The Health Benefiting Mechanisms of Virgin Olive Oil Phenolic Compounds

Metabolic disposition and biological significance of simple phenols of dietary origin: hydroxytyrosol and tyrosol

(2016) Jose Rodríguez-Morató et al.   DRUG METABOLISM REVIEWS

High quality, good health: The case for olive oil

(2016) Elena Bernardini et al.   EUROPEAN JOURNAL OF LIPID SCIENCE AND TECHNOLOGY

Cytotoxic Activity of Oleocanthal Isolated from Virgin Olive Oil on Human Melanoma Cells

(2016) Stefano Fogli et al.   NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL

(-)-Oleocanthal inhibits growth and metastasis by blocking activation of STAT3 in human hepatocellular carcinoma

(2016) Tiemin Pei et al.   Oncotarget

Mediterranean Diet and Its Association With Reduced Invasive Breast Cancer Risk

(2016) Franco Berrino   JAMA Oncology

Oleocanthal Enhances Amyloid-β Clearance from the Brains of TgSwDI Mice and in Vitro across a Human Blood-Brain Barrier Model

(2015) Hisham Qosa et al.   ACS Chemical Neuroscience

Mediterranean Dietary Patterns and Cardiovascular Health

(2015) Jia Shen et al.   Annual Review of Nutrition

Abstract 1889: Paleolithic and Mediterranean diet pattern scores and their associations with biomarkers of inflammation and oxidative balance

(2015) Kristine Whalen et al.   CANCER RESEARCH

Homeostasis, Inflammation, and Disease Susceptibility

(2015) Maya E. Kotas et al.   CELL

Olive Oil Polyphenols Decrease LDL Concentrations and LDL Atherogenicity in Men in a Randomized Controlled Trial

(2015) Álvaro Hernáez et al.   JOURNAL OF NUTRITION

Olive oil phenolic extract regulates interleukin-8 expression by transcriptional and posttranscriptional mechanisms in Caco-2 cells

(2015) Eri Muto et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Protective effect of hydroxytyrosol and its predominant plasmatic human metabolites against endothelial dysfunction in human aortic endothelial cells

(2015) Úrsula Catalán et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Olive Oil-derived Oleocanthal as Potent Inhibitor of Mammalian Target of Rapamycin: Biological Evaluation and Molecular Modeling Studies

(2015) Mohammad A. Khanfar et al.   PHYTOTHERAPY RESEARCH

Mediterranean Diet and Invasive Breast Cancer Risk Among Women at High Cardiovascular Risk in the PREDIMED Trial

(2015) Estefanía Toledo et al.   JAMA Internal Medicine

Additive Regulation of Adiponectin Expression by the Mediterranean Diet Olive Oil Components Oleic Acid and Hydroxytyrosol in Human Adipocytes

(2015) Egeria Scoditti et al.   PLoS One

Olive Phenolics as c-Met Inhibitors: (-)-Oleocanthal Attenuates Cell Proliferation, Invasiveness, and Tumor Growth in Breast Cancer Models

(2014) Mohamed R. Akl et al.   PLoS One

Mediterranean diet and non-fatal acute myocardial infarction: a case–control study from Italy

(2014) Federica Turati et al.   PUBLIC HEALTH NUTRITION

Oleuropein inhibits tumour growth and metastases dissemination in ovariectomised nude mice with MCF-7 human breast tumour xenografts

(2014) Maria Vittoria Sepporta et al.   Journal of Functional Foods

Olive-Oil-Derived Oleocanthal Enhances β-Amyloid Clearance as a Potential Neuroprotective Mechanism against Alzheimer’s Disease: In Vitro and in Vivo Studies

(2013) Alaa H. Abuznait et al.   ACS Chemical Neuroscience

Hydroxytyrosol suppresses MMP-9 and COX-2 activity and expression in activated human monocytes via PKCα and PKCβ1 inhibition

(2013) Egeria Scoditti et al.   ATHEROSCLEROSIS

Oleocanthal Inhibits Proliferation and MIP-1α Expression in Human Multiple Myeloma Cells

(2013) M. Scotece et al.   CURRENT MEDICINAL CHEMISTRY

Hydroxytyrosol prevents diet-induced metabolic syndrome and attenuates mitochondrial abnormalities in obese mice

(2013) Ke Cao et al.   FREE RADICAL BIOLOGY AND MEDICINE

Oleuropein and hydroxytyrosol activate GPER/ GPR30-dependent pathways leading to apoptosis of ER-negative SKBR3 breast cancer cells

(2013) Adele Chimento et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Primary Prevention of Cardiovascular Disease with a Mediterranean Diet

(2013) Ramón Estruch et al.   NEW ENGLAND JOURNAL OF MEDICINE

Protective role of the Mediterranean diet on several cardiovascular risk factors: Evidence from Sicily, southern Italy

(2013) G. Grosso et al.   NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES

Olive Oil Polyphenols Decrease Blood Pressure and Improve Endothelial Function in Young Women with Mild Hypertension

(2012) Rafael Moreno-Luna et al.   AMERICAN JOURNAL OF HYPERTENSION

Virgin olive oil in preventive medicine: From legend to epigenetics

(2012) Giuseppe Caramia et al.   EUROPEAN JOURNAL OF LIPID SCIENCE AND TECHNOLOGY

Influence of Mediterranean Diet on Asthma Symptoms, Lung Function, and Systemic Inflammation: A Randomized Controlled Trial

(2012) Paul Sexton et al.   JOURNAL OF ASTHMA

Further evidence for the anti-inflammatory activity of oleocanthal: Inhibition of MIP-1α and IL-6 in J774 macrophages and in ATDC5 chondrocytes

(2012) Morena Scotece et al.   LIFE SCIENCES

Virgin olive oil and nuts as key foods of the Mediterranean diet effects on inflammatory biomarkers related to atherosclerosis

(2012) Mireia Urpi-Sarda et al.   PHARMACOLOGICAL RESEARCH

Antimicrobial, antioxidant and anti-inflammatory phenolic activities in extra virgin olive oil

(2011) S Cicerale et al.   CURRENT OPINION IN BIOTECHNOLOGY

Oleuropein and hydroxytyrosol inhibit adipocyte differentiation in 3 T3-L1 cells

(2011) Riadh Drira et al.   LIFE SCIENCES

The postprandial inflammatory response after ingestion of heated oils in obese persons is reduced by the presence of phenol compounds

(2011) A. Perez-Herrera et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Dietary constituents reduce lipid accumulation in murine C3H10 T1/2 adipocytes: A novel fluorescent method to quantify fat droplets

(2011) Ines Warnke et al.   Nutrition & Metabolism

Mediterranean diet pyramid today. Science and cultural updates

(2011) Anna Bach-Faig et al.   PUBLIC HEALTH NUTRITION

New insights on the interaction mechanism between tau protein and oleocanthal, an extra-virgin olive-oil bioactive component

(2011) Maria Chiara Monti et al.   Food & Function

Exploratory analysis of human urine by LC–ESI-TOF MS after high intake of olive oil: understanding the metabolism of polyphenols

(2010) Rocío García-Villalba et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Effect of oleocanthal and its derivatives on inflammatory response induced by lipopolysaccharide in a murine chondrocyte cell line

(2010) Anna Iacono et al.   ARTHRITIS AND RHEUMATISM

Relationship between Mediterranean Diet Score and atherothrombotic risk: Findings from the Third National Health and Nutrition Examination Survey (NHANES III), 1988–1994

(2010) Stephanie J. Carter et al.   ATHEROSCLEROSIS

In vivo nutrigenomic effects of virgin olive oil polyphenols within the frame of the Mediterranean diet: a randomized controlled trial

(2010) Valentini Konstantinidou et al.   FASEB JOURNAL

Olive Oil Phenols Modulate the Expression of Metalloproteinase 9 in THP-1 Cells by Acting on Nuclear Factor-κB Signaling

(2010) Mario Dell’Agli et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Hydroxytyrosol inhibits growth and cell proliferation and promotes high expression of sfrp4 in rat mammary tumours

(2010) Sergio Granados-Principal et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Mediterranean diet and the incidence of cardiovascular disease: A Spanish cohort

(2010) M.A. Martínez-González et al.   NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES

Anti-proliferative and apoptotic effects of oleuropein and hydroxytyrosol on human breast cancer MCF-7 cells

(2009) Junkyu Han et al.   CYTOTECHNOLOGY

Digestion stability and evaluation of the metabolism and transport of olive oil phenols in the human small-intestinal epithelial Caco-2/TC7 cell line

(2009) Aranzazu Soler et al.   FOOD CHEMISTRY

Interaction between Phenolics and Gut Microbiota: Role in Human Health

(2009) María V. Selma et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Inhibition of tau fibrillization by oleocanthal via reaction with the amino groups of tau

(2009) Wenkai Li et al.   JOURNAL OF NEUROCHEMISTRY

Phytochemicals in olive-leaf extracts and their antiproliferative activity against cancer and endothelial cells

(2009) Vlassios Goulas et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Alzheimer's-associated Aβ oligomers show altered structure, immunoreactivity and synaptotoxicity with low doses of oleocanthal

(2009) Jason Pitt et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Extra virgin olive oil phenolics: absorption, metabolism, and biological activities in the GI tract

(2009) G Corona et al.   TOXICOLOGY AND INDUSTRIAL HEALTH

Chemistry and Health of Olive Oil Phenolics

(2008) Sara Cicerale et al.   CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION

Effects of hydroxytyrosol-20 on carrageenan-induced acute inflammation and hyperalgesia in rats

(2008) Dezheng Gong et al.   PHYTOTHERAPY RESEARCH

Bioavailability of olive oil phenolic compounds in humans

(2008) R. de la Torre   INFLAMMOPHARMACOLOGY