The regulation of cell-cell adhesion during epithelial-mesenchymal transition, motility and tumor progression

Epithelial–mesenchymal transition and cancer stemness: the Twist1–Bmi1 connection

(2013) Kou‑Juey Wu et al.   BIOSCIENCE REPORTS

Cadherin switch from E- to N-cadherin in melanoma progression is regulated by the PI3K/PTEN pathway through Twist and Snail

(2012) L. Hao et al.   BRITISH JOURNAL OF DERMATOLOGY

How reggies regulate regeneration and axon growth

(2012) Claudia A. O. Stuermer   CELL AND TISSUE RESEARCH

Structure of a novel phosphotyrosine-binding domain in Hakai that targets E-cadherin

(2012) Manjeet Mukherjee et al.   EMBO JOURNAL

A complex Polycomb issue: the two faces of EZH2 in cancer

(2012) H. Hock   GENES & DEVELOPMENT

N-cadherin-mediated cell-cell adhesion promotes cell migration in a three-dimensional matrix

(2012) W. Shih et al.   JOURNAL OF CELL SCIENCE

G9a interacts with Snail and is critical for Snail-mediated E-cadherin repression in human breast cancer

(2012) Chenfang Dong et al.   JOURNAL OF CLINICAL INVESTIGATION

Matrix rigidity regulates a switch between TGF-β1–induced apoptosis and epithelial–mesenchymal transition

(2012) Jennifer L. Leight et al.   MOLECULAR BIOLOGY OF THE CELL

Reggies/flotillins regulate E-cadherin–mediated cell contact formation by affecting EGFR trafficking

(2012) Gonzalo P. Solis et al.   MOLECULAR BIOLOGY OF THE CELL

Interaction with Suv39H1 is critical for Snail-mediated E-cadherin repression in breast cancer

(2012) C Dong et al.   ONCOGENE

Endocytosis and Signaling: Cell Logistics Shape the Eukaryotic Cell Plan

(2012) Sara Sigismund et al.   PHYSIOLOGICAL REVIEWS

The Ins and Outs of the Epithelial to Mesenchymal Transition in Health and Disease

(2011) M. Angela Nieto   Annual Review of Cell and Developmental Biology

Endocytosis and signaling

(2011) Harald W Platta et al.   CURRENT OPINION IN CELL BIOLOGY

Identification of PTPN23 as a novel regulator of cell invasion in mammary epithelial cells from a loss-of-function screen of the 'PTP-ome'

(2011) G. Lin et al.   GENES & DEVELOPMENT

Epithelial Protein Lost In Neoplasm (EPLIN) Interacts with α-Catenin and Actin Filaments in Endothelial Cells and Stabilizes Vascular Capillary Networkin Vitro

(2011) Adeline Chervin-Pétinot et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mechanosensitive EPLIN-dependent remodeling of adherens junctions regulates epithelial reshaping

(2011) Katsutoshi Taguchi et al.   JOURNAL OF CELL BIOLOGY

Matrix stiffening sensitizes epithelial cells to EGF and enables the loss of contact inhibition of proliferation

(2011) J.-H. Kim et al.   JOURNAL OF CELL SCIENCE

The roles of flotillin microdomains - endocytosis and beyond

(2011) G. P. Otto et al.   JOURNAL OF CELL SCIENCE

Caveolin-1 overexpression is associated with simultaneous abnormal expression of the E-cadherin/α-β catenins complex and multiple erbb receptors and with lymph nodes metastasis in head and neck squamous cell carcinomas

(2011) Laura Masuelli et al.   JOURNAL OF CELLULAR PHYSIOLOGY

SIRT1 Deacetylates the DNA Methyltransferase 1 (DNMT1) Protein and Alters Its Activities

(2011) L. Peng et al.   MOLECULAR AND CELLULAR BIOLOGY

Numb controls E-cadherin endocytosis through p120 catenin with aPKC

(2011) Kazuhide Sato et al.   MOLECULAR BIOLOGY OF THE CELL

Bmi-1 promotes invasion and metastasis, and its elevated expression is correlated with an advanced stage of breast cancer

(2011) Bao-Hong Guo et al.   Molecular Cancer

Identification of an mRNP Complex Regulating Tumorigenesis at the Translational Elongation Step

(2011) George S. Hussey et al.   MOLECULAR CELL

Regulation of SNAIL1 and E-cadherin function by DNMT1 in a DNA methylation-independent context

(2011) Jesús Espada et al.   NUCLEIC ACIDS RESEARCH

Akt2 interacts with Snail1 in the E-cadherin promoter

(2011) P Villagrasa et al.   ONCOGENE

Regulation of ovarian cancer progression by microRNA-187 through targeting Disabled homolog-2

(2011) A Chao et al.   ONCOGENE

Rapid Suppression of Activated Rac1 by Cadherins and Nectins during De Novo Cell-Cell Adhesion

(2011) Khameeka N. Kitt et al.   PLoS One

TGF-β Regulates DNA Methyltransferase Expression in Prostate Cancer, Correlates with Aggressive Capabilities, and Predicts Disease Recurrence

(2011) Qiang Zhang et al.   PLoS One

Roles of the Polycomb group proteins in stem cells and cancer

(2011) H Richly et al.   Cell Death & Disease

Strength Dependence of Cadherin-Mediated Adhesions

(2010) Benoit Ladoux et al.   BIOPHYSICAL JOURNAL

Disabled-2 downregulation promotes epithelial-to-mesenchymal transition

(2010) J C Martin et al.   BRITISH JOURNAL OF CANCER

Smad Signaling Is Required to Maintain Epigenetic Silencing during Breast Cancer Progression

(2010) P. Papageorgis et al.   CANCER RESEARCH

Src-mediated regulation of homotypic cell adhesion: implications for cancer progression and opportunities for therapeutic intervention

(2010) Anshu Wadhawan et al.   CANCER TREATMENT REVIEWS

Modulation of E-cadherin expression by K-Ras; involvement of DNA methyltransferase-3b

(2010) Osong Kwon et al.   CARCINOGENESIS

EZH2 supports ovarian carcinoma cell invasion and/or metastasis via regulation of TGF-β1 and is a predictor of outcome in ovarian carcinoma patients

(2010) Zhi-Yue Rao et al.   CARCINOGENESIS

Dynamic and Static Interactions between p120 Catenin and E-Cadherin Regulate the Stability of Cell-Cell Adhesion

(2010) Noboru Ishiyama et al.   CELL

The TWIST/Mi2/NuRD protein complex and its essential role in cancer metastasis

(2010) Junjiang Fu et al.   CELL RESEARCH

Collective Chemotaxis Requires Contact-Dependent Cell Polarity

(2010) Eric Theveneau et al.   DEVELOPMENTAL CELL

Methyl-H3K9-binding protein MPP8 mediates E-cadherin gene silencing and promotes tumour cell motility and invasion

(2010) Kenji Kokura et al.   EMBO JOURNAL

Numb is a negative regulator of HGF dependent cell scattering and Rac1 activation

(2010) Kimberly M. Lau et al.   EXPERIMENTAL CELL RESEARCH

Rac1 Recruits the Adapter Protein CMS/CD2AP to Cell-Cell Contacts

(2010) Trynette J. van Duijn et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Epigenetic downregulation of human disabled homolog 2 switches TGF-β from a tumor suppressor to a tumor promoter

(2010) Adèle Hannigan et al.   JOURNAL OF CLINICAL INVESTIGATION

Bmi1 is essential in Twist1-induced epithelial–mesenchymal transition

(2010) Muh-Hwa Yang et al.   NATURE CELL BIOLOGY

A distinctive role for focal adhesion proteins in three-dimensional cell motility

(2010) Stephanie I. Fraley et al.   NATURE CELL BIOLOGY

Reducing background fluorescence reveals adhesions in 3D matrices

(2010) Kristopher E. Kubow et al.   NATURE CELL BIOLOGY

Spontaneous assembly and active disassembly balance adherens junction homeostasis

(2010) Soonjin Hong et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Epithelial-Mesenchymal Transitions in Development and Disease

(2009) Jean Paul Thiery et al.   CELL

Actin Dynamics at the Leading Edge: From Simple Machinery to Complex Networks

(2009) Robert H. Insall et al.   DEVELOPMENTAL CELL

Numb regulates cell–cell adhesion and polarity in response to tyrosine kinase signalling

(2009) Zezhou Wang et al.   EMBO JOURNAL

The multiple functions of Numb

(2009) Alberto Gulino et al.   EXPERIMENTAL CELL RESEARCH

Plasticity of cell migration: a multiscale tuning model

(2009) Peter Friedl et al.   JOURNAL OF CELL BIOLOGY

The polycomb group protein Bmi-1 represses the tumor suppressor PTEN and induces epithelial-mesenchymal transition in human nasopharyngeal epithelial cells

(2009) Li-Bing Song et al.   JOURNAL OF CLINICAL INVESTIGATION

Caveolae Mediate Growth Factor-induced Disassembly of Adherens Junctions to Support Tumor Cell Dissociation

(2009) Lidiya Orlichenko et al.   MOLECULAR BIOLOGY OF THE CELL

Localized and reversible TGFβ signalling switches breast cancer cells from cohesive to single cell motility

(2009) Silvia Giampieri et al.   NATURE CELL BIOLOGY

A role for the TGF -Par6 polarity pathway in breast cancer progression

(2009) A. M. Viloria-Petit et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Regulation of Embryonic Cell Adhesion by the Prion Protein

(2009) Edward Málaga-Trillo et al.   PLOS BIOLOGY

Biochemical and structural analysis of α-catenin in cell–cell contacts

(2008) Sabine Pokutta et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Hepatitis C virus core protein downregulates E-cadherin expression via activation of DNA methyltransferase 1 and 3b

(2008) Payal Arora et al.   CANCER LETTERS

Lysyl Oxidase-Like 2 as a New Poor Prognosis Marker of Squamous Cell Carcinomas

(2008) H. Peinado et al.   CANCER RESEARCH

The Epithelial-Mesenchymal Transition Generates Cells with Properties of Stem Cells

(2008) Sendurai A. Mani et al.   CELL

The cell-cell adhesion molecule E-cadherin

(2008) F. van Roy et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Clathrin-Mediated Internalization Is Essential for Sustained EGFR Signaling but Dispensable for Degradation

(2008) Sara Sigismund et al.   DEVELOPMENTAL CELL

Reggie-1/flotillin-2 promotes secretion of the long-range signalling forms of Wingless and Hedgehog in Drosophila

(2008) Vladimir L Katanaev et al.   EMBO JOURNAL

G9a/GLP complexes independently mediate H3K9 and DNA methylation to silence transcription

(2008) Makoto Tachibana et al.   EMBO JOURNAL

Epigenetic Regulation of E-Cadherin Controls Endometrial Receptivity

(2008) Fahimeh Rahnama et al.   ENDOCRINOLOGY

Cadherin switching

(2008) M. J. Wheelock et al.   JOURNAL OF CELL SCIENCE

Polycomb Complex 2 Is Required for E-cadherin Repression by the Snail1 Transcription Factor

(2008) N. Herranz et al.   MOLECULAR AND CELLULAR BIOLOGY

Nectins and nectin-like molecules: roles in contact inhibition of cell movement and proliferation

(2008) Yoshimi Takai et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY