In Vitro Susceptibility of Kinetoplastids to Celastroloids from Maytenus chiapensis

Phytochemicals and biological activities of species from the genus Maytenus

(2020) Lei Zhang et al.   MEDICINAL CHEMISTRY RESEARCH

Natural Products as Sources of New Drugs over the Nearly Four Decades from 01/1981 to 09/2019

(2020) David J. Newman et al.   JOURNAL OF NATURAL PRODUCTS

Sesquiterpenoids and flavonoids from Inula viscosa induce programmed cell death in kinetoplastids

(2020) Ikrame Zeouk et al.   BIOMEDICINE & PHARMACOTHERAPY

Chagas Disease: Current View of an Ancient and Global Chemotherapy Challenge

(2020) Javier Martín-Escolano et al.   ACS Infectious Diseases

Structural Requirements for Antimicrobial Activity of Phenolic Nor-Triterpenes from Celastraceae Species

(2019) Laila Moujir et al.   Applied Sciences-Basel

SAR study of celastrol analogs targeting Nur77-mediated inflammatory pathway

(2019) Ziwen Chen et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Withanolides from Withania aristata as Antikinetoplastid Agents through Induction of Programmed Cell Death

(2019) López-Arencibia et al.   Pathogens

Evaluation of the antileishmanial activity of biodegradable microparticles containing a hexanic eluate subfraction of Maytenus guianensis bark

(2019) Sharon Rose Aragão Macedo et al.   EXPERIMENTAL PARASITOLOGY

Why hasn’t there been more progress in new Chagas disease drug discovery?

(2019) Alane Beatriz Vermelho et al.   Expert Opinion on Drug Discovery

Recent advances in α,β-unsaturated carbonyl compounds as mitochondrial toxins

(2019) Mohammad Hossain et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Chagas disease

(2018) José A Pérez-Molina et al.   LANCET

In vitro plant tissue culture: means for production of biological active compounds

(2018) Claudia A. Espinosa-Leal et al.   PLANTA

Challenges in drug discovery targeting TriTryp diseases with an emphasis on leishmaniasis

(2018) Laura M. Alcântara et al.   International Journal for Parasitology-Drugs and Drug Resistance

Leishmaniasis: treatment, drug resistance and emerging therapies

(2018) Shyam Sundar et al.   Expert Opinion on Orphan Drugs

Drug Discovery for Kinetoplastid Diseases: Future Directions

(2018) Srinivasa P. S. Rao et al.   ACS Infectious Diseases

Applicability of plant-based products in the treatment of Trypanosoma cruzi and Trypanosoma brucei infections: a systematic review of preclinical in vivo evidence

(2017) RODRIGO M. PEREIRA et al.   PARASITOLOGY

ANTIPROTOZOAL ACTIVITY OF EXTRACTS OF ELAEODENDRON TRICHOTOMUM (CELASTRACEAE)

(2016) Carolina Roca-Mézquita et al.   African Journal of Traditional Complementary and Alternative Medicines

Current Therapeutics, Their Problems and Thiol Metabolism as Potential Drug Targets in Leishmaniasis

(2016) Kuljit Singh et al.   CURRENT DRUG METABOLISM

Dihydro-β-agarofuran sesquiterpenes from celastraceae species as anti-tumour-promoting agents: Structure-activity relationship

(2016) Marvin J. Núñez et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

The Role of Natural Products in Drug Discovery and Development against Neglected Tropical Diseases

(2016) Peter Cheuka et al.   MOLECULES

Screening of the in vitro antileishmanial activities of compounds and secondary metabolites isolated from Maytenus guianensis Klotzsch ex Reissek (Celastraceae) chichuá Amazon

(2016) Dionatas Ulises de Oliveira Meneguetti et al.   Revista da Sociedade Brasileira de Medicina Tropical

Total Synthesis of Celastrol, Development of a Platform to Access Celastroid Natural Products

(2015) Andrew M. Camelio et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Organic chemistry: Natural polarity inverted

(2015) Fedor Romanov-Michailidis et al.   NATURE

Trypanocidal Activity of Quinonemethide Triterpenoids from Cheiloclinium cognatum (Hippocrateaceae)

(2015) Luciano M. Liaõ et al.   ZEITSCHRIFT FUR NATURFORSCHUNG SECTION C-A JOURNAL OF BIOSCIENCES

Antiprotozoal Activity of Quinonemethide Triterpenes from Maytenus ilicifolia (Celastraceae)

(2013) Vania dos Santos et al.   MOLECULES

A Parasite Rescue and Transformation Assay for Antileishmanial Screening Against Intracellular Leishmania donovani Amastigotes in THP1 Human Acute Monocytic Leukemia Cell Line

(2012) Surendra K. Jain et al.   Jove-Journal of Visualized Experiments

Therapeutic Potential of a Combination of Two Gene-Specific Small Interfering RNAs against Clinical Strains of Acanthamoeba

(2010) J. Lorenzo-Morales et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Neglected tropical diseases

(2010) N. Feasey et al.   BRITISH MEDICAL BULLETIN

Phytochemical and biological investigations of Elaeodendron schlechteranum

(2010) Sheila M. Maregesi et al.   JOURNAL OF ETHNOPHARMACOLOGY

The Relationship between Leishmaniasis and AIDS: the Second 10 Years

(2008) J. Alvar et al.   CLINICAL MICROBIOLOGY REVIEWS