Chelators as Antineuroblastomas Agents

Reversing oncogenic transformation with iron chelation

(2021) Gina Abdelaal et al.   Oncotarget

Iron-Chelation Treatment by Novel Thiosemicarbazone Targets Major Signaling Pathways in Neuroblastoma

(2021) Peter Macsek et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

The iron chelator Deferasirox causes severe mitochondrial swelling without depolarization due to a specific effect on inner membrane permeability

(2020) Esther M. Gottwald et al.   Scientific Reports

Metallomics for Alzheimer's disease treatment: Use of new generation of chelators combining metal-cation binding and transport properties

(2018) Cosimo Walter D'Acunto et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

High-Dose Deferoxamine Treatment Disrupts Intracellular Iron Homeostasis, Reduces Growth, and Induces Apoptosis in Metastatic and Nonmetastatic Breast Cancer Cell Lines

(2018) Khuloud Bajbouj et al.   TECHNOLOGY IN CANCER RESEARCH & TREATMENT

The anticancer effects of desferrioxamine on human breast adenocarcinoma and hepatocellular carcinoma cells

(2017) Osman Salis et al.   Cancer Biomarkers

Recent advances in cancer treatment by iron chelators

(2016) Vincent Corcé et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Iron chelator-induced apoptosis via the ER stress pathway in gastric cancer cells

(2016) Jung Lim Kim et al.   TUMOR BIOLOGY

Synthesis and biological activity evaluation of hydrazone derivatives based on a Tröger’s base skeleton

(2015) Robert Kaplánek et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Identification and Pharmacological Inactivation of the MYCN Gene Network as a Therapeutic Strategy for Neuroblastic Tumor Cells

(2014) Olesya Chayka et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Physical Interaction between MYCN Oncogene and Polycomb Repressive Complex 2 (PRC2) in Neuroblastoma

(2013) Daisy Corvetta et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Detection of MYCN amplification using blood plasma: noninvasive therapy evaluation and prediction of prognosis in neuroblastoma

(2013) Masato Kojima et al.   PEDIATRIC SURGERY INTERNATIONAL

Design of iron chelators with therapeutic application

(2012) Tao Zhou et al.   DALTON TRANSACTIONS

Cellular Iron Depletion Stimulates the JNK and p38 MAPK Signaling Transduction Pathways, Dissociation of ASK1-Thioredoxin, and Activation of ASK1

(2011) Yu Yu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cancer cell iron metabolism and the development of potent iron chelators as anti-tumour agents

(2008) D.R. Richardson et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

The International Neuroblastoma Risk Group (INRG) Staging System: An INRG Task Force Report

(2008) Tom Monclair et al.   JOURNAL OF CLINICAL ONCOLOGY