In vitro activity and mechanism of cell death induction of cyanomethyl vinyl ethers derivatives against Trypanosoma cruzi

In vitro activity and cell death mechanism induced by acrylonitrile derivatives against Leishmania amazonensis

(2022) Carlos J. Bethencourt-Estrella et al.   BIOORGANIC CHEMISTRY

In Vitro Susceptibility of Kinetoplastids to Celastroloids from Maytenus chiapensis

(2021) Marvin J. Núñez et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Cyanovinylation of Aldehydes: Organocatalytic Multicomponent Synthesis of Conjugated Cyanomethyl Vinyl Ethers

(2021) Samuel Delgado-Hernández et al.   MOLECULES

Acrylonitrile Derivatives against Trypanosoma cruzi: In Vitro Activity and Programmed Cell Death Study

(2021) Carlos Bethencourt-Estrella et al.   Pharmaceuticals

Discovery of New Chemical Tools against Leishmania amazonensis via the MMV Pathogen Box

(2021) Atteneri López-Arencibia et al.   Pharmaceuticals

Assessing the effectiveness of AS-48 in experimental mice models of Chagas’ disease

(2020) Rubén Martín-Escolano et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Antikinetoplastid Activity of Indolocarbazoles from Streptomyces sanyensis

(2020) Luis Cartuche et al.   Biomolecules

Dipeptidyl nitrile derivatives suppress the Trypanosoma cruzi in vitro infection

(2020) José C. Quilles et al.   EXPERIMENTAL PARASITOLOGY

Synthesis, biochemical evaluation and molecular modeling studies of nonpeptidic nitrile-based fluorinated compounds

(2020) Rafael da Fonseca Lameiro et al.   Future Medicinal Chemistry

Cell death pathways in pathogenic trypanosomatids: lessons of (over)kill

(2019) Rubem Figueiredo Sadok Menna-Barreto   Cell Death & Disease

Further insights of selenium-containing analogues of WC-9 against Trypanosoma cruzi

(2019) María N. Chao et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Chagas disease as example of a reemerging parasite

(2019) Jeannette Guarner   SEMINARS IN DIAGNOSTIC PATHOLOGY

(De)glutamylation and cell death in Leishmania parasites

(2019) Louise Basmaciyan et al.   PLoS Neglected Tropical Diseases

Chagas Disease: Chronic Chagas Cardiomyopathy

(2019) Natalia Giraldo Echavarría et al.   CURRENT PROBLEMS IN CARDIOLOGY

In vitro activity of 1H-phenalen-1-one derivatives against Leishmania spp. and evidence of programmed cell death

(2019) Atteneri López-Arencibia et al.   Parasites & Vectors

Indole and Benzimidazole Bichalcophenes: Synthesis, DNA Binding and Antiparasitic Activity

(2018) Abdelbasset A. Farahat et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Activity in vitro and in vivo against Trypanosoma cruzi of a furofuran lignan isolated from Piper jericoense

(2018) Paola García-Huertas et al.   EXPERIMENTAL PARASITOLOGY

Chagas disease

(2018) José A Pérez-Molina et al.   LANCET

Circulating Plasma MicroRNA-208a as Potential Biomarker of Chronic Indeterminate Phase of Chagas Disease

(2018) Leandra Linhares-Lacerda et al.   Frontiers in Microbiology

Anti-trypanosomal activity of non-peptidic nitrile-based cysteine protease inhibitors

(2017) Antonio C. B. Burtoloso et al.   PLoS Neglected Tropical Diseases

Nitrotriazole-based acetamides and propanamides with broad spectrum antitrypanosomal activity

(2016) Maria V. Papadopoulou et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Dimeric Flavonoids from Arrabidaea brachypoda and Assessment of Their Anti-Trypanosoma cruzi Activity

(2014) Cláudia Quintino da Rocha et al.   JOURNAL OF NATURAL PRODUCTS

Design, structure–activity relationship and in vivo efficacy of piperazine analogues of fenarimol as inhibitors of Trypanosoma cruzi

(2013) Martine Keenan et al.   BIOORGANIC & MEDICINAL CHEMISTRY

American Trypanosomiasis (Chagas Disease)

(2012) Anis Rassi et al.   INFECTIOUS DISEASE CLINICS OF NORTH AMERICA

Antiplasmodial and Leishmanicidal Activities of 2-Cyano-3-(4-phenylpiperazine-1-carboxamido) Quinoxaline 1,4-Dioxide Derivatives

(2012) Carlos Barea et al.   MOLECULES

In Vitro and in Vivo Trypanocidal Activity of Flavonoids fromDelphinium staphisagriaagainst Chagas Disease

(2011) Clotilde Marín et al.   JOURNAL OF NATURAL PRODUCTS

Research needs for Chagas disease prevention

(2010) Fernando Abad-Franch et al.   ACTA TROPICA

Identification of potent and reversible cruzipain inhibitors for the treatment of Chagas disease

(2010) Christian Beaulieu et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Chagas disease

(2010) Anis Rassi et al.   LANCET

Specific chemotherapy of Chagas disease: Relevance, current limitations and new approaches

(2009) Julio A. Urbina   ACTA TROPICA

An Estimate of the Burden of Chagas Disease in the United States

(2009) Caryn Bern et al.   CLINICAL INFECTIOUS DISEASES

Challenges and opportunities for primary, secondary, and tertiary prevention of Chagas' disease

(2009) A Rassi et al.   HEART

Heterocyclic-2-carboxylic Acid (3-Cyano-1,4-di-N-oxidequinoxalin-2-yl)amide Derivatives as Hits for the Development of Neglected Disease Drugs

(2009) Saioa Ancizu et al.   MOLECULES