Infectious bronchitis virus nucleocapsid protein suppressed type I interferon production by interfering with the binding of MDA5-dsRNA and interacting with LGP2

A novel low virulent respiratory infectious bronchitis virus originating from the recombination of QX, TW and 4/91 genotype strains in China

(2020) Mengjiao Huang et al.   VETERINARY MICROBIOLOGY

Interplay between SARS-CoV-2 and the type I interferon response

(2020) Margarida Sa Ribero et al.   PLoS Pathogens

A highly pathogenic recombinant infectious bronchitis virus with adaptability in cultured cells

(2020) Mengjiao Huang et al.   VIRUS RESEARCH

Porcine deltacoronavirus nucleocapsid protein antagonizes IFN-β production by impairing dsRNA and PACT binding to RIG-I

(2019) Jun Chen et al.   VIRUS GENES

PEDV nsp16 negatively regulates innate immunity to promote viral proliferation

(2019) Peidian Shi et al.   VIRUS RESEARCH

Porcine Deltacoronavirus Nucleocapsid Protein Suppressed IFN-β Production by Interfering Porcine RIG-I dsRNA-Binding and K63-Linked Polyubiquitination

(2019) Ji Likai et al.   Frontiers in Immunology

Porcine deltacoronavirus nsp15 antagonizes interferon-β production independently of its endoribonuclease activity

(2019) Xiaorong Liu et al.   MOLECULAR IMMUNOLOGY

Swine acute diarrhea syndrome coronavirus (SADS-CoV) antagonizes interferon-β production via blocking IPS-1 and RIG-I

(2019) Zhihai Zhou et al.   VIRUS RESEARCH

Changes to taxonomy and the International Code of Virus Classification and Nomenclature ratified by the International Committee on Taxonomy of Viruses (2018)

(2018) Andrew M. Q. King et al.   ARCHIVES OF VIROLOGY

PACT Facilitates RNA-Induced Activation of MDA5 by Promoting MDA5 Oligomerization

(2017) Pak-Yin Lui et al.   JOURNAL OF IMMUNOLOGY

Inhibition of NF-κB activity by the porcine epidemic diarrhea virus nonstructural protein 1 for innate immune evasion

(2017) Qingzhan Zhang et al.   VIROLOGY

Porcine deltacoronavirus nsp5 inhibits interferon-β production through the cleavage of NEMO

(2017) Xinyu Zhu et al.   VIROLOGY

The nucleocapsid proteins of mouse hepatitis virus and severe acute respiratory syndrome coronavirus share the same IFN-β antagonizing mechanism: attenuation of PACT-mediated RIG-I/ MDA5 activation

(2017) Zhen Ding et al.   Oncotarget

Avian Interferons and Their Antiviral Effectors

(2017) Diwakar Santhakumar et al.   Frontiers in Immunology

Cellular RNA Helicase DDX1 Is Involved in Transmissible Gastroenteritis Virus nsp14-Induced Interferon-Beta Production

(2017) Yanrong Zhou et al.   Frontiers in Immunology

Dysregulated Type I Interferon and Inflammatory Monocyte-Macrophage Responses Cause Lethal Pneumonia in SARS-CoV-Infected Mice

(2016) Rudragouda Channappanavar et al.   Cell Host & Microbe

Innate immune evasion strategies of DNA and RNA viruses

(2016) Dia C Beachboard et al.   CURRENT OPINION IN MICROBIOLOGY

Infectious Bronchitis Coronavirus Limits Interferon Production by Inducing a Host Shutoff That Requires Accessory Protein 5b

(2016) Joeri Kint et al.   JOURNAL OF VIROLOGY

Structural Analysis of dsRNA Binding to Anti-viral Pattern Recognition Receptors LGP2 and MDA5

(2016) Emiko Uchikawa et al.   MOLECULAR CELL

Suppression of type I interferon production by porcine epidemic diarrhea virus and degradation of CREB-binding protein by nsp1

(2016) Qingzhan Zhang et al.   VIROLOGY

Porcine deltacoronavirus (PDCoV) infection suppresses RIG-I-mediated interferon-β production

(2016) Jingyi Luo et al.   VIROLOGY

Porcine Epidemic Diarrhea Virus 3C-Like Protease Regulates Its Interferon Antagonism by Cleaving NEMO

(2015) Dang Wang et al.   JOURNAL OF VIROLOGY

Porcine epidemic diarrhea virus inhibits dsRNA-induced interferon-β production in porcine intestinal epithelial cells by blockade of the RIG-I-mediated pathway

(2015) Liyan Cao et al.   Virology Journal

Interferon regulatory factor 7- (IRF7-) mediated immune response affects Newcastle disease virus replication in chicken embryo fibroblasts

(2014) Zhaoxiong Wang et al.   ACTA VETERINARIA HUNGARICA

MDA5 and LGP2: Accomplices and Antagonists of Antiviral Signal Transduction

(2014) K. R. Rodriguez et al.   JOURNAL OF VIROLOGY

Porcine Epidemic Diarrhea Virus Nucleocapsid Protein Antagonizes Beta Interferon Production by Sequestering the Interaction between IRF3 and TBK1

(2014) Z. Ding et al.   JOURNAL OF VIROLOGY

Activation of the Chicken Type I Interferon Response by Infectious Bronchitis Coronavirus

(2014) Joeri Kint et al.   JOURNAL OF VIROLOGY

Middle East Respiratory Syndrome Coronavirus 4a Protein Is a Double-Stranded RNA-Binding Protein That Suppresses PACT-Induced Activation of RIG-I and MDA5 in the Innate Antiviral Response

(2014) K.-L. Siu et al.   JOURNAL OF VIROLOGY

The avian coronavirus spike protein

(2014) I.N. Ambepitiya Wickramasinghe et al.   VIRUS RESEARCH

The Coronavirus Nucleocapsid Is a Multifunctional Protein

(2014) Ruth McBride et al.   Viruses-Basel

The Laboratory of Genetics and Physiology 2: Emerging Insights into the Controversial Functions of This RIG-I-Like Receptor

(2014) Zixiang Zhu et al.   Biomed Research International

Pattern Recognition and Signaling Mechanisms of RIG-I and MDA5

(2014) Stephanie Reikine et al.   Frontiers in Immunology

Chicken MDA5 Senses Short Double-Stranded RNA with Implications for Antiviral Response against Avian Influenza Viruses in Chicken

(2013) Tsuyoshi Hayashi et al.   Journal of Innate Immunity

Middle East Respiratory Syndrome Coronavirus Accessory Protein 4a Is a Type I Interferon Antagonist

(2013) D. Niemeyer et al.   JOURNAL OF VIROLOGY

The long view: 40 years of infectious bronchitis research

(2012) Jane K. A. Cook et al.   AVIAN PATHOLOGY

Critical Roles of Glucocorticoid-Induced Leucine Zipper in Infectious Bursal Disease Virus (IBDV)-Induced Suppression of Type I Interferon Expression and Enhancement of IBDV Growth in Host Cells via Interaction with VP4

(2012) Z. Li et al.   JOURNAL OF VIROLOGY

The Double-Stranded RNA-Binding Protein PACT Functions as a Cellular Activator of RIG-I to Facilitate Innate Antiviral Response

(2011) Kin-Hang Kok et al.   Cell Host & Microbe

Immune Signaling by RIG-I-like Receptors

(2011) Yueh-Ming Loo et al.   IMMUNITY

Characterization of Chicken Mda5 Activity: Regulation of IFN-  in the Absence of RIG-I Functionality

(2011) A. J. Karpala et al.   JOURNAL OF IMMUNOLOGY

Cell-Type-Specific Type I Interferon Antagonism Influences Organ Tropism of Murine Coronavirus

(2011) L. Zhao et al.   JOURNAL OF VIROLOGY

Chicken Cells Sense Influenza A Virus Infection through MDA5 and CARDIF Signaling Involving LGP2

(2011) M. Liniger et al.   JOURNAL OF VIROLOGY

RIG-I like receptors and their signaling crosstalk in the regulation of antiviral immunity

(2011) Hilario J Ramos et al.   Current Opinion in Virology

Association of RIG-I with innate immunity of ducks to influenza

(2010) M. R. W. Barber et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

SARS-CoV nucleocapsid protein antagonizes IFN-β response by targeting initial step of IFN-β induction pathway, and its C-terminal region is critical for the antagonism

(2010) Xiaolu Lu et al.   VIRUS GENES

Growth performance and immune responses in chickens after challenge with lipopolysaccharide and modulation by dietary different oils

(2008) X. Yang et al.   Animal

MDA5/RIG-I and virus recognition

(2008) Osamu Takeuchi et al.   CURRENT OPINION IN IMMUNOLOGY

Multiple Nucleic Acid Binding Sites and Intrinsic Disorder of Severe Acute Respiratory Syndrome Coronavirus Nucleocapsid Protein: Implications for Ribonucleocapsid Protein Packaging

(2008) C.-K. Chang et al.   JOURNAL OF VIROLOGY

Murine Coronavirus Mouse Hepatitis Virus Is Recognized by MDA5 and Induces Type I Interferon in Brain Macrophages/Microglia

(2008) J. K. Roth-Cross et al.   JOURNAL OF VIROLOGY

SARS coronavirus and innate immunity

(2007) Matthew Frieman et al.   VIRUS RESEARCH