Identification of stabilizing point mutations through mutagenesis of destabilized protein libraries

Prediction of Residue-specific Contributions to Binding and Thermal Stability Using Yeast Surface Display

(2022) Shahbaz Ahmed et al.   Frontiers in Molecular Biosciences

High-throughput developability assays enable library-scale identification of producible protein scaffold variants

(2021) Alexander W. Golinski et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

SARS-CoV-2 variant prediction and antiviral drug design are enabled by RBD in vitro evolution

(2021) Jiří Zahradník et al.   Nature Microbiology

A dual-reporter system for investigating and optimizing protein translation and folding in E. coli

(2021) Ariane Zutz et al.   Nature Communications

A Stabilized, Monomeric, Receptor Binding Domain Elicits High-Titer Neutralizing Antibodies Against All SARS-CoV-2 Variants of Concern

(2021) Shahbaz Ahmed et al.   Frontiers in Immunology

Deep mutational scanning of SARS-CoV-2 receptor binding domain reveals constraints on folding and ACE2 binding

(2020) Tyler N. Starr et al.   CELL

PremPS: Predicting the impact of missense mutations on protein stability

(2020) Yuting Chen et al.   PLoS Computational Biology

Phage Display: An Overview in Context to Drug Discovery

(2019) Selena Mimmi et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

DeepDDG: Predicting the Stability Change of Protein Point Mutations Using Neural Networks

(2019) Huali Cao et al.   Journal of Chemical Information and Modeling

Facile measurement of protein stability and folding kinetics using a nano differential scanning fluorimeter

(2019) Gopinath Chattopadhyay et al.   PROTEIN SCIENCE

Recent insights into the genotype‐phenotype relationship from massively‐parallel genetic assays

(2019) Harry Kemble et al.   Evolutionary Applications

Global analysis of protein folding using massively parallel design, synthesis, and testing

(2017) Gabriel J. Rocklin et al.   SCIENCE

INPS-MD: a web server to predict stability of protein variants from sequence and structure: Table 1.

(2016) Castrense Savojardo et al.   BIOINFORMATICS

Molecular Determinants of Mutant Phenotypes, Inferred from Saturation Mutagenesis Data

(2016) Arti Tripathi et al.   MOLECULAR BIOLOGY AND EVOLUTION

Automated Structure- and Sequence-Based Design of Proteins for High Bacterial Expression and Stability

(2016) Adi Goldenzweig et al.   MOLECULAR CELL

Residue proximity information and protein model discrimination using saturation-suppressor mutagenesis

(2015) Anusmita Sahoo et al.   eLife

A rapid, efficient, and economical inverse polymerase chain reaction-based method for generating a site saturation mutant library

(2013) Pankaj C. Jain et al.   ANALYTICAL BIOCHEMISTRY

PEAR: a fast and accurate Illumina Paired-End reAd mergeR

(2013) J. Zhang et al.   BIOINFORMATICS

Discovery of diverse and functional antibodies from large human repertoire antibody libraries

(2013) Lauren J. Schwimmer et al.   JOURNAL OF IMMUNOLOGICAL METHODS

Directed evolution of proteins for increased stability and expression using yeast display

(2012) Michael W. Traxlmayr et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

A fundamental protein property, thermodynamic stability, revealed solely from large-scale measurements of protein function

(2012) C. L. Araya et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

An enhanced approach for engineering thermally stable proteins using yeast display

(2012) T. V. Pavoor et al.   PROTEIN ENGINEERING DESIGN & SELECTION

Protein Model Discrimination Using Mutational Sensitivity Derived from Deep Sequencing

(2012) Bharat V. Adkar et al.   STRUCTURE

PoPMuSiC 2.1: a web server for the estimation of protein stability changes upon mutation and sequence optimality

(2011) Yves Dehouck et al.   BMC BIOINFORMATICS

High-resolution mapping of protein sequence-function relationships

(2010) Douglas M Fowler et al.   NATURE METHODS

Optimizing Protein Stability In Vivo

(2009) Linda Foit et al.   MOLECULAR CELL

Directed evolution drives the next generation of biocatalysts

(2009) Nicholas J Turner   Nature Chemical Biology

Directed evolution of an extremely stable fluorescent protein

(2009) C. Kiss et al.   PROTEIN ENGINEERING DESIGN & SELECTION

A Decade of Yeast Surface Display Technology: Where Are We Now?

(2008) Eric Shusta et al.   COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING