Molecular engineering of insulin for recombinant expression in yeast
Published 2023 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Molecular engineering of insulin for recombinant expression in yeast
Authors
Keywords
-
Journal
TRENDS IN BIOTECHNOLOGY
Volume -, Issue -, Pages -
Publisher
Elsevier BV
Online
2023-10-24
DOI
10.1016/j.tibtech.2023.09.012
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Challenges and progress towards industrial recombinant protein production in yeasts: A review
- (2023) Pieter De Brabander et al. BIOTECHNOLOGY ADVANCES
- Identification of stabilizing point mutations through mutagenesis of destabilized protein libraries
- (2022) Shahbaz Ahmed et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Improving recombinant protein production by yeast through genome-scale modeling using proteome constraints
- (2022) Feiran Li et al. Nature Communications
- Derivatization with fatty acids in peptide and protein drug discovery
- (2022) Peter Kurtzhals et al. NATURE REVIEWS DRUG DISCOVERY
- Biopharmaceutical benchmarks 2022
- (2022) Gary Walsh et al. NATURE BIOTECHNOLOGY
- Characterization of insulin crystalline form in isolated β-cell secretory granules
- (2022) Seiya Asai et al. Open Biology
- Current and future therapies for type 1 diabetes
- (2021) Bernt Johan von Scholten et al. DIABETOLOGIA
- The future of insulin therapy
- (2021) Tim Heise DIABETES RESEARCH AND CLINICAL PRACTICE
- 100 years of physiology, discrimination and wonder
- (2021) David Russell‐Jones et al. DIABETIC MEDICINE
- Commemorating insulin's centennial: engineering insulin pharmacology towards physiology
- (2021) Peter Kurtzhals et al. TRENDS IN PHARMACOLOGICAL SCIENCES
- “100 Years of progress in understanding insulin, its mechanism of action, and its roles in disease and diabetes therapy”
- (2021) C. Ronald Kahn Molecular Metabolism
- 100 years on: the impact of the discovery of insulin on clinical outcomes
- (2021) John B Buse et al. BMJ Open Diabetes Research & Care
- Molecular and pharmacological characterization of insulin icodec: a new basal insulin analog designed for once-weekly dosing
- (2021) Erica Nishimura et al. BMJ Open Diabetes Research & Care
- Cell free protein synthesis versus yeast expression – A comparison using insulin as a model protein
- (2021) Astrid B. Jensen et al. PROTEIN EXPRESSION AND PURIFICATION
- Insulin therapy development beyond 100 years
- (2021) Philip D Home et al. Lancet Diabetes & Endocrinology
- Once-Weekly Insulin for Type 2 Diabetes without Previous Insulin Treatment
- (2020) Julio Rosenstock et al. NEW ENGLAND JOURNAL OF MEDICINE
- Yeast Systems Biology: Model organism and Cell Factory
- (2019) Jens Nielsen Biotechnology Journal
- Yeast Expression Systems: Overview and Recent Advances
- (2019) Roghayyeh Baghban et al. MOLECULAR BIOTECHNOLOGY
- The integrative biology of type 2 diabetes
- (2019) Michael Roden et al. NATURE
- Directed evolution to improve protein folding in vivo
- (2018) Veronika Sachsenhauser et al. CURRENT OPINION IN STRUCTURAL BIOLOGY
- Continuous directed evolution of proteins with improved soluble expression
- (2018) Tina Wang et al. Nature Chemical Biology
- Insulin, glucagon and somatostatin stores in the pancreas of subjects with type-2 diabetes and their lean and obese non-diabetic controls
- (2017) Jean-Claude Henquin et al. Scientific Reports
- Prevention of cervical cancer: journey to develop the first human papillomavirus virus-like particle vaccine and the next generation vaccine
- (2016) Janine T Bryan et al. CURRENT OPINION IN CHEMICAL BIOLOGY
- Enthalpic and Entropic Contributions to Hydrophobicity
- (2016) Michael Schauperl et al. Journal of Chemical Theory and Computation
- Generation of glucagon-like peptide-2-expressingSaccharomyces cerevisiaeand its improvement of the intestinal health of weaned rats
- (2016) Zhongwei Zhang et al. Microbial Biotechnology
- Comparison of the pharmacokinetic and pharmacodynamic profiles of insulin degludec and insulin glargine
- (2015) Tim Heise et al. Expert Opinion on Drug Metabolism & Toxicology
- Pathophysiology of type 1 and type 2 diabetes mellitus: a 90-year perspective
- (2015) Francesco Zaccardi et al. POSTGRADUATE MEDICAL JOURNAL
- Additional disulfide bonds in insulin: Prediction, recombinant expression, receptor binding affinity, and stability
- (2015) Tine N. Vinther et al. PROTEIN SCIENCE
- Biopharmaceutical discovery and production in yeast
- (2014) Michael A Meehl et al. CURRENT OPINION IN BIOTECHNOLOGY
- Human serum albumin from recombinant DNA technology: Challenges and strategies
- (2013) Zhen Chen et al. BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS
- Long-term adaptation ofSaccharomyces cerevisiaeto the burden of recombinant insulin production
- (2013) Ali Kazemi Seresht et al. BIOTECHNOLOGY AND BIOENGINEERING
- PMT1 gene plays a major role in O-mannosylation of insulin precursor in Pichia pastoris
- (2013) Nagaraj Govindappa et al. PROTEIN EXPRESSION AND PURIFICATION
- Directed evolution of proteins for increased stability and expression using yeast display
- (2012) Michael W. Traxlmayr et al. ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
- Imbalance of heterologous protein folding and disulfide bond formation rates yields runaway oxidative stress
- (2012) Keith EJ Tyo et al. BMC BIOLOGY
- Systematic Evaluation of the Metabolic to Mitogenic Potency Ratio for B10-Substituted Insulin Analogues
- (2012) Tine Glendorf et al. PLoS One
- Novel Covalently Linked Insulin Dimer Engineered to Investigate the Function of Insulin Dimerization
- (2012) Tine N. Vinther et al. PLoS One
- Production of recombinant proteins by yeast cells
- (2011) Eda Çelik et al. BIOTECHNOLOGY ADVANCES
- Structural Analysis of Proinsulin Hexamer Assembly by Hydroxyl Radical Footprinting and Computational Modeling
- (2011) Janna G. Kiselar et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Engineering of Insulin Receptor Isoform-Selective Insulin Analogues
- (2011) Tine Glendorf et al. PLoS One
- Engineering of protein secretion in yeast: strategies and impact on protein production
- (2010) Alimjan Idiris et al. APPLIED MICROBIOLOGY AND BIOTECHNOLOGY
- Solution Structure of Proinsulin
- (2010) Yanwu Yang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- 10-Year Follow-up of Intensive Glucose Control in Type 2 Diabetes
- (2008) Rury R. Holman et al. NEW ENGLAND JOURNAL OF MEDICINE
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started