Physical Interaction between MYCN Oncogene and Polycomb Repressive Complex 2 (PRC2) in Neuroblastoma

EZH2 Mediates Epigenetic Silencing of Neuroblastoma Suppressor Genes CASZ1, CLU, RUNX3, and NGFR

(2011) C. Wang et al.   CANCER RESEARCH

A SP1/MIZ1/MYCN Repression Complex Recruits HDAC1 at theTRKAandp75NTRPromoters and Affects Neuroblastoma Malignancy by Inhibiting the Cell Response to NGF

(2010) Nunzio Iraci et al.   CANCER RESEARCH

The Myc-miR-17 92 Axis Blunts TGF  Signaling and Production of Multiple TGF -Dependent Antiangiogenic Factors

(2010) M. Dews et al.   CANCER RESEARCH

The polycomb group protein BMI1 is a transcriptional target of HDAC inhibitors

(2010) Prashant V. Bommi et al.   CELL CYCLE

Clinical Studies of Histone Deacetylase Inhibitors

(2009) H. M. Prince et al.   CLINICAL CANCER RESEARCH

Clusterin, a Haploinsufficient Tumor Suppressor Gene in Neuroblastomas

(2009) Olesya Chayka et al.   JNCI-Journal of the National Cancer Institute

The Legacy of Cancer Therapy in Children

(2009) Elizabeth Fox et al.   JNCI-Journal of the National Cancer Institute

Gene Regulation and Epigenetic Remodeling in Murine Embryonic Stem Cells by c-Myc

(2009) Chin-Hsing Lin et al.   PLoS One

ODC1 Is a Critical Determinant of MYCN Oncogenesis and a Therapeutic Target in Neuroblastoma

(2008) M. D. Hogarty et al.   CANCER RESEARCH

Histone Deacetylase Inhibitor Panobinostat Induces Clinical Responses with Associated Alterations in Gene Expression Profiles in Cutaneous T-Cell Lymphoma

(2008) L. Ellis et al.   CLINICAL CANCER RESEARCH

Myc's broad reach

(2008) M. Eilers et al.   GENES & DEVELOPMENT

Antagomir-17-5p Abolishes the Growth of Therapy-Resistant Neuroblastoma through p21 and BIM

(2008) Laura Fontana et al.   PLoS One

Bivalent domains enforce transcriptional memory of DNA methylated genes in cancer cells

(2008) J. Rodriguez et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MYCN regulates oncogenic MicroRNAs in neuroblastoma

(2007) Johannes H. Schulte et al.   INTERNATIONAL JOURNAL OF CANCER