Caveolin-1 mediates cellular distribution of HER2 and affects trastuzumab binding and therapeutic efficacy
Published 2018 View Full Article
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Title
Caveolin-1 mediates cellular distribution of HER2 and affects trastuzumab binding and therapeutic efficacy
Authors
Keywords
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Journal
Nature Communications
Volume 9, Issue 1, Pages -
Publisher
Springer Nature
Online
2018-11-27
DOI
10.1038/s41467-018-07608-w
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Note: Only part of the references are listed.- Imaging of human epidermal growth factor receptors for patient selection and response monitoring – From PET imaging and beyond
- (2018) Patricia M.R. Pereira et al. CANCER LETTERS
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- (2018) Yuan-Chiang Chung et al. Scientific Reports
- Pharmacokinetics, Biodistribution, and Radiation Dosimetry for89Zr-Trastuzumab in Patients with Esophagogastric Cancer
- (2017) Joseph A. O'Donoghue et al. JOURNAL OF NUCLEAR MEDICINE
- Caveolae-Mediated Endocytosis as a Novel Mechanism of Resistance to Trastuzumab Emtansine (T-DM1)
- (2017) Matthew Sung et al. MOLECULAR CANCER THERAPEUTICS
- Genetic Predictors of Response to Systemic Therapy in Esophagogastric Cancer
- (2017) Yelena Y. Janjigian et al. Cancer Discovery
- Detection of HER2-Positive Metastases in Patients with HER2-Negative Primary Breast Cancer Using 89Zr-Trastuzumab PET/CT
- (2016) G. A. Ulaner et al. JOURNAL OF NUCLEAR MEDICINE
- HER2 expression identifies dynamic functional states within circulating breast cancer cells
- (2016) Nicole Vincent Jordan et al. NATURE
- Hypoxia regulates global membrane protein endocytosis through caveolin-1 in cancer cells
- (2016) E. Bourseau-Guilmain et al. Nature Communications
- Molecular imaging as a tool to investigate heterogeneity of advanced HER2-positive breast cancer and to predict patient outcome under trastuzumab emtansine (T-DM1): the ZEPHIR trial
- (2015) G. Gebhart et al. ANNALS OF ONCOLOGY
- HER2 expression status in diverse cancers: review of results from 37,992 patients
- (2015) Min Yan et al. CANCER AND METASTASIS REVIEWS
- β2-AR signaling controls trastuzumab resistance-dependent pathway
- (2015) D Liu et al. ONCOGENE
- mRNA Profiling Reveals Determinants of Trastuzumab Efficiency in HER2-Positive Breast Cancer
- (2015) Silvia von der Heyde et al. PLoS One
- Caveolin-1 Dependent Endocytosis Enhances the Chemosensitivity of HER-2 Positive Breast Cancer Cells to Trastuzumab Emtansine (T-DM1)
- (2015) Yuan-Chiang Chung et al. PLoS One
- HER2 mediates epidermal growth factor-induced down-regulation of E-cadherin in human ovarian cancer cells
- (2013) Jung-Chien Cheng et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- HER2 discordance between primary and metastatic breast cancer: Assessing the clinical impact
- (2013) Natalie H. Turner et al. CANCER TREATMENT REVIEWS
- Recommendations for Human Epidermal Growth Factor Receptor 2 Testing in Breast Cancer: American Society of Clinical Oncology/College of American Pathologists Clinical Practice Guideline Update
- (2013) Antonio C. Wolff et al. JOURNAL OF CLINICAL ONCOLOGY
- Monitoring Afatinib Treatment in HER2-Positive Gastric Cancer with 18F-FDG and 89Zr-Trastuzumab PET
- (2013) Y. Y. Janjigian et al. JOURNAL OF NUCLEAR MEDICINE
- Targeting the MUC1-C oncoprotein downregulates HER2 activation and abrogates trastuzumab resistance in breast cancer cells
- (2013) D Raina et al. ONCOGENE
- Identification of Caveolin-1 as a Potential Causative Factor in the Generation of Trastuzumab Resistance in Breast Cancer Cells
- (2013) Sreeja C Sekhar et al. Journal of Cancer
- Clinically Used Breast Cancer Markers Such As Estrogen Receptor, Progesterone Receptor, and Human Epidermal Growth Factor Receptor 2 Are Unstable Throughout Tumor Progression
- (2012) Linda Sofie Lindström et al. JOURNAL OF CLINICAL ONCOLOGY
- The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity
- (2012) Jordi Barretina et al. NATURE
- Targeting C4-Demethylating Genes in the Cholesterol Pathway Sensitizes Cancer Cells to EGF Receptor Inhibitors via Increased EGF Receptor Degradation
- (2012) Anna Sukhanova et al. Cancer Discovery
- HER2 shedding and serum HER2 extracellular domain: Biology and clinical utility in breast cancer
- (2011) Chantal Tsé et al. CANCER TREATMENT REVIEWS
- Loss of Human Epidermal Growth Factor Receptor 2 (HER2) Expression in Metastatic Sites of HER2-Overexpressing Primary Breast Tumors
- (2011) Naoki Niikura et al. JOURNAL OF CLINICAL ONCOLOGY
- ErbB2 Trafficking and Degradation Associated with K48 and K63 Polyubiquitination
- (2010) Corina Marx et al. CANCER RESEARCH
- Biodistribution of 89Zr-trastuzumab and PET Imaging of HER2-Positive Lesions in Patients With Metastatic Breast Cancer
- (2010) E C Dijkers et al. CLINICAL PHARMACOLOGY & THERAPEUTICS
- Antitumor Effects and Normal-Tissue Toxicity of 111In-Nuclear Localization Sequence-Trastuzumab in Athymic Mice Bearing HER-Positive Human Breast Cancer Xenografts
- (2010) D. L. Costantini et al. JOURNAL OF NUCLEAR MEDICINE
- Nuclear trafficking of the epidermal growth factor receptor family membrane proteins
- (2010) Y-N Wang et al. ONCOGENE
- Preclinical model of organotypic culture for pharmacodynamic profiling of human tumors
- (2010) V. Vaira et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Standardized methods for the production of high specific-activity zirconium-89
- (2009) Jason P. Holland et al. NUCLEAR MEDICINE AND BIOLOGY
- Endocytosis and intracellular trafficking of ErbBs
- (2008) Alexander Sorkin et al. EXPERIMENTAL CELL RESEARCH
- Endocytic downregulation of ErbB receptors: mechanisms and relevance in cancer
- (2008) Kirstine Roepstorff et al. HISTOCHEMISTRY AND CELL BIOLOGY
- Caveolin-1: A tumor-promoting role in human cancer
- (2008) Maria Shatz et al. INTERNATIONAL JOURNAL OF RADIATION BIOLOGY
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