Where and when to start: Regulating DNA replication origin activity in eukaryotic genomes

Single-copy locus proteomics of early- and late-firing DNA replication origins identifies a role of Ask1/DASH complex in replication timing control

(2023) Matthias Weiβ et al.   Cell Reports

Establishment and function of chromatin organization at replication origins

(2023) Erika Chacin et al.   NATURE

The Initiation of Eukaryotic DNA Replication

(2022) Alessandro Costa et al.   Annual Review of Biochemistry

Histone post-translational modifications — cause and consequence of genome function

(2022) Gonzalo Millán-Zambrano et al.   NATURE REVIEWS GENETICS

Mobile origin-licensing factors confer resistance to conflicts with RNA polymerase

(2022) Matthias J. Scherr et al.   Cell Reports

Yeast ORC sumoylation status fine-tunes origin licensing

(2022) Gemma Regan-Mochrie et al.   GENES & DEVELOPMENT

Determination of human DNA replication origin position and efficiency reveals principles of initiation zone organisation

(2022) Guillaume Guilbaud et al.   NUCLEIC ACIDS RESEARCH

Rpd3 regulates single-copy origins independently of the rDNA array by opposing Fkh1-mediated origin stimulation

(2022) Yiwei He et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Nucleosome-directed replication origin licensing independent of a consensus DNA sequence

(2022) Sai Li et al.   Nature Communications

Humanizing the yeast origin recognition complex

(2021) Clare S. K. Lee et al.   Nature Communications

Human ORC/MCM density is low in active genes and correlates with replication time but does not delimit initiation zones

(2021) Nina Kirstein et al.   eLife

Methylation of histone H3 at lysine 37 by Set1 and Set2 prevents spurious DNA replication

(2021) Helena Santos-Rosa et al.   MOLECULAR CELL

The capacity of origins to load MCM establishes replication timing patterns

(2021) Livio Dukaj et al.   PLoS Genetics

The Active Mechanism of Nucleosome Depletion by Poly(dA:dT) Tracts In Vivo

(2021) Toby Barnes et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Genome-wide mapping of human DNA replication by optical replication mapping supports a stochastic model of eukaryotic replication

(2021) Weitao Wang et al.   MOLECULAR CELL

Chromosomal Mcm2-7 distribution and the genome replication program in species from yeast to humans

(2021) Eric J. Foss et al.   PLoS Genetics

The genetic architecture of DNA replication timing in human pluripotent stem cells

(2021) Qiliang Ding et al.   Nature Communications

Sir2 mitigates an intrinsic imbalance in origin licensing efficiency between early- and late-replicating euchromatin

(2020) Timothy Hoggard et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A predictable conserved DNA base composition signature defines human core DNA replication origins

(2020) Ildem Akerman et al.   Nature Communications

Capturing the dynamics of genome replication on individual ultra-long nanopore sequence reads

(2019) Carolin A. Müller et al.   NATURE METHODS

Dynamic relocalization of replication origins by Fkh1 requires execution of DDK function and Cdc45 loading at origins

(2019) Haiyang Zhang et al.   eLife

Involvement of G-quadruplex regions in mammalian replication origin activity

(2019) Paulina Prorok et al.   Nature Communications

Origins of DNA replication

(2019) Babatunde Ekundayo et al.   PLoS Genetics

H2A.Z facilitates licensing and activation of early replication origins

(2019) Haizhen Long et al.   NATURE

Prediction of replication sites in Saccharomyces cerevisiae genome using DNA segment properties: Multi-view ensemble learning (MEL) approach

(2018) Vinod Kumar Singh et al.   BIOSYSTEMS

Oligomer formation and G-quadruplex binding by purified murine Rif1 protein, a key organizer of higher-order chromatin architecture

(2018) Kenji Moriyama et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Correlative live and super-resolution imaging reveals the dynamic structure of replication domains

(2018) Wanqing Xiang et al.   JOURNAL OF CELL BIOLOGY

The replication initiation determinant protein (RepID) modulates replication by recruiting CUL4 to chromatin

(2018) Sang-Min Jang et al.   Nature Communications

Rif1 Binding and Control of Chromosome-Internal DNA Replication Origins Is Limited by Telomere Sequestration

(2018) Lukas Hafner et al.   Cell Reports

Yeast heterochromatin regulators Sir2 and Sir3 act directly at euchromatic DNA replication origins

(2018) Timothy A. Hoggard et al.   PLoS Genetics

Dual Roles of Poly(dA:dT) Tracts in Replication Initiation and Fork Collapse

(2018) Anthony Tubbs et al.   CELL

Structure of the origin recognition complex bound to DNA replication origin

(2018) Ningning Li et al.   NATURE

Intragenic origins due to short G1 phases underlie oncogene-induced DNA replication stress

(2018) Morgane Macheret et al.   NATURE

Identify origin of replication in Saccharomyces cerevisiae using two-step feature selection technique

(2018) Fu-Ying Dao et al.   BIOINFORMATICS

Identifying cis Elements for Spatiotemporal Control of Mammalian DNA Replication

(2018) Jiao Sima et al.   CELL

Both a unique motif at the C terminus and N-terminal HEAT repeat contribute to G4 binding and origin regulation by Rif1 protein

(2018) Shunsuke Kobayashi et al.   MOLECULAR AND CELLULAR BIOLOGY

Dbf4 recruitment by forkhead transcription factors defines an upstream rate-limiting step in determining origin firing timing

(2017) Dingqiang Fang et al.   GENES & DEVELOPMENT

Chromatin Controls DNA Replication Origin Selection, Lagging-Strand Synthesis, and Replication Fork Rates

(2017) Christoph F. Kurat et al.   MOLECULAR CELL

Chromatin Constrains the Initiation and Elongation of DNA Replication

(2017) Sujan Devbhandari et al.   MOLECULAR CELL

How the Eukaryotic Replisome Achieves Rapid and Efficient DNA Replication

(2017) Joseph T.P. Yeeles et al.   MOLECULAR CELL

The gastrula transition reorganizes replication-origin selection in Caenorhabditis elegans

(2017) Marta Rodríguez-Martínez et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Structural basis of Mcm2–7 replicative helicase loading by ORC–Cdc6 and Cdt1

(2017) Zuanning Yuan et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

SIR2suppresses replication gaps and genome instability by balancing replication between repetitive and unique sequences

(2017) Eric J. Foss et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Conserved forkhead dimerization motif controls DNA replication timing and spatial organization of chromosomes inS. cerevisiae

(2017) A. Zachary Ostrow et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Bidirectional eukaryotic DNA replication is established by quasi-symmetrical helicase loading

(2017) Gideon Coster et al.   SCIENCE

Mechanisms for initiating cellular DNA replication

(2017) Franziska Bleichert et al.   SCIENCE

The gastrula transition reorganizes replication-origin selection in Caenorhabditis elegans

(2017) Marta Rodríguez-Martínez et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Structural basis of Mcm2–7 replicative helicase loading by ORC–Cdc6 and Cdt1

(2017) Zuanning Yuan et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Nucleosomes influence multiple steps during replication initiation

(2017) Ishara F Azmi et al.   eLife

Regulation of DNA Replication in Early Embryonic Cleavages

(2017) Chames Kermi et al.   Genes

Diversity of DNA Replication in the Archaea

(2017) Darya Ausiannikava et al.   Genes

Spatio-temporal re-organization of replication foci accompanies replication domain consolidation during human pluripotent stem cell lineage specification

(2016) Korey A. Wilson et al.   CELL CYCLE

How to rule the nucleus: divide et impera

(2016) Irina Solovei et al.   CURRENT OPINION IN CELL BIOLOGY

DNA replication origins—where do we begin?

(2016) Marie-Noëlle Prioleau et al.   GENES & DEVELOPMENT

Chromosome Duplication in Saccharomyces cerevisiae

(2016) S. P. Bell et al.   GENETICS

Quantitative BrdU immunoprecipitation method demonstrates that Fkh1 and Fkh2 are rate-limiting activators of replication origins that reprogram replication timing in G1 phase

(2016) Jared M. Peace et al.   GENOME RESEARCH

Nucleosome occupancy as a novel chromatin parameter for replication origin functions

(2016) Jairo Rodriguez et al.   GENOME RESEARCH

Replicating Large Genomes: Divide and Conquer

(2016) Juan Carlos Rivera-Mulia et al.   MOLECULAR CELL

The nature of mutations induced by replication–transcription collisions

(2016) T. Sabari Sankar et al.   NATURE

Transcription–replication conflicts: how they occur and how they are resolved

(2016) Tatiana García-Muse et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

H3K9me3 demethylase Kdm4d facilitates the formation of pre-initiative complex and regulates DNA replication

(2016) Rentian Wu et al.   NUCLEIC ACIDS RESEARCH

Genome-wide identification and characterisation of human DNA replication origins by initiation site sequencing (ini-seq)

(2016) Alexander R. Langley et al.   NUCLEIC ACIDS RESEARCH

Selectivity of ORC binding sites and the relation to replication timing, fragile sites, and deletions in cancers

(2016) Benoit Miotto et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

G-Quadruplexes in DNA Replication: A Problem or a Necessity?

(2016) Anne-Laure Valton et al.   TRENDS IN GENETICS

A replicator-specific binding protein essential for site-specific initiation of DNA replication in mammalian cells

(2016) Ya Zhang et al.   Nature Communications

4D Visualization of replication foci in mammalian cells corresponding to individual replicons

(2016) V. O. Chagin et al.   Nature Communications

Budding Yeast Rif1 Controls Genome Integrity by Inhibiting rDNA Replication

(2016) Maksym Shyian et al.   PLoS Genetics

Spatiotemporal coupling and decoupling of gene transcription with DNA replication origins during embryogenesis in C. elegans

(2016) Ehsan Pourkarimi et al.   eLife

SnapShot: Origins of DNA Replication

(2015) Rachel L. Creager et al.   CELL

BRPF3-HBO1 regulates replication origin activation and histone H3K14 acetylation

(2015) Y. Feng et al.   EMBO JOURNAL

Dynamic loading and redistribution of the Mcm2-7 helicase complex through the cell cycle

(2015) S. K. Powell et al.   EMBO JOURNAL

Genome-wide chromatin footprinting reveals changes in replication origin architecture induced by pre-RC assembly

(2015) Jason A. Belsky et al.   GENES & DEVELOPMENT

The chromatin environment shapes DNA replication origin organization and defines origin classes

(2015) Christelle Cayrou et al.   GENOME RESEARCH

Dynamic changes in replication timing and gene expression during lineage specification of human pluripotent stem cells

(2015) Juan Carlos Rivera-Mulia et al.   GENOME RESEARCH

Replication timing is regulated by the number of MCMs loaded at origins

(2015) Shankar P. Das et al.   GENOME RESEARCH

Post-licensing Specification of Eukaryotic Replication Origins by Facilitated Mcm2-7 Sliding along DNA

(2015) Julien Gros et al.   MOLECULAR CELL

Regulated eukaryotic DNA replication origin firing with purified proteins

(2015) Joseph T. P. Yeeles et al.   NATURE

DNA replication origin activation in space and time

(2015) Michalis Fragkos et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

DNA sequence templates adjacent nucleosome and ORC sites at gene amplification origins inDrosophila

(2015) Jun Liu et al.   NUCLEIC ACIDS RESEARCH

H3K4me3 demethylation by the histone demethylase KDM5C/JARID1C promotes DNA replication origin firing

(2015) Beatrice Rondinelli et al.   NUCLEIC ACIDS RESEARCH

CTCF establishes discrete functional chromatin domains at theHoxclusters during differentiation

(2015) Varun Narendra et al.   SCIENCE

High-Resolution Profiling of Drosophila Replication Start Sites Reveals a DNA Shape and Chromatin Signature of Metazoan Origins

(2015) Federico Comoglio et al.   Cell Reports

oriC-encoded instructions for the initiation of bacterial chromosome replication

(2015) Marcin WolaÅ„ski et al.   Frontiers in Microbiology

Different nucleosomal architectures at early and late replicating origins in Saccharomyces cerevisiae

(2014) Ignacio Soriano et al.   BMC GENOMICS

Genetic Variation in Human DNA Replication Timing

(2014) Amnon Koren et al.   CELL

Replication initiation and genome instability: a crossroads for DNA and RNA synthesis

(2014) Jacqueline H. Barlow et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

G4 motifs affect origin positioning and efficiency in two vertebrate replicators

(2014) A.-L. Valton et al.   EMBO JOURNAL

Rif1 controls DNA replication by directing Protein Phosphatase 1 to reverse Cdc7-mediated phosphorylation of the MCM complex

(2014) S.-i. Hiraga et al.   GENES & DEVELOPMENT

Chromatin Structure and Replication Origins: Determinants of Chromosome Replication and Nuclear Organization

(2014) Owen K. Smith et al.   JOURNAL OF MOLECULAR BIOLOGY

The Histone Deacetylases Sir2 and Rpd3 Act on Ribosomal DNA to Control the Replication Program in Budding Yeast

(2014) Kazumasa Yoshida et al.   MOLECULAR CELL

Topologically associating domains are stable units of replication-timing regulation

(2014) Benjamin D. Pope et al.   NATURE

Fkh1 and Fkh2 Bind Multiple Chromosomal Elements in the S. cerevisiae Genome with Distinct Specificities and Cell Cycle Dynamics

(2014) A. Zachary Ostrow et al.   PLoS One

Rif1 Regulates Initiation Timing of Late Replication Origins throughout the S. cerevisiae Genome

(2014) Jared M. Peace et al.   PLoS One

Protein Phosphatase 1 Recruitment by Rif1 Regulates DNA Replication Origin Firing by Counteracting DDK Activity

(2014) Anoushka Davé et al.   Cell Reports

Rif1 Controls DNA Replication Timing in Yeast through the PP1 Phosphatase Glc7

(2014) Stefano Mattarocci et al.   Cell Reports

Allele-Specific Genome-wide Profiling in Human Primary Erythroblasts Reveal Replication Program Organization

(2014) Rituparna Mukhopadhyay et al.   PLoS Genetics

Genetic and epigenetic determinants of DNA replication origins, position and activation

(2013) Marcel Méchali et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

High-resolution analysis of DNA synthesis start sites and nucleosome architecture at efficient mammalian replication origins

(2013) Rodrigo Lombraña et al.   EMBO JOURNAL

Exchange of associated factors directs a switch in HBO1 acetyltransferase histone tail specificity

(2013) M.-E. Lalonde et al.   GENES & DEVELOPMENT

Human Origin Recognition Complex Binds Preferentially to G-quadruplex-preferable RNA and Single-stranded DNA

(2013) Shoko Hoshina et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Stochastic association of neighboring replicons creates replication factories in budding yeast

(2013) Nazan Saner et al.   JOURNAL OF CELL BIOLOGY

Kinetochores Coordinate Pericentromeric Cohesion and Early DNA Replication by Cdc7-Dbf4 Kinase Recruitment

(2013) Toyoaki Natsume et al.   MOLECULAR CELL

Titration of Four Replication Factors Is Essential for the Xenopus laevis Midblastula Transition

(2013) C. Collart et al.   SCIENCE

DNA Replication Timing

(2013) N. Rhind et al.   Cold Spring Harbor Perspectives in Biology

DNA Replication Origins

(2013) A. C. Leonard et al.   Cold Spring Harbor Perspectives in Biology

High-Resolution Replication Profiles Define the Stochastic Nature of Genome Replication Initiation and Termination

(2013) Michelle Hawkins et al.   Cell Reports

Differential Relationship of DNA Replication Timing to Different Forms of Human Mutation and Variation

(2012) Amnon Koren et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Forkhead Transcription Factors Establish Origin Timing and Long-Range Clustering in S. cerevisiae

(2012) Simon R.V. Knott et al.   CELL

New insights into replication origin characteristics in metazoans

(2012) Christelle Cayrou et al.   CELL CYCLE

Mouse Rif1 is a key regulator of the replication-timing programme in mammalian cells

(2012) Daniela Cornacchia et al.   EMBO JOURNAL

Rif1 regulates the replication timing domains on the human genome

(2012) Satoshi Yamazaki et al.   EMBO JOURNAL

Rif1 is a global regulator of timing of replication origin firing in fission yeast

(2012) M. Hayano et al.   GENES & DEVELOPMENT

DNA Replication Origin Function Is Promoted by H3K4 Di-methylation in Saccharomyces cerevisiae

(2012) L. F. Rizzardi et al.   GENETICS

Genome-wide mapping of human DNA-replication origins: Levels of transcription at ORC1 sites regulate origin selection and replication timing

(2012) G. I. Dellino et al.   GENOME RESEARCH

ChIP-seq guidelines and practices of the ENCODE and modENCODE consortia

(2012) S. G. Landt et al.   GENOME RESEARCH

Extensive DNA Damage-Induced Sumoylation Contributes to Replication and Repair and Acts in Addition to the Mec1 Checkpoint

(2012) Catherine A. Cremona et al.   MOLECULAR CELL

Intrinsic coupling of lagging-strand synthesis to chromatin assembly

(2012) Duncan J. Smith et al.   NATURE

The BAH domain of ORC1 links H4K20me2 to DNA replication licensing and Meier–Gorlin syndrome

(2012) Alex J. Kuo et al.   NATURE

Topological domains in mammalian genomes identified by analysis of chromatin interactions

(2012) Jesse R. Dixon et al.   NATURE

Genome mapping on nanochannel arrays for structural variation analysis and sequence assembly

(2012) Ernest T Lam et al.   NATURE BIOTECHNOLOGY

Unraveling cell type–specific and reprogrammable human replication origin signatures associated with G-quadruplex consensus motifs

(2012) Emilie Besnard et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Regulation of DNA Replication within the Immunoglobulin Heavy-Chain Locus During B Cell Commitment

(2012) Agnieszka Demczuk et al.   PLOS BIOLOGY

Origin Association of Sld3, Sld7, and Cdc45 Proteins Is a Key Step for Determination of Origin-Firing Timing

(2011) Seiji Tanaka et al.   CURRENT BIOLOGY

Limiting replication initiation factors execute the temporal programme of origin firing in budding yeast

(2011) Davide Mantiero et al.   EMBO JOURNAL

Genome-wide depletion of replication initiation events in highly transcribed regions

(2011) M. M. Martin et al.   GENOME RESEARCH

Genome-scale analysis of metazoan replication origins reveals their organization in specific but flexible sites defined by conserved features

(2011) C. Cayrou et al.   GENOME RESEARCH

The effect of Ku on telomere replication time is mediated by telomere length but is independent of histone tail acetylation

(2011) Hui-Yong Lian et al.   MOLECULAR BIOLOGY OF THE CELL

To promote and protect: Coordinating DNA replication and transcription for genome stability

(2010) Simon R.V. Knott et al.   Epigenetics

Conserved nucleosome positioning defines replication origins

(2010) M. L. Eaton et al.   GENES & DEVELOPMENT

Evolutionarily conserved replication timing profiles predict long-range chromatin interactions and distinguish closely related cell types

(2010) T. Ryba et al.   GENOME RESEARCH

Chromatin signatures of the Drosophila replication program

(2010) M. L. Eaton et al.   GENOME RESEARCH

Early initiation of a replication origin tethered at the nuclear periphery

(2010) H. Ebrahimi et al.   JOURNAL OF CELL SCIENCE

Guanine quadruplex DNA structure restricts methylation of CpG dinucleotides genome-wide

(2010) Rashi Halder et al.   Molecular BioSystems

HBO1 Histone Acetylase Activity Is Essential for DNA Replication Licensing and Inhibited by Geminin

(2010) Benoit Miotto et al.   MOLECULAR CELL

Molecular Maps of the Reorganization of Genome-Nuclear Lamina Interactions during Differentiation

(2010) Daan Peric-Hupkes et al.   MOLECULAR CELL

A three-dimensional model of the yeast genome

(2010) Zhijun Duan et al.   NATURE

The histone H4 Lys 20 methyltransferase PR-Set7 regulates replication origins in mammalian cells

(2010) Mathieu Tardat et al.   NATURE CELL BIOLOGY

Dynamic changes in histone acetylation regulate origins of DNA replication

(2010) Ashwin Unnikrishnan et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Pre-replication complex proteins assemble at regions of low nucleosome occupancy within the Chinese hamster dihydrofolate reductase initiation zone

(2010) Yoav Lubelsky et al.   NUCLEIC ACIDS RESEARCH

Extensive role of the general regulatory factors, Abf1 and Rap1, in determining genome-wide chromatin structure in budding yeast

(2010) Mythily Ganapathi et al.   NUCLEIC ACIDS RESEARCH

Diversity of Eukaryotic DNA Replication Origins Revealed by Genome-Wide Analysis of Chromatin Structure

(2010) Nicolas M. Berbenetz et al.   PLoS Genetics

The impact of nucleosome positioning on the organization of replication origins in eukaryotes

(2009) Shanye Yin et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Spatial regulation and organization of DNA replication within the nucleus

(2009) Toyoaki Natsume et al.   CHROMOSOME RESEARCH

Genome-wide replication profiles indicate an expansive role for Rpd3L in regulating replication initiation timing or efficiency, and reveal genomic loci of Rpd3 function in Saccharomyces cerevisiae

(2009) S. R.V. Knott et al.   GENES & DEVELOPMENT

Drosophila ORC localizes to open chromatin and marks sites of cohesin complex loading

(2009) H. K. MacAlpine et al.   GENOME RESEARCH

Genome-wide analysis predicts DNA structural motifs as nucleosome exclusion signals

(2009) Kangkan Halder et al.   Molecular BioSystems

Highly Transcribed RNA Polymerase II Genes Are Impediments to Replication Fork Progression in Saccharomyces cerevisiae

(2009) Anna Azvolinsky et al.   MOLECULAR CELL

Human mutation rate associated with DNA replication timing

(2009) John A Stamatoyannopoulos et al.   NATURE GENETICS

H3 K36 Methylation Helps Determine the Timing of Cdc45 Association with Replication Origins

(2009) Fiona Pryde et al.   PLoS One

Sequencing newly replicated DNA reveals widespread plasticity in human replication timing

(2009) R. S. Hansen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Orc1 Controls Centriole and Centrosome Copy Number in Human Cells

(2009) A. S. Hemerly et al.   SCIENCE

Comprehensive Mapping of Long-Range Interactions Reveals Folding Principles of the Human Genome

(2009) E. Lieberman-Aiden et al.   SCIENCE

System-Wide Changes to SUMO Modifications in Response to Heat Shock

(2009) F. Golebiowski et al.   Science Signaling

Transcription Initiation Activity Sets Replication Origin Efficiency in Mammalian Cells

(2009) Joana Sequeira-Mendes et al.   PLoS Genetics

DNA replication timing of the human  -globin domain is controlled by histone modification at the origin

(2008) A. Goren et al.   GENES & DEVELOPMENT

Analysis of Chromosome III Replicators Reveals an Unusual Structure for the ARS318 Silencer Origin and a Conserved WTW Sequence within the Origin Recognition Complex Binding Site

(2008) F. Chang et al.   MOLECULAR AND CELLULAR BIOLOGY

Nucleosome organization in the Drosophila genome

(2008) Travis N. Mavrich et al.   NATURE

Genome-wide studies highlight indirect links between human replication origins and gene regulation

(2008) J.-C. Cadoret et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Global Reorganization of Replication Domains During Embryonic Stem Cell Differentiation

(2008) Ichiro Hiratani et al.   PLOS BIOLOGY

Distinct Modes of Regulation by Chromatin Encoded through Nucleosome Positioning Signals

(2008) Yair Field et al.   PLoS Computational Biology

DNA Combing Reveals Intrinsic Temporal Disorder in the Replication of Yeast Chromosome VI

(2007) Daniel M. Czajkowsky et al.   JOURNAL OF MOLECULAR BIOLOGY