Middle East Respiratory Syndrome Coronavirus 4a Protein Is a Double-Stranded RNA-Binding Protein That Suppresses PACT-Induced Activation of RIG-I and MDA5 in the Innate Antiviral Response
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Title
Middle East Respiratory Syndrome Coronavirus 4a Protein Is a Double-Stranded RNA-Binding Protein That Suppresses PACT-Induced Activation of RIG-I and MDA5 in the Innate Antiviral Response
Authors
Keywords
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Journal
JOURNAL OF VIROLOGY
Volume 88, Issue 9, Pages 4866-4876
Publisher
American Society for Microbiology
Online
2014-02-13
DOI
10.1128/jvi.03649-13
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Note: Only part of the references are listed.- Suppression of innate antiviral response by severe acute respiratory syndrome coronavirus M protein is mediated through the first transmembrane domain
- (2014) Kam-Leung Siu et al. Cellular & Molecular Immunology
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- Seroepidemiology for MERS coronavirus using microneutralisation and pseudoparticle virus neutralisation assays reveal a high prevalence of antibody in dromedary camels in Egypt, June 2013
- (2013) R Perera et al. Eurosurveillance
- Cytosolic Sensing of Viruses
- (2013) Delphine Goubau et al. IMMUNITY
- Delayed induction of proinflammatory cytokines and suppression of innate antiviral response by the novel Middle East respiratory syndrome coronavirus: implications for pathogenesis and treatment
- (2013) S. K. P. Lau et al. JOURNAL OF GENERAL VIROLOGY
- MERS-coronavirus replication induces severe in vitro cytopathology and is strongly inhibited by cyclosporin A or interferon- treatment
- (2013) A. H. de Wilde et al. JOURNAL OF GENERAL VIROLOGY
- Differential Cell Line Susceptibility to the Emerging Novel Human Betacoronavirus 2c EMC/2012: Implications for Disease Pathogenesis and Clinical Manifestation
- (2013) Jasper Fuk-Woo Chan, Kwok-Hung Chan, Garnet Kwan-Yue Choi, Kelvin Kai-Wang To, Herman Tse, Jian-Piao Cai et al. JOURNAL OF INFECTIOUS DISEASES
- Active Replication of Middle East Respiratory Syndrome Coronavirus and Aberrant Induction of Inflammatory Cytokines and Chemokines in Human Macrophages: Implications for Pathogenesis
- (2013) Jie Zhou et al. JOURNAL OF INFECTIOUS DISEASES
- The emerging novel Middle East respiratory syndrome coronavirus: The “knowns” and “unknowns”
- (2013) Jasper Fuk-Woo Chan et al. JOURNAL OF THE FORMOSAN MEDICAL ASSOCIATION
- Genetic Characterization of Betacoronavirus Lineage C Viruses in Bats Reveals Marked Sequence Divergence in the Spike Protein of Pipistrellus Bat Coronavirus HKU5 in Japanese Pipistrelle: Implications for the Origin of the Novel Middle East Respiratory Syndrome Coronavirus
- (2013) S. K. P. Lau et al. JOURNAL OF VIROLOGY
- Tropism of and Innate Immune Responses to the Novel Human Betacoronavirus Lineage C Virus in Human Ex Vivo Respiratory Organ Cultures
- (2013) R. W. Y. Chan et al. JOURNAL OF VIROLOGY
- Suppression of PACT-Induced Type I Interferon Production by Herpes Simplex Virus 1 Us11 Protein
- (2013) C. Kew et al. JOURNAL OF VIROLOGY
- Human Cell Tropism and Innate Immune System Interactions of Human Respiratory Coronavirus EMC Compared to Those of Severe Acute Respiratory Syndrome Coronavirus
- (2013) F. Zielecki et al. JOURNAL OF VIROLOGY
- Middle East Respiratory Syndrome Coronavirus Accessory Protein 4a Is a Type I Interferon Antagonist
- (2013) D. Niemeyer et al. JOURNAL OF VIROLOGY
- Middle East Respiratory Syndrome Coronavirus (MERS-CoV): Announcement of the Coronavirus Study Group
- (2013) R. J. de Groot et al. JOURNAL OF VIROLOGY
- Interhuman transmissibility of Middle East respiratory syndrome coronavirus: estimation of pandemic risk
- (2013) Romulus Breban et al. LANCET
- Clinical features and viral diagnosis of two cases of infection with Middle East Respiratory Syndrome coronavirus: a report of nosocomial transmission
- (2013) Benoit Guery et al. LANCET
- Middle East respiratory syndrome coronavirus neutralising serum antibodies in dromedary camels: a comparative serological study
- (2013) Chantal BEM Reusken et al. LANCET INFECTIOUS DISEASES
- Treatment with interferon-α2b and ribavirin improves outcome in MERS-CoV–infected rhesus macaques
- (2013) Darryl Falzarano et al. NATURE MEDICINE
- Hospital Outbreak of Middle East Respiratory Syndrome Coronavirus
- (2013) Abdullah Assiri et al. NEW ENGLAND JOURNAL OF MEDICINE
- Family Cluster of Middle East Respiratory Syndrome Coronavirus Infections
- (2013) Ziad A. Memish et al. NEW ENGLAND JOURNAL OF MEDICINE
- Reverse genetics with a full-length infectious cDNA of the Middle East respiratory syndrome coronavirus
- (2013) T. Scobey et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Group I p21-activated kinases facilitate Tax-mediated transcriptional activation of the human T-cell leukemia virus type 1 long terminal repeats
- (2013) Ching-Ping Chan et al. Retrovirology
- LKB1 tumor suppressor and salt-inducible kinases negatively regulate human T-cell leukemia virus type 1 transcription
- (2013) Hei-Man Vincent Tang et al. Retrovirology
- Interspecies transmission and emergence of novel viruses: lessons from bats and birds
- (2013) Jasper Fuk-Woo Chan et al. TRENDS IN MICROBIOLOGY
- Detection of Coronaviruses in Bats of Various Species in Italy
- (2013) Davide Lelli et al. Viruses-Basel
- Engineering a Replication-Competent, Propagation-Defective Middle East Respiratory Syndrome Coronavirus as a Vaccine Candidate
- (2013) F. Almazan et al. mBio
- Efficient Replication of the Novel Human Betacoronavirus EMC on Primary Human Epithelium Highlights Its Zoonotic Potential
- (2013) E. Kindler et al. mBio
- The structural and accessory proteins M, ORF 4a, ORF 4b, and ORF 5 of Middle East respiratory syndrome coronavirus (MERS-CoV) are potent interferon antagonists
- (2013) Yang Yang et al. Protein & Cell
- Isolation of a Novel Coronavirus from a Man with Pneumonia in Saudi Arabia
- (2012) Ali M. Zaki et al. NEW ENGLAND JOURNAL OF MEDICINE
- Antiviral Immune Responses of Bats: A Review
- (2012) M. L. Baker et al. Zoonoses and Public Health
- Genomic Characterization of a Newly Discovered Coronavirus Associated with Acute Respiratory Distress Syndrome in Humans
- (2012) S. van Boheemen et al. mBio
- SARS coronavirus pathogenesis: host innate immune responses and viral antagonism of interferon
- (2012) Allison L Totura et al. Current Opinion in Virology
- The Double-Stranded RNA-Binding Protein PACT Functions as a Cellular Activator of RIG-I to Facilitate Innate Antiviral Response
- (2011) Kin-Hang Kok et al. Cell Host & Microbe
- Toll-like receptors
- (2011) Eva Marie Y. Moresco et al. CURRENT BIOLOGY
- MIP-T3 Is a Negative Regulator of Innate Type I IFN Response
- (2011) M.-H. J. Ng et al. JOURNAL OF IMMUNOLOGY
- Murine Coronavirus Induces Type I Interferon in Oligodendrocytes through Recognition by RIG-I and MDA5
- (2010) J. Li et al. JOURNAL OF VIROLOGY
- Severe Acute Respiratory Syndrome Coronavirus M Protein Inhibits Type I Interferon Production by Impeding the Formation of TRAF3·TANK·TBK1/IKKϵ Complex
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- Severe acute respiratory syndrome coronavirus nucleocapsid protein does not modulate transcription of the human FGL2 gene
- (2009) K.-L. Siu et al. JOURNAL OF GENERAL VIROLOGY
- The Ebola virus ribonucleoprotein complex: A novel VP30–L interaction identified
- (2008) A. Groseth et al. VIRUS RESEARCH
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