Cell free protein synthesis versus yeast expression – A comparison using insulin as a model protein

Constructive approach for synthesis of a functional IgG using a reconstituted cell-free protein synthesis system

(2019) Satoshi Murakami et al.   Scientific Reports

Insulin and its single-chain analogue

(2019) Ruifeng Mao et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Mutations at hypothetical binding site 2 in insulin and insulin-like growth factors 1 and 2 result in receptor- and hormone-specific responses

(2019) Kateřina Macháčková et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Biosynthesis, structure, and folding of the insulin precursor protein

(2018) Ming Liu et al.   DIABETES OBESITY & METABOLISM

Insulin in motion: The A6-A11 disulfide bond allosterically modulates structural transitions required for insulin activity

(2017) Bianca van Lierop et al.   Scientific Reports

Structure, Aggregation, and Activity of a Covalent Insulin Dimer Formed During Storage of Neutral Formulation of Human Insulin

(2016) Christian Fogt Hjorth et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Effects of localized interactions and surface properties on stability of protein-based therapeutics

(2016) Brittney J. Mills et al.   JOURNAL OF PHARMACY AND PHARMACOLOGY

Cell factories for insulin production

(2014) Nabih A Baeshen et al.   Microbial Cell Factories

Engine out of the chassis: Cell-free protein synthesis and its uses

(2013) Gabriel Rosenblum et al.   FEBS LETTERS

Novel Covalently Linked Insulin Dimer Engineered to Investigate the Function of Insulin Dimerization

(2012) Tine N. Vinther et al.   PLoS One

Identification of Anchor Points for Chemical Modification of a Small Cysteine-Rich Protein by Using a Cysteine Scan

(2011) Tine N. Vinther et al.   CHEMBIOCHEM

Features and development ofCoot

(2010) P. Emsley et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

PHENIX: a comprehensive Python-based system for macromolecular structure solution

(2010) Paul D. Adams et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Importance of the Solvent-Exposed Residues of the Insulin B Chain α-Helix for Receptor Binding†

(2008) Tine Glendorf et al.   BIOCHEMISTRY