Human Origin Recognition Complex Binds Preferentially to G-quadruplex-preferable RNA and Single-stranded DNA

Co-transcriptional formation of DNA:RNA hybrid G-quadruplex and potential function as constitutional cis element for transcription control

(2013) Ke-wei Zheng et al.   NUCLEIC ACIDS RESEARCH

The G4 Genome

(2013) Nancy Maizels et al.   PLoS Genetics

New insights into replication origin characteristics in metazoans

(2012) Christelle Cayrou et al.   CELL CYCLE

Genome-wide mapping of human DNA-replication origins: Levels of transcription at ORC1 sites regulate origin selection and replication timing

(2012) G. I. Dellino et al.   GENOME RESEARCH

Epstein-Barr Nuclear Antigen 1 (EBNA1)-dependent Recruitment of Origin Recognition Complex (Orc) onoriPof Epstein-Barr Virus with Purified Proteins

(2012) Kenji Moriyama et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

R Loops: From Transcription Byproducts to Threats to Genome Stability

(2012) Andrés Aguilera et al.   MOLECULAR CELL

Unraveling cell type–specific and reprogrammable human replication origin signatures associated with G-quadruplex consensus motifs

(2012) Emilie Besnard et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Genome-wide depletion of replication initiation events in highly transcribed regions

(2011) M. M. Martin et al.   GENOME RESEARCH

Genome-scale analysis of metazoan replication origins reveals their organization in specific but flexible sites defined by conserved features

(2011) C. Cayrou et al.   GENOME RESEARCH

Preferential Localization of Human Origins of DNA Replication at the 5′-Ends of Expressed Genes and at Evolutionarily Conserved DNA Sequences

(2011) Manuel S. Valenzuela et al.   PLoS One

Structural analysis of human Orc6 protein reveals a homology with transcription factor TFIIB

(2011) S. Liu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Eukaryotic DNA replication origins: many choices for appropriate answers

(2010) Marcel Méchali   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Human origin recognition complex is essential for HP1 binding to chromatin and heterochromatin organization

(2010) S. G. Prasanth et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structure of DNMT1-DNA Complex Reveals a Role for Autoinhibition in Maintenance DNA Methylation

(2010) J. Song et al.   SCIENCE

Role for G-Quadruplex RNA Binding by Epstein-Barr Virus Nuclear Antigen 1 in DNA Replication and Metaphase Chromosome Attachment

(2009) J. Norseen et al.   JOURNAL OF VIROLOGY

Genomic Study of Replication Initiation in Human Chromosomes Reveals the Influence of Transcription Regulation and Chromatin Structure on Origin Selection

(2009) Neerja Karnani et al.   MOLECULAR BIOLOGY OF THE CELL

Human initiation protein Orc4 prefers triple stranded DNA

(2009) J. Kusic et al.   MOLECULAR BIOLOGY REPORTS

TERRA RNA Binding to TRF2 Facilitates Heterochromatin Formation and ORC Recruitment at Telomeres

(2009) Zhong Deng et al.   MOLECULAR CELL

Orc1 Controls Centriole and Centrosome Copy Number in Human Cells

(2009) A. S. Hemerly et al.   SCIENCE

Transcription Initiation Activity Sets Replication Origin Efficiency in Mammalian Cells

(2009) Joana Sequeira-Mendes et al.   PLoS Genetics

RNA-dependent recruitment of the origin recognition complex

(2008) Julie Norseen et al.   EMBO JOURNAL

Global organization of replication time zones of the mouse genome

(2008) S. Farkash-Amar et al.   GENOME RESEARCH

Interaction between HMGA1a and the origin recognition complex creates site-specific replication origins

(2008) A. W. Thomae et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mammalian DNA Methyltransferases: A Structural Perspective

(2008) Xiaodong Cheng et al.   STRUCTURE