Assessing the effectiveness of AS-48 in experimental mice models of Chagas’ disease

Insights into Chagas treatment based on the potential of bacteriocin AS-48

(2019) Rubén Martín-Escolano et al.   International Journal for Parasitology-Drugs and Drug Resistance

Preclinical studies of toxicity and safety of the AS-48 bacteriocin

(2019) Rubén Cebrián et al.   Journal of Advanced Research

Synergy between circular bacteriocin AS-48 and ethambutol against Mycobacterium tuberculosis

(2018) Clara Aguilar-Pérez et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Therapeutic peptides: Historical perspectives, current development trends, and future directions

(2018) Jolene L. Lau et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Second Generation of Mannich Base-Type Derivatives with in Vivo Activity against Trypanosoma cruzi

(2018) Rubén Martín-Escolano et al.   JOURNAL OF MEDICINAL CHEMISTRY

Autophagic-related cell death of Trypanosoma brucei induced by bacteriocin AS-48

(2018) Marta Martínez-García et al.   International Journal for Parasitology-Drugs and Drug Resistance

Polymerase Chain Reaction Detection of Trypanosoma cruzi in Macaca fascicularis Using Archived Tissues

(2018) Jeff T. Williams et al.   AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE

Control of Propionibacterium acnes by natural antimicrobial substances: Role of the bacteriocin AS-48 and lysozyme

(2018) Rubén Cebrián et al.   Scientific Reports

The therapeutic applications of antimicrobial peptides (AMPs): a patent review

(2016) Hee-Kyoung Kang et al.   JOURNAL OF MICROBIOLOGY

Status of vaccine research and development of vaccines for Chagas disease

(2016) Coreen M. Beaumier et al.   VACCINE

Nitroheterocyclic drugs cure experimental Trypanosoma cruzi infections more effectively in the chronic stage than in the acute stage

(2016) Amanda Fortes Francisco et al.   Scientific Reports

Synthesis and evaluation of in vitro and in vivo trypanocidal properties of a new imidazole-containing nitrophthalazine derivative

(2015) Francisco Olmo et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

The bacteriocin AS-48 requires dimer dissociation followed by hydrophobic interactions with the membrane for antibacterial activity

(2015) Rubén Cebrián et al.   JOURNAL OF STRUCTURAL BIOLOGY

Chagas’ Disease

(2015) Caryn Bern   NEW ENGLAND JOURNAL OF MEDICINE

Bioluminescence imaging of chronicTrypanosoma cruziinfections reveals tissue-specific parasite dynamics and heart disease in the absence of locally persistent infection

(2014) Michael D. Lewis et al.   CELLULAR MICROBIOLOGY

Synthesis and Biological Evaluation of N,N′-Squaramides with High in Vivo Efficacy and Low Toxicity: Toward a Low-Cost Drug against Chagas Disease

(2014) Francisco Olmo et al.   JOURNAL OF MEDICINAL CHEMISTRY

Drug discovery for Chagas disease should consider Trypanosoma cruzi strain diversity

(2014) Bianca Zingales et al.   MEMORIAS DO INSTITUTO OSWALDO CRUZ

Screening strategies to identify new chemical diversity for drug development to treat kinetoplastid infections

(2013) ROB DON et al.   PARASITOLOGY

Melittin peptide kills Trypanosoma cruzi parasites by inducing different cell death pathways

(2013) Camila M. Adade et al.   TOXICON

Oral Transmission of Chagas Disease

(2012) M. A. Shikanai-Yasuda et al.   CLINICAL INFECTIOUS DISEASES

Antimicrobial Peptides for Therapeutic Applications: A Review

(2012) Min-Duk Seo et al.   MOLECULES

Molecular Characterization of Antimicrobial Peptide Genes of the Carpenter Ant Camponotus floridanus

(2012) Carolin Ratzka et al.   PLoS One

Role of lipids in the interaction of antimicrobial peptides with membranes

(2012) Vitor Teixeira et al.   PROGRESS IN LIPID RESEARCH

Trypanosoma cruzi: Seroprevalence Detection in Suburban Population of Santiago de Querétaro (Mexico)

(2012) Ángeles López-Céspedes et al.   TheScientificWorldJOURNAL

Are Bacteriocins Underexploited? NOVEL Applications for OLD Antimicrobials

(2011) Manuel Montalban-Lopez et al.   CURRENT PHARMACEUTICAL BIOTECHNOLOGY

Characterization of functional, safety, and probiotic properties of Enterococcus faecalis UGRA10, a new AS-48-producer strain

(2011) R. Cebrián et al.   FOOD MICROBIOLOGY

Advances and challenges towards a vaccine against Chagas disease

(2011) Israel Quijano-Hernandez et al.   Human vaccines & immunotherapeutics

Integrated Dataset of Screening Hits against Multiple Neglected Disease Pathogens

(2011) Solomon Nwaka et al.   PLoS Neglected Tropical Diseases

Activity In Vivo of Anti-Trypanosoma cruzi Compounds Selected from a High Throughput Screening

(2011) Grasiella Andriani et al.   PLoS Neglected Tropical Diseases

The innate immune response to Trypanosoma cruzi infection

(2010) Hisako Kayama et al.   MICROBES AND INFECTION

Benznidazole alters the pattern of Cyclophosphamide-induced reactivation in experimental Trypanosoma cruzi-dependent lineage infection

(2009) Daniela M. Santos et al.   ACTA TROPICA

Encapsulation for preservation of functionality and targeted delivery of bioactive food components

(2009) Paul de Vos et al.   INTERNATIONAL DAIRY JOURNAL

Current epidemiological trends for Chagas disease in Latin America and future challenges in epidemiology, surveillance and health policy

(2009) Álvaro Moncayo et al.   MEMORIAS DO INSTITUTO OSWALDO CRUZ

Optimization of enterocin AS-48 production on a whey-based substrate

(2008) S. Ananou et al.   INTERNATIONAL DAIRY JOURNAL

Divergent roles of endothelial NF-κB in multiple organ injury and bacterial clearance in mouse models of sepsis

(2008) Xiaobing Ye et al.   JOURNAL OF EXPERIMENTAL MEDICINE

A mechanism for cross-resistance to nifurtimox and benznidazole in trypanosomes

(2008) Shane R. Wilkinson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA