Cellular RNA Helicase DDX1 Is Involved in Transmissible Gastroenteritis Virus nsp14-Induced Interferon-Beta Production

The Severe Acute Respiratory Syndrome Coronavirus Nucleocapsid Inhibits Type I Interferon Production by Interfering with TRIM25-Mediated RIG-I Ubiquitination

(2017) Yong Hu et al.   JOURNAL OF VIROLOGY

Transmissible gastroenteritis virus does not suppress IFN-β induction but is sensitive to IFN in IPEC-J2 cells

(2017) Liqi Zhu et al.   VETERINARY MICROBIOLOGY

Venezuelan equine encephalitis virus non-structural protein 3 (nsP3) interacts with RNA helicases DDX1 and DDX3 in infected cells

(2016) Moushimi Amaya et al.   ANTIVIRAL RESEARCH

Mutagenesis of Coronavirus nsp14 Reveals Its Potential Role in Modulation of the Innate Immune Response

(2016) Martina Becares et al.   JOURNAL OF VIROLOGY

Porcine Epidemic Diarrhea Virus Infection Inhibits Interferon Signaling by Targeted Degradation of STAT1

(2016) Longjun Guo et al.   JOURNAL OF VIROLOGY

SARS and MERS: recent insights into emerging coronaviruses

(2016) Emmie de Wit et al.   NATURE REVIEWS MICROBIOLOGY

The Membrane Protein of Severe Acute Respiratory Syndrome Coronavirus Functions as a Novel Cytosolic Pathogen-Associated Molecular Pattern To Promote Beta Interferon Induction via a Toll-Like-Receptor-Related TRAF3-Independent Mechanism

(2016) Yi Wang et al.   mBio

Middle East respiratory syndrome coronavirus M protein suppresses type I interferon expression through the inhibition of TBK1-dependent phosphorylation of IRF3

(2016) Pak-Yin Lui et al.   Emerging Microbes & Infections

DEAD-box RNA helicase DDX3X inhibits DENV replication via regulating type one interferon pathway

(2015) Guanghao Li et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Infectious Bronchitis Coronavirus Inhibits STAT1 Signaling and Requires Accessory Proteins for Resistance to Type I Interferon Activity

(2015) Joeri Kint et al.   JOURNAL OF VIROLOGY

Porcine Epidemic Diarrhea Virus 3C-Like Protease Regulates Its Interferon Antagonism by Cleaving NEMO

(2015) Dang Wang et al.   JOURNAL OF VIROLOGY

Dengue virus NS1 protein activates cells via Toll-like receptor 4 and disrupts endothelial cell monolayer integrity

(2015) Naphak Modhiran et al.   Science Translational Medicine

Influenza A Virus Infection, Innate Immunity, and Childhood

(2015) Bria M. Coates et al.   JAMA Pediatrics

Reovirus Activates Human Dendritic Cells to Promote Innate Antitumor Immunity

(2014) Fiona Errington et al.   JOURNAL OF IMMUNOLOGY

Quantitative Proteomic Analysis Reveals That Transmissible Gastroenteritis Virus Activates the JAK-STAT1 Signaling Pathway

(2014) Kang An et al.   JOURNAL OF PROTEOME RESEARCH

Effects of virulent and attenuated transmissible gastroenteritis virus on the ability of porcine dendritic cells to sample and present antigen

(2014) Shanshan Zhao et al.   VETERINARY MICROBIOLOGY

Understanding the interaction of hepatitis C virus with host DEAD-box RNA helicases

(2014) Megha Haridas Upadya   WORLD JOURNAL OF GASTROENTEROLOGY

Herpes simplex virus 2–induced activation in vaginal cells involves Toll-like receptors 2 and 9 and DNA sensors DAI and IFI16

(2013) Kathy Triantafilou et al.   AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY

DExD/H-box RNA helicases as mediators of anti-viral innate immunity and essential host factors for viral replication

(2013) Anthony Fullam et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Rotavirus NSP4 Triggers Secretion of Proinflammatory Cytokines from Macrophages via Toll-Like Receptor 2

(2013) Y. Ge et al.   JOURNAL OF VIROLOGY

Alphacoronavirus Protein 7 Modulates Host Innate Immune Response

(2013) J. L. G. Cruz et al.   JOURNAL OF VIROLOGY

Encephalomyocarditis Virus Disrupts Stress Granules, the Critical Platform for Triggering Antiviral Innate Immune Responses

(2013) C. S. Ng et al.   JOURNAL OF VIROLOGY

Interferon-α Is the Primary Plasma Type-I IFN in HIV-1 Infection and Correlates with Immune Activation and Disease Markers

(2013) Gareth A. D. Hardy et al.   PLoS One

Respiratory Syncytial Virus Induced Type I IFN Production by pDC Is Regulated by RSV-Infected Airway Epithelial Cells, RSV-Exposed Monocytes and Virus Specific Antibodies

(2013) Marcel A. Schijf et al.   PLoS One

Cellular RNA helicases and HIV-1: Insights from genome-wide, proteomic, and molecular studies

(2012) Chia-Yen Chen et al.   VIRUS RESEARCH

DDX1, DDX21, and DHX36 Helicases Form a Complex with the Adaptor Molecule TRIF to Sense dsRNA in Dendritic Cells

(2011) Zhiqiang Zhang et al.   IMMUNITY

Newcastle disease virus induces pro-inflammatory conditions and type I interferon for counter-acting Treg activity

(2011) Volker Schirrmacher   INTERNATIONAL JOURNAL OF ONCOLOGY

DHX9 Pairs with IPS-1 To Sense Double-Stranded RNA in Myeloid Dendritic Cells

(2011) Z. Zhang et al.   JOURNAL OF IMMUNOLOGY

DDX1 Is an RNA-Dependent ATPase Involved in HIV-1 Rev Function and Virus Replication

(2011) Stephen P. Edgcomb et al.   JOURNAL OF MOLECULAR BIOLOGY

The helicase DDX41 senses intracellular DNA mediated by the adaptor STING in dendritic cells

(2011) Zhiqiang Zhang et al.   NATURE IMMUNOLOGY

Pattern Recognition Receptors and the Innate Immune Response to Viral Infection

(2011) Mikayla R. Thompson et al.   Viruses-Basel

RIG-I like receptors and their signaling crosstalk in the regulation of antiviral immunity

(2011) Hilario J Ramos et al.   Current Opinion in Virology

DEAD/H BOX 3 (DDX3) helicase binds the RIG-I adaptor IPS-1 to up-regulate IFN-β-inducing potential

(2010) Hiroyuki Oshiumi et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

The Cellular RNA Helicase DDX1 Interacts with Coronavirus Nonstructural Protein 14 and Enhances Viral Replication

(2010) L. Xu et al.   JOURNAL OF VIROLOGY

Murine Coronavirus Induces Type I Interferon in Oligodendrocytes through Recognition by RIG-I and MDA5

(2010) J. Li et al.   JOURNAL OF VIROLOGY

Small Interfering RNA Effectively Inhibits the Expression of SARS Coronavirus Membrane Gene at Two Novel Targeting Sites

(2010) Ying Wang et al.   MOLECULES

Aspartate-glutamate-alanine-histidine box motif (DEAH)/RNA helicase A helicases sense microbial DNA in human plasmacytoid dendritic cells

(2010) T. Kim et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Severe Acute Respiratory Syndrome Coronavirus M Protein Inhibits Type I Interferon Production by Impeding the Formation of TRAF3·TANK·TBK1/IKKϵ Complex

(2009) Kam-Leung Siu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

DDX3 DEAD-Box RNA Helicase Inhibits Hepatitis B Virus Reverse Transcription by Incorporation into Nucleocapsids

(2009) H. Wang et al.   JOURNAL OF VIROLOGY

Murine Coronavirus Cell Type Dependent Interaction with the Type I Interferon Response

(2009) Kristine Rose et al.   Viruses-Basel

Viral targeting of DEAD box protein 3 reveals its role in TBK1/IKKɛ-mediated IRF activation

(2008) Martina Schröder et al.   EMBO JOURNAL

RNA interference screen for human genes associated with West Nile virus infection

(2008) Manoj N. Krishnan et al.   NATURE

Molecular cloning and functional characterization of porcine IFN-β promoter stimulator 1 (IPS-1)

(2008) Dang Wang et al.   VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY

Interferons and viruses: an interplay between induction, signalling, antiviral responses and virus countermeasures

(2007) R. E. Randall et al.   JOURNAL OF GENERAL VIROLOGY