Cancer Cells

(2013) Sreeja C Sekhar et al.   Journal of Cancer

Human Solid Tumor Xenografts in Immunodeficient Mice Are Vulnerable to Lymphomagenesis Associated with Epstein-Barr Virus

(2012) Kui Chen et al.   PLoS One

RNA inference-mediated caveolin-1 down-regulation decrease estrogen receptor alpha (ERα) signaling in human mammary epithelial cells

(2010) Xi Wang et al.   MOLECULAR BIOLOGY REPORTS

Towards a knowledge-based Human Protein Atlas

(2010) Mathias Uhlen et al.   NATURE BIOTECHNOLOGY

RNA interference-directed caveolin-1 knockdown sensitizes SN12CPM6 cells to doxorubicin-induced apoptosis and reduces lung metastasis

(2010) Juwon Park et al.   TUMOR BIOLOGY