Scribble, Lgl1, and myosin IIA interact with α-/β-catenin to maintain epithelial junction integrity

Scribble, Lgl1, and myosin II form a complex in vivo to promote directed cell migration

(2020) Maha Abedrabbo et al.   MOLECULAR BIOLOGY OF THE CELL

Adherens junction regulates cryptic lamellipodia formation for epithelial cell migration

(2020) Masayuki Ozawa et al.   JOURNAL OF CELL BIOLOGY

The Scribble family in cancer: twentieth anniversary

(2020) Marie-Josée Santoni et al.   ONCOGENE

Scribble: A master scaffold in polarity, adhesion, synaptogenesis, and proliferation

(2019) Teresa T. Bonello et al.   JOURNAL OF CELL BIOLOGY

NMIIA promotes tumor growth and metastasis by activating the Wnt/β-catenin signaling pathway and EMT in pancreatic cancer

(2019) Pingting Zhou et al.   ONCOGENE

The E-Cadherin and N-Cadherin Switch in Epithelial-to-Mesenchymal Transition: Signaling, Therapeutic Implications, and Challenges

(2019) Loh et al.   Cells

New insights into apical-basal polarization in epithelia

(2019) Amalia Riga et al.   CURRENT OPINION IN CELL BIOLOGY

The Scribble Cell Polarity Module in the Regulation of Cell Signaling in Tissue Development and Tumorigenesis

(2018) Rebecca Stephens et al.   JOURNAL OF MOLECULAR BIOLOGY

Nonmuscle myosin IIA is involved in recruitment of apical junction components through activation of α-catenin

(2018) Masayuki Ozawa   Biology Open

E-cadherin bridges cell polarity and spindle orientation to ensure prostate epithelial integrity and prevent carcinogenesis in vivo

(2018) Xue Wang et al.   PLoS Genetics

Integration of Cadherin Adhesion and Cytoskeleton at Adherens Junctions

(2017) René Marc Mège et al.   Cold Spring Harbor Perspectives in Biology

Contractile forces at tricellular contacts modulate epithelial organization and monolayer integrity

(2017) Julie Salomon et al.   Nature Communications

Mechanics of epithelial tissues during gap closure

(2016) Simon Begnaud et al.   CURRENT OPINION IN CELL BIOLOGY

Myosin-dependent remodeling of adherens junctions protects junctions from Snail-dependent disassembly

(2016) Mo Weng et al.   JOURNAL OF CELL BIOLOGY

Highly efficient Cas9-mediated transcriptional programming

(2015) Alejandro Chavez et al.   NATURE METHODS

Scribble acts as an oncogene in Eμ-myc-driven lymphoma

(2015) E D Hawkins et al.   ONCOGENE

Actomyosin networks and tissue morphogenesis

(2014) Akankshi Munjal et al.   DEVELOPMENT

Molecular mechanisms of epithelial–mesenchymal transition

(2014) Samy Lamouille et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Organization and execution of the epithelial polarity programme

(2014) Enrique Rodriguez-Boulan et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Large-scale interaction profiling of PDZ domains through proteomic peptide-phage display using human and viral phage peptidomes

(2014) Y. Ivarsson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Family-wide Investigation of PDZ Domain-Mediated Protein-Protein Interactions Implicates β-Catenin in Maintaining the Integrity of Tight Junctions

(2013) Taranjit S. Gujral et al.   CHEMISTRY & BIOLOGY

The Par3/Par6/aPKC complex and epithelial cell polarity

(2013) Jia Chen et al.   EXPERIMENTAL CELL RESEARCH

Scribble regulates an EMT polarity pathway through modulation of MAPK-ERK signaling to mediate junction formation

(2013) I. A. Elsum et al.   JOURNAL OF CELL SCIENCE

The tumor suppressor Lgl1 forms discrete complexes with NMII-A and Par6 -aPKC  that are affected by Lgl1 phosphorylation

(2013) I. Dahan et al.   JOURNAL OF CELL SCIENCE

Scrib heterozygosity predisposes to lung cancer and cooperates with KRas hyperactivation to accelerate lung cancer progression in vivo

(2013) I A Elsum et al.   ONCOGENE

Nonmuscle myosin-2: mix and match

(2012) Sarah M. Heissler et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

The Scribble–Dlg–Lgl polarity module in development and cancer: from flies to man

(2012) Imogen Elsum et al.   Essays in Biochemistry

The tumor suppressor Lgl1 regulates NMII-A cellular distribution and focal adhesion morphology to optimize cell migration

(2012) Inbal Dahan et al.   MOLECULAR BIOLOGY OF THE CELL

The human Lgl polarity gene, Hugl-2, induces MET and suppresses Snail tumorigenesis

(2012) A Kashyap et al.   ONCOGENE

The Scribble Polarity Protein Stabilizes E-Cadherin/p120-Catenin Binding and Blocks Retrieval of E-Cadherin to the Golgi

(2012) Madhura Lohia et al.   PLoS One

The regulation of cell-cell adhesion during epithelial-mesenchymal transition, motility and tumor progression

(2012) Grégoire F. Le Bras et al.   Cell Adhesion & Migration

Aberrant Overexpression of the Cell Polarity Module Scribble in Human Cancer

(2011) Valentina Vaira et al.   AMERICAN JOURNAL OF PATHOLOGY

The Hippo Transducer TAZ Confers Cancer Stem Cell-Related Traits on Breast Cancer Cells

(2011) Michelangelo Cordenonsi et al.   CELL

Paracrine and Autocrine Signals Induce and Maintain Mesenchymal and Stem Cell States in the Breast

(2011) Christina Scheel et al.   CELL

SCRIB expression is deregulated in human prostate cancer, and its deficiency in mice promotes prostate neoplasia

(2011) Helen B. Pearson et al.   JOURNAL OF CLINICAL INVESTIGATION

Dynamic actin remodeling during epithelial–mesenchymal transition depends on increased moesin expression

(2011) Jennifer Haynes et al.   MOLECULAR BIOLOGY OF THE CELL

A protein complex of SCRIB, NOS1AP and VANGL1 regulates cell polarity and migration and is associated with breast cancer progression

(2011) J N Anastas et al.   ONCOGENE

Multicomponent Analysis of Junctional Movements Regulated by Myosin II Isoforms at the Epithelial Zonula Adherens

(2011) Michael Smutny et al.   PLoS One

The phosphorylation state of MRLC is polyamine dependent in intestinal epithelial cells

(2010) Mitulkumar N. Bavaria et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Polarity protein alterations in carcinoma: a focus on emerging roles for polarity regulators

(2010) Ling Huang et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Phosphorylation state regulates the localization of Scribble at adherens junctions and its association with E-cadherin–catenin complexes

(2010) Ken Yoshihara et al.   EXPERIMENTAL CELL RESEARCH

Myosin II isoforms identify distinct functional modules that support integrity of the epithelial zonula adherens

(2010) Michael Smutny et al.   NATURE CELL BIOLOGY

Core epithelial-to-mesenchymal transition interactome gene-expression signature is associated with claudin-low and metaplastic breast cancer subtypes

(2010) J. H. Taube et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mechanical tugging force regulates the size of cell-cell junctions

(2010) Z. Liu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

TGF-β-induced epithelial to mesenchymal transition

(2009) Jian Xu et al.   CELL RESEARCH

Epithelial Polarity: Interactions Between Junctions and Apical-Basal Machinery

(2009) N. A. Kaplan et al.   GENETICS

Scribble Interacts with β-Catenin to Localize Synaptic Vesicles to Synapses

(2009) Yu Sun et al.   MOLECULAR BIOLOGY OF THE CELL

Enzymatic assembly of DNA molecules up to several hundred kilobases

(2009) Daniel G Gibson et al.   NATURE METHODS

Non-muscle myosin II takes centre stage in cell adhesion and migration

(2009) Miguel Vicente-Manzanares et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The Transcriptional Repressor ZEB1 Promotes Metastasis and Loss of Cell Polarity in Cancer

(2008) S. Spaderna et al.   CANCER RESEARCH

Deregulation of Scribble Promotes Mammary Tumorigenesis and Reveals a Role for Cell Polarity in Carcinoma

(2008) Lixing Zhan et al.   CELL

The transcription factor snail represses Crumbs3 expression and disrupts apico-basal polarity complexes

(2008) E L Whiteman et al.   ONCOGENE

Transcriptional regulation of cell polarity in EMT and cancer

(2008) G Moreno-Bueno et al.   ONCOGENE

Adherens and tight junctions: Structure, function and connections to the actin cytoskeleton

(2007) Andrea Hartsock et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES