Scribble acts as an oncogene in Eμ-myc-driven lymphoma

Mislocalization of the Cell Polarity Protein Scribble Promotes Mammary Tumorigenesis and Is Associated with Basal Breast Cancer

(2014) M. E. Feigin et al.   CANCER RESEARCH

Lethal Giant Larvae 1 Tumour Suppressor Activity Is Not Conserved in Models of Mammalian T and B Cell Leukaemia

(2014) Edwin D. Hawkins et al.   PLoS One

Scribble Modulates the MAPK/Fra1 Pathway to Disrupt Luminal and Ductal Integrity and Suppress Tumour Formation in the Mammary Gland

(2014) Nathan J. Godde et al.   PLoS Genetics

Scribble regulates an EMT polarity pathway through modulation of MAPK-ERK signaling to mediate junction formation

(2013) I. A. Elsum et al.   JOURNAL OF CELL SCIENCE

An MRAS, SHOC2, and SCRIB Complex Coordinates ERK Pathway Activation with Polarity and Tumorigenic Growth

(2013) Lucy C. Young et al.   MOLECULAR CELL

Regulation of asymmetric cell division and polarity by Scribble is not required for humoral immunity

(2013) Edwin D. Hawkins et al.   Nature Communications

Novel Mechanism of Tumor Suppression by Polarity Gene Discs Large 1 (DLG1) Revealed in a Murine Model of Pediatric B-ALL

(2013) G. J. Sandoval et al.   Cancer Immunology Research

Tumor Type-Dependent Function of the Par3 Polarity Protein in Skin Tumorigenesis

(2012) Sandra Iden et al.   CANCER CELL

Suppression of Ras/Mapk pathway signaling inhibits Myc-induced lymphomagenesis

(2012) M W Gramling et al.   CELL DEATH AND DIFFERENTIATION

Characterization of In Vivo Dlg1 Deletion on T Cell Development and Function

(2012) Lisa A. Humphries et al.   PLoS One

Cell polarity proteins and cancer

(2012) Saskia I.J. Ellenbroek et al.   SEMINARS IN CANCER BIOLOGY

Asymmetric segregation and self-renewal of hematopoietic stem and progenitor cells with endocytic Ap2a2

(2011) S. B. Ting et al.   BLOOD

SCRIB expression is deregulated in human prostate cancer, and its deficiency in mice promotes prostate neoplasia

(2011) Helen B. Pearson et al.   JOURNAL OF CLINICAL INVESTIGATION

A protein complex of SCRIB, NOS1AP and VANGL1 regulates cell polarity and migration and is associated with breast cancer progression

(2011) J N Anastas et al.   ONCOGENE

miR-296 regulation of a cell polarity–cell plasticity module controls tumor progression

(2011) V Vaira et al.   ONCOGENE

Asymmetric Cell Division of T Cells upon Antigen Presentation Uses Multiple Conserved Mechanisms

(2010) J. Oliaro et al.   JOURNAL OF IMMUNOLOGY

The cell polarity regulator hScrib controls ERK activation through a KIM site-dependent interaction

(2010) K Nagasaka et al.   ONCOGENE

Immature T-cell clustering and efficient differentiation require the polarity protein Scribble

(2010) K. A. Pike et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Concise Review: Polarity in Stem Cells, Disease, and Aging

(2010) Maria Carolina Florian et al.   STEM CELLS

Defective expression of polarity protein PAR-3 gene (PARD3) in esophageal squamous cell carcinoma

(2009) K Zen et al.   ONCOGENE

Lessons from development: A role for asymmetric stem cell division in cancer

(2009) Anne E. Powell et al.   Stem Cell Research

Linking Cell Cycle to Asymmetric Division: Aurora-A Phosphorylates the Par Complex to Regulate Numb Localization

(2008) Frederik Wirtz-Peitz et al.   CELL

Deregulation of Scribble Promotes Mammary Tumorigenesis and Reveals a Role for Cell Polarity in Carcinoma

(2008) Lixing Zhan et al.   CELL

Upsides and downsides to polarity and asymmetric cell division in leukemia

(2008) E D Hawkins et al.   ONCOGENE

Loss of human Scribble cooperates with H-Ras to promote cell invasion through deregulation of MAPK signalling

(2008) L E Dow et al.   ONCOGENE