The effects of ALK5 inhibition and simultaneous inhibition or activation of HIF-1α in melanoma tumor growth and angiogenesis
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Title
The effects of ALK5 inhibition and simultaneous inhibition or activation of HIF-1α in melanoma tumor growth and angiogenesis
Authors
Keywords
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Journal
TUMOR BIOLOGY
Volume 45, Issue 1, Pages 111-126
Publisher
IOS Press
Online
2023-11-01
DOI
10.3233/tub-220020
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Note: Only part of the references are listed.- Melanoma, Melanin, and Melanogenesis: The Yin and Yang Relationship
- (2022) Radomir M. Slominski et al. Frontiers in Oncology
- The Synergistic Cooperation between TGF-β and Hypoxia in Cancer and Fibrosis
- (2022) Pramod Mallikarjuna et al. Biomolecules
- The role of hypoxia in the tumor microenvironment and development of cancer stem cell: a novel approach to developing treatment
- (2021) Asieh Emami Nejad et al. Cancer Cell International
- The role of Hypoxia-Inducible Factor-1alpha and its signaling in melanoma
- (2021) Mohammad Malekan et al. BIOMEDICINE & PHARMACOTHERAPY
- Progression of melanoma is suppressed by targeting all transforming growth factor‑β isoforms with an Fc chimeric receptor
- (2021) Shingo Kodama et al. ONCOLOGY REPORTS
- Therapeutic implications of cancer epithelial-mesenchymal transition (EMT)
- (2019) Eunae Sandra Cho et al. ARCHIVES OF PHARMACAL RESEARCH
- HIF Inhibitors: Status of Current Clinical Development
- (2019) Jaleh Fallah et al. Current Oncology Reports
- The double edge sword of fibrosis in cancer
- (2019) Chelsea Chandler et al. Translational Research
- Interactions between TGF-β type I receptor and hypoxia-inducible factor-α mediates a synergistic crosstalk leading to poor prognosis for patients with clear cell renal cell carcinoma
- (2019) Pramod Mallikarjuna et al. CELL CYCLE
- Limitations of Anti-Angiogenic Treatment of Tumors
- (2019) Domenico Ribatti et al. Translational Oncology
- STAT3 aggravates TGF-β1-induced hepatic epithelial-to-mesenchymal transition and migration
- (2018) Bin Wang et al. BIOMEDICINE & PHARMACOTHERAPY
- TGF-beta signaling in cancer: post-transcriptional regulation of EMT via hnRNP E1
- (2018) Breege V. Howley et al. CYTOKINE
- The hypoxic tumour microenvironment
- (2018) Varvara Petrova et al. Oncogenesis
- Hypoxia-Inducible Factor 1α Regulates the Transforming Growth Factor β1/SMAD Family Member 3 Pathway to Promote Breast Cancer Progression
- (2018) Jianheng Peng et al. Journal of Breast Cancer
- Combined Inhibition of DYRK1A, SMAD, and Trithorax Pathways Synergizes to Induce Robust Replication in Adult Human Beta Cells
- (2018) Peng Wang et al. Cell Metabolism
- Therapeutic targeting of angiogenesis molecular pathways in angiogenesis-dependent diseases
- (2018) Asghar Fallah et al. BIOMEDICINE & PHARMACOTHERAPY
- Inhibition of microRNA-21 via locked nucleic acid-anti-miR suppressed metastatic features of colorectal cancer cells through modulation of programmed cell death 4
- (2017) Reza Nedaeinia et al. TUMOR BIOLOGY
- TGF-β Signaling from Receptors to Smads
- (2016) Akiko Hata et al. Cold Spring Harbor Perspectives in Biology
- Melanin content in melanoma metastases affects the outcome of radiotherapy
- (2016) Anna A. Brożyna et al. Oncotarget
- Inhibition of TGFβ type I receptor activity facilitates liver regeneration upon acute CCl4 intoxication in mice
- (2015) Sofia Karkampouna et al. ARCHIVES OF TOXICOLOGY
- Driving the Hypoxia-Inducible Pathway in Human Pericytes Promotes Vascular Density in an Exosome-Dependent Manner
- (2015) Jamie N. Mayo et al. MICROCIRCULATION
- HIF-1α Promotes Epithelial-Mesenchymal Transition and Metastasis through Direct Regulation of ZEB1 in Colorectal Cancer
- (2015) Wenjing Zhang et al. PLoS One
- Potent and Selective Triazole-Based Inhibitors of the Hypoxia-Inducible Factor Prolyl-Hydroxylases with Activity in the Murine Brain
- (2015) Mun Chiang Chan et al. PLoS One
- The Paradox of E-Cadherin: Role in response to hypoxia in the tumor microenvironment and regulation of energy metabolism
- (2015) Khoi Chu et al. Oncotarget
- The role of melanogenesis in regulation of melanoma behavior: Melanogenesis leads to stimulation of HIF-1α expression and HIF-dependent attendant pathways
- (2014) A. Slominski et al. ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
- Developmental pathways activated in melanocytes and melanoma
- (2014) Jianglan Liu et al. ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
- A randomized, open-label clinical trial of tasisulam sodium versus paclitaxel as second-line treatment in patients with metastatic melanoma
- (2014) Omid Hamid et al. CANCER
- Inhibition of hypoxia-inducible factors limits tumor progression in a mouse model of colorectal cancer
- (2014) Jessica E.S. Shay et al. CARCINOGENESIS
- Molecular Pathways: Can Activin-like Kinase Pathway Inhibition Enhance the Limited Efficacy of VEGF Inhibitors?
- (2014) R. S. Bhatt et al. CLINICAL CANCER RESEARCH
- The potential role of HIF on tumour progression and dissemination
- (2014) Sandeep Unwith et al. INTERNATIONAL JOURNAL OF CANCER
- TGF- : Duality of Function Between Tumor Prevention and Carcinogenesis
- (2014) D. R. Principe et al. JNCI-Journal of the National Cancer Institute
- Insights into the Transforming Growth Factor-β Signaling Pathway in Cutaneous Melanoma
- (2013) Carole Yolande Perrot et al. Annals of Dermatology
- Hypoxia-Induced Secretion of TGF-β1 in Mesenchymal Stem Cell Promotes Breast Cancer Cell Progression
- (2013) Shun-Pei Hung et al. CELL TRANSPLANTATION
- Melanoma epidemiology, biology and prognosis
- (2013) Z. Ali et al. EJC SUPPLEMENTS
- Activin receptor-like kinase5 inhibition suppresses mouse melanoma by ubiquitin degradation of Smad4, thereby derepressing eomesodermin in cytotoxic T lymphocytes
- (2013) Jeong-Hwan Yoon et al. EMBO Molecular Medicine
- Molecular biology of normal melanocytes and melanoma cells
- (2013) Bizhan Bandarchi et al. JOURNAL OF CLINICAL PATHOLOGY
- Activin Receptor-Like Kinase 1: a Novel Anti-angiogenesis Target from TGF-β Family
- (2013) Luca Vecchia et al. MINI-REVIEWS IN MEDICINAL CHEMISTRY
- Why is melanoma so metastatic?
- (2013) Russell R. Braeuer et al. Pigment Cell & Melanoma Research
- Intratumor Hypoxia Promotes Immune Tolerance by Inducing Regulatory T Cells via TGF-β1 in Gastric Cancer
- (2013) Bin Deng et al. PLoS One
- CD44 Expressed on Cancer-Associated Fibroblasts Is a Functional Molecule Supporting the Stemness and Drug Resistance of Malignant Cancer Cells in the Tumor Microenvironment
- (2013) Yumi Kinugasa et al. STEM CELLS
- Inhibition of Breast Cancer Metastases by a Novel Inhibitor of TGFβ Receptor 1
- (2012) Yuanzhang Fang et al. JNCI-Journal of the National Cancer Institute
- Uncovering the role of hypoxia inducible factor-1α in skin carcinogenesis
- (2011) Kris Nys et al. BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER
- Epithelial-Mesenchymal Transition-Derived Cells Exhibit Multilineage Differentiation Potential Similar to Mesenchymal Stem Cells
- (2010) Venkata Lokesh Battula et al. STEM CELLS
- Targeting angiogenesis in melanoma: prospects for the future
- (2010) P.G. Corrie et al. Therapeutic Advances in Medical Oncology
- Hypoxia and TGF-β Drive Breast Cancer Bone Metastases through Parallel Signaling Pathways in Tumor Cells and the Bone Microenvironment
- (2009) Lauren K. Dunn et al. PLoS One
- Inhibition of endogenous TGF- signaling enhances lymphangiogenesis
- (2008) M. Oka et al. BLOOD
- Transforming growth factor-β in cutaneous melanoma
- (2008) Delphine Javelaud et al. Pigment Cell & Melanoma Research
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