Dbf4 recruitment by forkhead transcription factors defines an upstream rate-limiting step in determining origin firing timing

Conserved forkhead dimerization motif controls DNA replication timing and spatial organization of chromosomes inS. cerevisiae

(2017) A. Zachary Ostrow et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Phosphopeptide binding by Sld3 links Dbf4‐dependent kinase to MCM replicative helicase activation

(2016) Tom D Deegan et al.   EMBO JOURNAL

Concerted activities of Mcm4, Sld3, and Dbf4 in control of origin activation and DNA replication fork progression

(2016) Yi-Jun Sheu et al.   GENOME RESEARCH

Quantitative BrdU immunoprecipitation method demonstrates that Fkh1 and Fkh2 are rate-limiting activators of replication origins that reprogram replication timing in G1 phase

(2016) Jared M. Peace et al.   GENOME RESEARCH

Single-Molecule Studies of Origin Licensing Reveal Mechanisms Ensuring Bidirectional Helicase Loading

(2015) Simina Ticau et al.   CELL

The Replication Initiation Protein Sld3/Treslin Orchestrates the Assembly of the Replication Fork Helicase during S Phase

(2015) Irina Bruck et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Dynamics of Eukaryotic Replication Initiation: Origin Specificity, Licensing, and Firing at the Single-Molecule Level

(2015) Daniel Duzdevich et al.   MOLECULAR CELL

DNA replication origin activation in space and time

(2015) Michalis Fragkos et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Cell-Cycle-Regulated Interaction between Mcm10 and Double Hexameric Mcm2-7 Is Required for Helicase Splitting and Activation during S Phase

(2015) Yun Quan et al.   Cell Reports

Rif1 controls DNA replication by directing Protein Phosphatase 1 to reverse Cdc7-mediated phosphorylation of the MCM complex

(2014) S.-i. Hiraga et al.   GENES & DEVELOPMENT

The Histone Deacetylases Sir2 and Rpd3 Act on Ribosomal DNA to Control the Replication Program in Budding Yeast

(2014) Kazumasa Yoshida et al.   MOLECULAR CELL

Protein Phosphatase 1 Recruitment by Rif1 Regulates DNA Replication Origin Firing by Counteracting DDK Activity

(2014) Anoushka Davé et al.   Cell Reports

Rif1 Controls DNA Replication Timing in Yeast through the PP1 Phosphatase Glc7

(2014) Stefano Mattarocci et al.   Cell Reports

Loading and activation of DNA replicative helicases: the key step of initiation of DNA replication

(2013) Yan Li et al.   GENES TO CELLS

Dbf4 and Cdc7 Proteins Promote DNA Replication through Interactions with Distinct Mcm2–7 Protein Subunits

(2013) Matthew D. Ramer et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Stochastic association of neighboring replicons creates replication factories in budding yeast

(2013) Nazan Saner et al.   JOURNAL OF CELL BIOLOGY

Time to Be Versatile: Regulation of the Replication Timing Program in Budding Yeast

(2013) Kazumasa Yoshida et al.   JOURNAL OF MOLECULAR BIOLOGY

Kinetochores Coordinate Pericentromeric Cohesion and Early DNA Replication by Cdc7-Dbf4 Kinase Recruitment

(2013) Toyoaki Natsume et al.   MOLECULAR CELL

The dynamics of genome replication using deep sequencing

(2013) Carolin A. Müller et al.   NUCLEIC ACIDS RESEARCH

DNA Replication Timing

(2013) N. Rhind et al.   Cold Spring Harbor Perspectives in Biology

Helicase Loading at Chromosomal Origins of Replication

(2013) S. P. Bell et al.   Cold Spring Harbor Perspectives in Biology

Forkhead Transcription Factors Establish Origin Timing and Long-Range Clustering in S. cerevisiae

(2012) Simon R.V. Knott et al.   CELL

Replication Timing: The Early Bird Catches the Worm

(2012) Max E. Douglas et al.   CURRENT BIOLOGY

dNTP pools determine fork progression and origin usage under replication stress

(2012) Jérôme Poli et al.   EMBO JOURNAL

Mouse Rif1 is a key regulator of the replication-timing programme in mammalian cells

(2012) Daniela Cornacchia et al.   EMBO JOURNAL

Rif1 regulates the replication timing domains on the human genome

(2012) Satoshi Yamazaki et al.   EMBO JOURNAL

Rif1 is a global regulator of timing of replication origin firing in fission yeast

(2012) M. Hayano et al.   GENES & DEVELOPMENT

Regulation of Budding Yeast Mating-Type Switching Donor Preference by the FHA Domain of Fkh1

(2012) Jin Li et al.   PLoS Genetics

Eukaryotic Origin-Dependent DNA Replication In Vitro Reveals Sequential Action of DDK and S-CDK Kinases

(2011) Ryan C. Heller et al.   CELL

Origin Association of Sld3, Sld7, and Cdc45 Proteins Is a Key Step for Determination of Origin-Firing Timing

(2011) Seiji Tanaka et al.   CURRENT BIOLOGY

Limiting replication initiation factors execute the temporal programme of origin firing in budding yeast

(2011) Davide Mantiero et al.   EMBO JOURNAL

Eukaryotic Chromosome DNA Replication: Where, When, and How?

(2010) Hisao Masai et al.   Annual Review of Biochemistry

The Dbf4 motif C zinc finger promotes DNA replication and mediates resistance to genotoxic stress

(2010) Darryl R. Jones et al.   CELL CYCLE

CDK-dependent complex formation between replication proteins Dpb11, Sld2, Pol  , and GINS in budding yeast

(2010) S. Muramatsu et al.   GENES & DEVELOPMENT

How do Cdc7 and cyclin-dependent kinases trigger the initiation of chromosome replication in eukaryotic cells?

(2010) K. Labib   GENES & DEVELOPMENT

Mec1 Is One of Multiple Kinases that Prime the Mcm2-7 Helicase for Phosphorylation by Cdc7

(2010) John C.W. Randell et al.   MOLECULAR CELL

The Dbf4–Cdc7 kinase promotes S phase by alleviating an inhibitory activity in Mcm4

(2010) Yi-Jun Sheu et al.   NATURE

Analysis of replication profiles reveals key role of RFC-Ctf18 in yeast replication stress response

(2010) Laure Crabbé et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The Integrated Genome Browser: free software for distribution and exploration of genome-scale datasets

(2009) J. W. Nicol et al.   BIOINFORMATICS

Eukaryotic DNA replication control: Lock and load, then fire

(2009) Dirk Remus et al.   CURRENT OPINION IN CELL BIOLOGY

Genome-wide replication profiles indicate an expansive role for Rpd3L in regulating replication initiation timing or efficiency, and reveal genomic loci of Rpd3 function in Saccharomyces cerevisiae

(2009) S. R.V. Knott et al.   GENES & DEVELOPMENT

Budding Yeast Dbf4 Sequences Required for Cdc7 Kinase Activation and Identification of a Functional Relationship Between the Dbf4 and Rev1 BRCT Domains

(2009) Victoria Harkins et al.   GENETICS

Replication timing and epigenetic reprogramming of gene expression: a two-way relationship?

(2009) Anita Göndör et al.   NATURE REVIEWS GENETICS

Mrc1 and DNA Polymerase ɛ Function Together in Linking DNA Replication and the S Phase Checkpoint

(2008) Huiqiang Lou et al.   MOLECULAR CELL