A protein-free vaccine stimulates innate immunity and protects against nosocomial pathogens

BCG Vaccination of Health Care Workers Does Not Reduce SARS-CoV-2 Infections nor Infection Severity or Duration: a Randomized Placebo-Controlled Trial

(2023) Juana Claus et al.   mBio

BCG vaccination provides protection against IAV but not SARS-CoV-2

(2022) Eva Kaufmann et al.   Cell Reports

Plasma metabolome predicts trained immunity responses after antituberculosis BCG vaccination

(2022) Valerie A. C. M. Koeken et al.   PLOS BIOLOGY

In vivo screens using a selective CRISPR antigen removal lentiviral vector system reveal immune dependencies in renal cell carcinoma

(2021) Juan Dubrot et al.   IMMUNITY

A Combination of Polybacterial MV140 and Candida albicans V132 as a Potential Novel Trained Immunity-Based Vaccine for Genitourinary Tract Infections

(2021) Leticia Martin-Cruz et al.   Frontiers in Immunology

Cytokine measurements add value to clinical variables in predicting outcomes for Staphylococcus aureus bacteremia

(2021) Karen Tan et al.   BMC INFECTIOUS DISEASES

IFN-γ-dependent NK cell activation is essential to metastasis suppression by engineered Salmonella

(2021) Qiubin Lin et al.   Nature Communications

Monoclonal Antibody Requires Immunomodulation for Efficacy Against Acinetobacter baumannii Infection

(2021) Travis B Nielsen et al.   JOURNAL OF INFECTIOUS DISEASES

Antibiotics in the pipeline: a literature review (2017–2020)

(2021) Jaffar A. Al-Tawfiq et al.   INFECTION

C/EBPβ-Dependent Epigenetic Memory Induces Trained Immunity in Hematopoietic Stem Cells

(2020) Bérengère de Laval et al.   Cell Stem Cell

Activate: Randomized Clinical Trial of BCG Vaccination against Infection in the Elderly

(2020) Evangelos J. Giamarellos-Bourboulis et al.   CELL

The Role of Cell Metabolism in Innate Immune Memory

(2020) Anaisa Valido Ferreira et al.   Journal of Innate Immunity

Trained immunity, tolerance, priming and differentiation: distinct immunological processes

(2020) Maziar Divangahi et al.   NATURE IMMUNOLOGY

Humanized mouse models of immunological diseases and precision medicine

(2019) Leonard D. Shultz et al.   MAMMALIAN GENOME

Adjunctive transferrin to reduce the emergence of antibiotic resistance in Gram-negative bacteria

(2019) Brian M Luna et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Vaccines targeting Staphylococcus aureus skin and bloodstream infections require different composition

(2019) Brian M. Luna et al.   PLoS One

Natural history of Acinetobacter baumannii infection in mice

(2019) Brian M. Luna et al.   PLoS One

Antimicrobial-resistant pathogens associated with adult healthcare-associated infections: Summary of data reported to the National Healthcare Safety Network, 2015–2017

(2019) Lindsey M. Weiner-Lastinger et al.   INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY

BCG-Induced Cross-Protection and Development of Trained Immunity: Implication for Vaccine Design

(2019) Camila Covián et al.   Frontiers in Immunology

Trained Immunity Confers Broad-Spectrum Protection Against Bacterial Infections

(2019) Eleonora Ciarlo et al.   JOURNAL OF INFECTIOUS DISEASES

BCG Educates Hematopoietic Stem Cells to Generate Protective Innate Immunity against Tuberculosis

(2018) Eva Kaufmann et al.   CELL

Metabolic Induction of Trained Immunity through the Mevalonate Pathway

(2018) Siroon Bekkering et al.   CELL

Histone methylation and acetylation in macrophages as a mechanism for regulation of inflammatory responses

(2018) Maria G. Daskalaki et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Analysis of length of hospital stay using electronic health records: A statistical and data mining approach

(2018) Hyunyoung Baek et al.   PLoS One

Induction of innate immune memory via microRNA targeting of chromatin remodelling factors

(2018) John J. Seeley et al.   NATURE

Prevalence of healthcare-associated infections, estimated incidence and composite antimicrobial resistance index in acute care hospitals and long-term care facilities: results from two European point prevalence surveys, 2016 to 2017

(2018) Carl Suetens et al.   Eurosurveillance

Changes in Prevalence of Health Care–Associated Infections in U.S. Hospitals

(2018) Shelley S. Magill et al.   NEW ENGLAND JOURNAL OF MEDICINE

Trained Immunity-Based Vaccines: A New Paradigm for the Development of Broad-Spectrum Anti-infectious Formulations

(2018) Silvia Sánchez-Ramón et al.   Frontiers in Immunology

Health care-associated infections – an overview

(2018) Mainul Haque et al.   Infection and Drug Resistance

Glutaminolysis and Fumarate Accumulation Integrate Immunometabolic and Epigenetic Programs in Trained Immunity

(2016) Rob J.W. Arts et al.   Cell Metabolism

OMIP-032: Two multi-color immunophenotyping panels for assessing the innate and adaptive immune cells in the mouse mammary gland

(2016) Ashleigh Unsworth et al.   CYTOMETRY PART A

deepTools2: a next generation web server for deep-sequencing data analysis

(2016) Fidel Ramírez et al.   NUCLEIC ACIDS RESEARCH

Myeloid Engraftment in Humanized Mice: Impact of Granulocyte-Colony Stimulating Factor Treatment and Transgenic Mouse Strain

(2016) Alice M. Coughlan et al.   STEM CELLS AND DEVELOPMENT

Non-invasive Imaging of Sendai Virus Infection in Pharmacologically Immunocompromised Mice: NK and T Cells, but not Neutrophils, Promote Viral Clearance after Therapy with Cyclophosphamide and Dexamethasone

(2016) Heba H. Mostafa et al.   PLoS Pathogens

Cryopreservation of virulent Acinetobacter baumannii to reduce variability of in vivo studies

(2015) Travis B. Nielsen et al.   BMC MICROBIOLOGY

A Dysregulated Balance of Proinflammatory and Anti-Inflammatory Host Cytokine Response Early During Therapy Predicts Persistence and Mortality in Staphylococcus aureus Bacteremia

(2015) Emi Minejima et al.   CRITICAL CARE MEDICINE

Gold Nanoparticle-Photosensitizer Conjugate Based Photodynamic Inactivation of Biofilm Producing Cells: Potential for Treatment of C. albicans Infection in BALB/c Mice

(2015) Mohd. Asif Sherwani et al.   PLoS One

Approaches for Preventing Healthcare-Associated Infections: Go Long or Go Wide?

(2014) Edward Septimus et al.   INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY

Epigenetic programming of monocyte-to-macrophage differentiation and trained innate immunity

(2014) S. Saeed et al.   SCIENCE

The Future of Antibiotics and Resistance

(2013) Brad Spellberg et al.   NEW ENGLAND JOURNAL OF MEDICINE

Economic burden of healthcare-associated infection in US acute care hospitals: societal perspective

(2013) Albert Marchetti et al.   JOURNAL OF MEDICAL ECONOMICS

Macrophage Killing of Bacterial and Fungal Pathogens Is Not Inhibited by Intense Intracellular Accumulation of the Lipoglycopeptide Antibiotic Oritavancin

(2012) Beverlie Baquir et al.   CLINICAL INFECTIOUS DISEASES

Identification of broadly protective human antibodies toPseudomonas aeruginosaexopolysaccharide Psl by phenotypic screening

(2012) Antonio DiGiandomenico et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Trained Immunity: A Memory for Innate Host Defense

(2011) Mihai G. Netea et al.   Cell Host & Microbe

Haplotype and isoform specific expression estimation using multi-mapping RNA-seq reads

(2011) Ernest Turro et al.   GENOME BIOLOGY

Infection control: the case for horizontal rather than vertical interventional programs

(2010) Richard P. Wenzel et al.   INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES

A unique chromatin signature uncovers early developmental enhancers in humans

(2010) Alvaro Rada-Iglesias et al.   NATURE

Antifungal Activity of Colistin against Mucorales Species In Vitro and in a Murine Model of Rhizopus oryzae Pulmonary Infection

(2009) R. Ben-Ami et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

The Sequence Alignment/Map format and SAMtools

(2009) H. Li et al.   BIOINFORMATICS

Fast and accurate short read alignment with Burrows-Wheeler transform

(2009) H. Li et al.   BIOINFORMATICS

Ultrafast and memory-efficient alignment of short DNA sequences to the human genome

(2009) Ben Langmead et al.   GENOME BIOLOGY

The Antifungal Vaccine Derived from the Recombinant N Terminus of Als3p Protects Mice against the Bacterium Staphylococcus aureus

(2008) B. Spellberg et al.   INFECTION AND IMMUNITY

Model-based Analysis of ChIP-Seq (MACS)

(2008) Yong Zhang et al.   GENOME BIOLOGY