Discovery of New Chemical Tools against Leishmania amazonensis via the MMV Pathogen Box

Screening and Identification of Pathogen Box® Compounds with anti-Trypanosoma evansi Activity

(2020) Mariana Feltrin Canever et al.   ACTA TROPICA

Screening the Medicines for Malaria Venture Pathogen Box for invasion and egress inhibitors of the blood stage of Plasmodium falciparum reveals several inhibitory compounds

(2020) Madeline G. Dans et al.   INTERNATIONAL JOURNAL FOR PARASITOLOGY

Sesquiterpenoids and flavonoids from Inula viscosa induce programmed cell death in kinetoplastids

(2020) Ikrame Zeouk et al.   BIOMEDICINE & PHARMACOTHERAPY

Membrane dynamics in Leishmania amazonensis and antileishmanial activities of β-carboline derivatives

(2020) Lais Alonso et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Screening The Pathogen Box for Identification of New Chemicals Agents With Anti Fasciola hepatica Activity

(2019) Claudia Machicado et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Cell death pathways in pathogenic trypanosomatids: lessons of (over)kill

(2019) Rubem Figueiredo Sadok Menna-Barreto   Cell Death & Disease

Screening of the pathogen box for the identification of anti-Acanthamoeba agents

(2019) Ines Sifaoui et al.   EXPERIMENTAL PARASITOLOGY

Withanolides from Withania aristata as Antikinetoplastid Agents through Induction of Programmed Cell Death

(2019) López-Arencibia et al.   Pathogens

Antiprotozoal activities of marine polyether triterpenoids

(2019) Ana R. Díaz-Marrero et al.   BIOORGANIC CHEMISTRY

Leishmania amazonensis ferric iron reductase (LFR1) is a bifunctional enzyme: Unveiling a NADPH oxidase activity

(2019) N. Rocco-Machado et al.   FREE RADICAL BIOLOGY AND MEDICINE

Recent Advances in the Discovery of Novel Antiprotozoal Agents

(2019) Lee et al.   MOLECULES

In vitro activity of 1H-phenalen-1-one derivatives against Leishmania spp. and evidence of programmed cell death

(2019) Atteneri López-Arencibia et al.   Parasites & Vectors

Design, synthesis and evaluation of amino-substituted 1 H -phenalen-1-ones as anti-leishmanial agents

(2018) Mónica Blanco Freijo et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Drug resistance and treatment failure in leishmaniasis: A 21st century challenge

(2017) Alicia Ponte-Sucre et al.   PLoS Neglected Tropical Diseases

Efficacy of tamoxifen and miltefosine combined therapy for cutaneous leishmaniasis in the murine model of infection withLeishmania amazonensis

(2016) Cristiana T. Trinconi et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

In VitroActivities of Hexaazatrinaphthylenes against Leishmania spp.

(2015) Atteneri López-Arencibia et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Apoptosis, autophagy, necroptosis, and cancer metastasis

(2015) Zhenyi Su et al.   Molecular Cancer

The Calpain Inhibitor MDL28170 Induces the Expression of Apoptotic Markers in Leishmania amazonensis Promastigotes

(2014) Fernanda A. Marinho et al.   PLoS One

Activity of imidazole compounds on Leishmania (L.) infantum chagasi: reactive oxygen species induced by econazole

(2013) Juliana Tonini Mesquita et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Cell death in parasitic protozoa: regulated or incidental?

(2012) William R. Proto et al.   NATURE REVIEWS MICROBIOLOGY

The Crystal Structures of the Tryparedoxin-Tryparedoxin Peroxidase Couple Unveil the Structural Determinants of Leishmania Detoxification Pathway

(2012) Annarita Fiorillo et al.   PLoS Neglected Tropical Diseases

A Parasite Rescue and Transformation Assay for Antileishmanial Screening Against Intracellular Leishmania donovani Amastigotes in THP1 Human Acute Monocytic Leukemia Cell Line

(2012) Surendra K. Jain et al.   Jove-Journal of Visualized Experiments

Plant derived therapeutics for the treatment of Leishmaniasis

(2011) Rupashree Sen et al.   PHYTOMEDICINE

The Meaning of Death: Evolution and Ecology of Apoptosis in Protozoan Parasites

(2011) Sarah E. Reece et al.   PLoS Pathogens

Small-Molecule Inhibitors of NADPH Oxidase 4

(2010) Gábor Borbély et al.   JOURNAL OF MEDICINAL CHEMISTRY

Analysis of endogenous glutathione-adducts and their metabolites

(2009) Ian A. Blair   BIOMEDICAL CHROMATOGRAPHY

Synthesis and evaluation of 2-pyridyl pyrimidines with in vitro antiplasmodial and antileishmanial activity

(2008) Chitalu C. Musonda et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Mitochondria-Dependent Reactive Oxygen Species-Mediated Programmed Cell Death Induced by 3,3'-Diindolylmethane through Inhibition of F0F1-ATP Synthase in Unicellular Protozoan Parasite Leishmania donovani

(2008) A. Roy et al.   MOLECULAR PHARMACOLOGY

Gametogenesis in Malaria Parasites Is Mediated by the cGMP-Dependent Protein Kinase

(2008) Louisa McRobert et al.   PLOS BIOLOGY