Roles of diet-associated gut microbial metabolites on brain health: cell-to-cell interactions between gut bacteria and the central nervous system

Gut microbiota indole-3-propionic acid mediates neuroprotective effect of probiotic consumption in healthy elderly: A randomized, double-blind, placebo-controlled, multicenter trial and in vitro study

(2023) Chong-Su Kim et al.   CLINICAL NUTRITION

A systematic review of gut microbiota composition in observational studies of major depressive disorder, bipolar disorder and schizophrenia

(2022) A. J. McGuinness et al.   MOLECULAR PSYCHIATRY

Short chain fatty acids: Microbial metabolites for gut-brain axis signalling

(2022) Kenneth J. O'Riordan et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Microbiota–brain axis: Context and causality

(2022) John F. Cryan et al.   SCIENCE

Role of diet and its effects on the gut microbiome in the pathophysiology of mental disorders

(2022) J. Horn et al.   Translational Psychiatry

Overlapping Mechanisms of Action of Brain-Active Bacteria and Bacterial Metabolites in the Pathogenesis of Common Brain Diseases

(2022) Tanja Patricia Eicher et al.   Nutrients

Perspective: Leveraging the Gut Microbiota to Predict Personalized Responses to Dietary, Prebiotic, and Probiotic Interventions

(2022) Sean M Gibbons et al.   Advances in Nutrition

Experiencing social exclusion changes gut microbiota composition

(2022) Chong-Su Kim et al.   Translational Psychiatry

Microbiota-derived metabolites as drivers of gut–brain communication

(2022) Hany Ahmed et al.   Gut Microbes

The Role of a Gut Microbial-Derived Metabolite, Trimethylamine N-Oxide (TMAO), in Neurological Disorders

(2022) Sankar Simla Praveenraj et al.   MOLECULAR NEUROBIOLOGY

Short-Chain Fatty Acids Reduce Oligodendrocyte Precursor Cells Loss by Inhibiting the Activation of Astrocytes via the SGK1/IL-6 Signalling Pathway

(2022) Yanmin Gao et al.   NEUROCHEMICAL RESEARCH

Regulation of microglial physiology by the microbiota

(2022) James Cook et al.   Gut Microbes

Gut microbiota-derived metabolites and their importance in neurological disorders

(2022) Nicole Mary Swer et al.   MOLECULAR BIOLOGY REPORTS

The aryl hydrocarbon receptor and the gut–brain axis

(2021) Andreia Barroso et al.   Cellular & Molecular Immunology

Microbiome connections with host metabolism and habitual diet from 1,098 deeply phenotyped individuals

(2021) Francesco Asnicar et al.   NATURE MEDICINE

Microbial Regulation of Host Physiology by Short-chain Fatty Acids

(2021) Bart van der Hee et al.   TRENDS IN MICROBIOLOGY

Genome-Scale Metabolic Modeling of the Human Microbiome in the Era of Personalized Medicine

(2021) Almut Heinken et al.   Annual Review of Microbiology

Gut microbes impact stroke severity via the trimethylamine N-oxide pathway

(2021) Weifei Zhu et al.   Cell Host & Microbe

Tryptophan-metabolizing gut microbes regulate adult neurogenesis via the aryl hydrocarbon receptor

(2021) George Zhang Wei et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The human gut microbiome and health inequities

(2021) Katherine R. Amato et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Gut–Brain Axis

(2021) Emeran A. Mayer et al.   Annual Review of Medicine

Regulation of common neurological disorders by gut microbial metabolites

(2021) Jeongho Park et al.   EXPERIMENTAL AND MOLECULAR MEDICINE

Temporal variability in quantitative human gut microbiome profiles and implications for clinical research

(2021) Doris Vandeputte et al.   Nature Communications

Bile acid metabolism is altered in multiple sclerosis and supplementation ameliorates neuroinflammation

(2020) Pavan Bhargava et al.   JOURNAL OF CLINICAL INVESTIGATION

Probiotic Supplementation Improves Cognitive Function and Mood with Changes in Gut Microbiota in Community-Dwelling Older Adults: A Randomized, Double-Blind, Placebo-Controlled, Multicenter Trial

(2020) Chong-Su Kim et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Multidisciplinary intervention in the treatment of mixed anxiety and depression disorder

(2020) Vicente Javier Clemente-Suárez   PHYSIOLOGY & BEHAVIOR

Gut microbiota in human metabolic health and disease

(2020) Yong Fan et al.   NATURE REVIEWS MICROBIOLOGY

The gut microbiota–brain axis in behaviour and brain disorders

(2020) Livia H. Morais et al.   NATURE REVIEWS MICROBIOLOGY

Gut microbial molecules in behavioural and neurodegenerative conditions

(2020) Brittany D. Needham et al.   NATURE REVIEWS NEUROSCIENCE

Bile Acids: A Communication Channel in the Gut-Brain Axis

(2020) Vera F. Monteiro-Cardoso et al.   NEUROMOLECULAR MEDICINE

The gut microbiome–derived metabolite trimethylamine N-oxide modulates neuroinflammation and cognitive function with aging

(2020) Vienna E. Brunt et al.   GeroScience

Gut microbiota composition is associated with newborn functional brain connectivity and behavioral temperament

(2020) Caroline M. Kelsey et al.   BRAIN BEHAVIOR AND IMMUNITY

Intestinal Bacteria Interplay With Bile and Cholesterol Metabolism: Implications on Host Physiology

(2019) Natalia Molinero et al.   Frontiers in Physiology

A new genomic blueprint of the human gut microbiota

(2019) Alexandre Almeida et al.   NATURE

Gut microbiota composition is associated with temperament traits in infants

(2019) Anna-Katariina Aatsinki et al.   BRAIN BEHAVIOR AND IMMUNITY

The role of short-chain fatty acids in microbiota–gut–brain communication

(2019) Boushra Dalile et al.   Nature Reviews Gastroenterology & Hepatology

Daily Sampling Reveals Personalized Diet-Microbiome Associations in Humans

(2019) Abigail J. Johnson et al.   Cell Host & Microbe

Gut feelings: A randomised, triple-blind, placebo-controlled trial of probiotics for depressive symptoms

(2019) Bahia Chahwan et al.   JOURNAL OF AFFECTIVE DISORDERS

Leveraging non-human primates for exploring the social transmission of microbes

(2019) Sahana Kuthyar et al.   CURRENT OPINION IN MICROBIOLOGY

Diet–microbiota interactions and personalized nutrition

(2019) Aleksandra A. Kolodziejczyk et al.   NATURE REVIEWS MICROBIOLOGY

Butyrate suppresses demyelination and enhances remyelination

(2019) Tong Chen et al.   Journal of Neuroinflammation

Diversification of host bile acids by members of the gut microbiota

(2019) Jenessa A. Winston et al.   Gut Microbes

The Gut Microbiome as a Therapeutic Target for Cognitive Impairment

(2019) Yi Sun et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Tryptophan Metabolism: A Link Between the Gut Microbiota and Brain

(2019) Kan Gao et al.   Advances in Nutrition

The Impact of Dietary Fiber on Gut Microbiota in Host Health and Disease

(2018) Kassem Makki et al.   Cell Host & Microbe

Human gut microbiome: hopes, threats and promises

(2018) Patrice D Cani   GUT

Microglial control of astrocytes in response to microbial metabolites

(2018) Veit Rothhammer et al.   NATURE

The Microbiome in Psychology and Cognitive Neuroscience

(2018) Amar Sarkar et al.   TRENDS IN COGNITIVE SCIENCES

Sodium Butyrate Improves Memory Function in an Alzheimer's Disease Mouse Model When Administered at an Advanced Stage of Disease Progression

(2018) Nambirajan Govindarajan et al.   JOURNAL OF ALZHEIMERS DISEASE

You are what you eat: diet, health and the gut microbiota

(2018) Niv Zmora et al.   Nature Reviews Gastroenterology & Hepatology

The Gut–Brain Axis and the Microbiome: Mechanisms and Clinical Implications

(2018) Vadim Osadchiy et al.   Clinical Gastroenterology and Hepatology

Microbiome–microglia connections via the gut–brain axis

(2018) Reem Abdel-Haq et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Glia as architects of central nervous system formation and function

(2018) Nicola J. Allen et al.   SCIENCE

Gut microbiota functions: metabolism of nutrients and other food components

(2017) Ian Rowland et al.   EUROPEAN JOURNAL OF NUTRITION

Microbial metabolites in health and disease: Navigating the unknown in search of function

(2017) Kristina B. Martinez et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

TUDCA: An Agonist of the Bile Acid Receptor GPBAR1/TGR5 With Anti-Inflammatory Effects in Microglial Cells

(2017) Natalia Yanguas-Casás et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Neurotoxic reactive astrocytes are induced by activated microglia

(2017) Shane A. Liddelow et al.   NATURE

Adult hippocampal neurogenesis and cognitive flexibility — linking memory and mood

(2017) Christoph Anacker et al.   NATURE REVIEWS NEUROSCIENCE

Brain Autoimmunity and Intestinal Microbiota: 100 Trillion Game Changers

(2017) Hartmut Wekerle   TRENDS IN IMMUNOLOGY

Gut Microbiota Regulate Motor Deficits and Neuroinflammation in a Model of Parkinson’s Disease

(2016) Timothy R. Sampson et al.   CELL

From Dietary Fiber to Host Physiology: Short-Chain Fatty Acids as Key Bacterial Metabolites

(2016) Ara Koh et al.   CELL

Mitochondrial Dynamics Impacts Stem Cell Identity and Fate Decisions by Regulating a Nuclear Transcriptional Program

(2016) Mireille Khacho et al.   Cell Stem Cell

Effects of bile acids on neurological function and disease

(2016) Matthew McMillin et al.   FASEB JOURNAL

Bile Acids Control Inflammation and Metabolic Disorder through Inhibition of NLRP3 Inflammasome

(2016) Chuansheng Guo et al.   IMMUNITY

TGFβ Contributes to the Anti-inflammatory Effects of Tauroursodeoxycholic Acid on an Animal Model of Acute Neuroinflammation

(2016) Natalia Yanguas-Casás et al.   MOLECULAR NEUROBIOLOGY

Type I interferons and microbial metabolites of tryptophan modulate astrocyte activity and central nervous system inflammation via the aryl hydrocarbon receptor

(2016) Veit Rothhammer et al.   NATURE MEDICINE

Signals from the gut microbiota to distant organs in physiology and disease

(2016) Bjoern O Schroeder et al.   NATURE MEDICINE

Sodium butyrate attenuates social behavior deficits and modifies the transcription of inhibitory/excitatory genes in the frontal cortex of an autism model

(2016) Neta Kratsman et al.   NEUROPHARMACOLOGY

Astrocytes: Key Regulators of Neuroinflammation

(2016) Emanuela Colombo et al.   TRENDS IN IMMUNOLOGY

Microbial metabolism of dietary components to bioactive metabolites: opportunities for new therapeutic interventions

(2016) Linda S. Zhang et al.   Genome Medicine

Microbiota-driven transcriptional changes in prefrontal cortex override genetic differences in social behavior

(2016) Mar Gacias et al.   eLife

Interaction of dietary compounds, especially polyphenols, with the intestinal microbiota: a review

(2015) Aleksandra Duda-Chodak et al.   EUROPEAN JOURNAL OF NUTRITION

Systemic inflammation and microglial activation: systematic review of animal experiments

(2015) Inge C.M. Hoogland et al.   Journal of Neuroinflammation

Host microbiota constantly control maturation and function of microglia in the CNS

(2015) Daniel Erny et al.   NATURE NEUROSCIENCE

Microglia: Dynamic Mediators of Synapse Development and Plasticity

(2015) Yuwen Wu et al.   TRENDS IN IMMUNOLOGY

Serotonin stimulates secretion of exosomes from microglia cells

(2014) Konstantin Glebov et al.   GLIA

Microglia as modulators of cognition and neuropsychiatric disorders

(2012) Thomas Blank et al.   GLIA

Astrocytes and human cognition: Modeling information integration and modulation of neuronal activity

(2010) Alfredo Pereira et al.   PROGRESS IN NEUROBIOLOGY

Inhibition of ERK1/2 prevents neural and mesendodermal differentiation and promotes human embryonic stem cell self-renewal

(2010) Jie Na et al.   Stem Cell Research

Mechanisms and Functional Implications of Adult Neurogenesis

(2008) Chunmei Zhao et al.   CELL