High-Dose Deferoxamine Treatment Disrupts Intracellular Iron Homeostasis, Reduces Growth, and Induces Apoptosis in Metastatic and Nonmetastatic Breast Cancer Cell Lines

Contrasting intra- and extracellular distribution of catalytic ferrous iron in ovalbumin-induced peritonitis

(2016) Fumiya Ito et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Deferoxamine-induced increase in the intracellular iron levels in highly aggressive breast cancer cells leads to increased cell migration by enhancing TNF-α-dependent NF-κB signaling and TGF-β signaling

(2016) Ping Liu et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Cancer cells with irons in the fire

(2015) Laura M. Bystrom et al.   FREE RADICAL BIOLOGY AND MEDICINE

Defective Autophagosome Formation in p53-Null Colorectal Cancer Reinforces Crocin-Induced Apoptosis

(2015) Amr Amin et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Regulation of cellular iron metabolism and its implications in lung cancer progression

(2014) Wei Xiong et al.   MEDICAL ONCOLOGY

Systemic and tumor level iron regulation in men with colorectal cancer: a case control study

(2014) Cenk K Pusatcioglu et al.   Nutrition & Metabolism

Iron Metabolism Regulates p53 Signaling through Direct Heme-p53 Interaction and Modulation of p53 Localization, Stability, and Function

(2014) Jia Shen et al.   Cell Reports

A Probable Risk Factor of Female Breast Cancer: Study on Benign and Malignant Breast Tissue Samples

(2013) Sohaila Rehman et al.   BIOLOGICAL TRACE ELEMENT RESEARCH

Modulation of intracellular iron metabolism by iron chelation affects chromatin remodeling proteins and corresponding epigenetic modifications in breast cancer cells and increases their sensitivity to chemotherapeutic agents

(2013) IGOR P. POGRIBNY et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

Iron Chelation in the Treatment of Cancer: A New Role for Deferasirox?

(2013) Matthew R. Bedford et al.   JOURNAL OF CLINICAL PHARMACOLOGY

Iron chelation therapy in myelodysplastic syndromes: where do we stand?

(2013) Mhairi Mitchell et al.   Expert Review of Hematology

Intestinal Iron Homeostasis and Colon Tumorigenesis

(2013) Xiang Xue et al.   Nutrients

Iron Chelators with Topoisomerase-Inhibitory Activity and Their Anticancer Applications

(2012) V. Ashutosh Rao   ANTIOXIDANTS & REDOX SIGNALING

Hypoxia-Inducible Factor-2  Activation Promotes Colorectal Cancer Progression by Dysregulating Iron Homeostasis

(2012) X. Xue et al.   CANCER RESEARCH

Lipocalin 2 is a novel regulator of angiogenesis in human breast cancer

(2012) Jiang Yang et al.   FASEB JOURNAL

Ferritin as an independent mortality predictor in patients with pancreas cancer. Results of a pilot study

(2012) Marta Kalousová et al.   TUMOR BIOLOGY

Essential but toxic: Controlling the flux of iron in the body

(2011) Gregory J Anderson et al.   CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY

Role of ferritin alterations in human breast cancer cells

(2010) Svitlana I. Shpyleva et al.   BREAST CANCER RESEARCH AND TREATMENT

The hazards of iron loading

(2010) Eugene D. Weinberg   Metallomics

Ferroportin and Iron Regulation in Breast Cancer Progression and Prognosis

(2010) Z. K. Pinnix et al.   Science Translational Medicine

Transferrin receptor (CD71) is a marker of poor prognosis in breast cancer and can predict response to tamoxifen

(2009) Hany Onsy Habashy et al.   BREAST CANCER RESEARCH AND TREATMENT

HFE C282Y homozygotes are at increased risk of breast and colorectal cancer

(2009) Nicholas J. Osborne et al.   HEPATOLOGY

Dietary and stored iron as predictors of breast cancer risk: A nested case-control study in Shanghai

(2009) Amber B. Moore et al.   INTERNATIONAL JOURNAL OF CANCER

Lipocalin 2 promotes breast cancer progression

(2009) J. Yang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Transferrin Receptor Modulates Hfe-Dependent Regulation of Hepcidin Expression

(2008) Paul J. Schmidt et al.   Cell Metabolism

The Serine Protease Matriptase-2 (TMPRSS6) Inhibits Hepcidin Activation by Cleaving Membrane Hemojuvelin

(2008) Laura Silvestri et al.   Cell Metabolism

Does iron have a role in breast cancer?

(2008) Xi Huang   LANCET ONCOLOGY

Flow cytometry measurement of the labile iron pool in human hematopoietic cells

(2007) Eugenia Prus et al.   CYTOMETRY PART A