MyoD-family inhibitor proteins act as auxiliary subunits of Piezo channels

Tethering Piezo channels to the actin cytoskeleton for mechanogating via the cadherin-β-catenin mechanotransduction complex

(2022) Jing Wang et al.   Cell Reports

Structure deformation and curvature sensing of PIEZO1 in lipid membranes

(2022) Xuzhong Yang et al.   NATURE

Pathogenic variants in MDFIC cause recessive central conducting lymphatic anomaly with lymphedema

(2022) Alicia B. Byrne et al.   Science Translational Medicine

Membrane curvature governs the distribution of Piezo1 in live cells

(2022) Shilong Yang et al.   Nature Communications

Piezo1 as a force-through-membrane sensor in red blood cells

(2022) George Vaisey et al.   eLife

Force- and cell state–dependent recruitment of Piezo1 drives focal adhesion dynamics and calcium entry

(2022) Mingxi Yao et al.   Science Advances

Protein S‐Palmitoylation: Advances and Challenges in Studying a Therapeutically Important Lipid Modification

(2021) Alice Main et al.   FEBS Journal

Piezo1 and BKCa channels in human atrial fibroblasts: Interplay and remodelling in atrial fibrillation

(2021) Dorothee Jakob et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Highly accurate protein structure prediction with AlphaFold

(2021) John Jumper et al.   NATURE

A single–cell type transcriptomics map of human tissues

(2021) Max Karlsson et al.   Science Advances

Piezo1 and Piezo2 foster mechanical gating of K2P channels

(2021) Edyta Glogowska et al.   Cell Reports

Spatiotemporal dynamics of PIEZO1 localization controls keratinocyte migration during wound healing

(2021) Jesse R Holt et al.   eLife

Adipocyte Piezo1 mediates obesogenic adipogenesis through the FGF1/FGFR1 signaling pathway in mice

(2020) ShengPeng Wang et al.   Nature Communications

UCSF ChimeraX : Structure visualization for researchers, educators, and developers

(2020) Eric F. Pettersen et al.   PROTEIN SCIENCE

Sphingomyelinase Disables Inactivation in Endogenous PIEZO1 Channels

(2020) Jian Shi et al.   Cell Reports

A hydrophobic gate in the inner pore helix is the major determinant of inactivation in mechanosensitive Piezo channels

(2019) Wang Zheng et al.   eLife

Dietary fatty acids fine-tune Piezo1 mechanical response

(2019) Luis O. Romero et al.   Nature Communications

Mechanically activated Piezo1 channels of cardiac fibroblasts stimulate p38 mitogen-activated protein kinase activity and interleukin-6 secretion

(2019) Nicola M. Blythe et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Voltage gating of mechanosensitive PIEZO channels

(2018) Mirko Moroni et al.   Nature Communications

TMEM150C/Tentonin3 Is a Regulator of Mechano-gated Ion Channels

(2018) Evan O. Anderson et al.   Cell Reports

Piezo1 forms a slowly-inactivating mechanosensory channel in mouse embryonic stem cells

(2018) Josefina Inés del Mármol et al.   eLife

Mechanically activated ion channel PIEZO1 is required for lymphatic valve formation

(2018) Keiko Nonomura et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

New tools for automated high-resolution cryo-EM structure determination in RELION-3

(2018) Jasenko Zivanov et al.   eLife

cryoSPARC: algorithms for rapid unsupervised cryo-EM structure determination

(2017) Ali Punjani et al.   NATURE METHODS

Precision genome editing using synthesis-dependent repair of Cas9-induced DNA breaks

(2017) Alexandre Paix et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Inactivation of Mechanically Activated Piezo1 Ion Channels Is Determined by the C-Terminal Extracellular Domain and the Inner Pore Helix

(2017) Jason Wu et al.   Cell Reports

Voltage-gated calcium channels and their auxiliary subunits: physiology and pathophysiology and pharmacology

(2016) Annette C. Dolphin   JOURNAL OF PHYSIOLOGY-LONDON

CHARMM36m: an improved force field for folded and intrinsically disordered proteins

(2016) Jing Huang et al.   NATURE METHODS

Removal of the mechanoprotective influence of the cytoskeleton reveals PIEZO1 is gated by bilayer tension

(2016) Charles D. Cox et al.   Nature Communications

Piezo1 Channels Are Inherently Mechanosensitive

(2016) Ruhma Syeda et al.   Cell Reports

GPS-Lipid: a robust tool for the prediction of multiple lipid modification sites

(2016) Yubin Xie et al.   Scientific Reports

GATA2 is required for lymphatic vessel valve development and maintenance

(2015) Jan Kazenwadel et al.   JOURNAL OF CLINICAL INVESTIGATION

Novel mutations in PIEZO1 cause an autosomal recessive generalized lymphatic dysplasia with non-immune hydrops fetalis

(2015) Elisavet Fotiou et al.   Nature Communications

Chemical activation of the mechanotransduction channel Piezo1

(2015) Ruhma Syeda et al.   eLife

Mechanosensitive Ca2+permeant cation channels in human prostate tumor cells

(2012) Rosario Maroto et al.   Channels

Defined criteria for auxiliary subunits of glutamate receptors

(2011) Dan Yan et al.   JOURNAL OF PHYSIOLOGY-LONDON

Piezo1 and Piezo2 Are Essential Components of Distinct Mechanically Activated Cation Channels

(2010) B. Coste et al.   SCIENCE

CHARMM-GUI: A web-based graphical user interface for CHARMM

(2008) Sunhwan Jo et al.   JOURNAL OF COMPUTATIONAL CHEMISTRY