General Method for Ni-Catalyzed C–N Cross-Couplings of (Hetero)Aryl Chlorides with Anilines and Aliphatic Amines under Homogeneous Conditions Using a Dual-Base Strategy

Emerging reaction technologies in pharmaceutical development: Challenges and opportunities in electrochemistry, photochemistry, and biocatalysis

(2023) Benjamin Cohen et al.   CHEMICAL ENGINEERING RESEARCH & DESIGN

Room-Temperature Cu-Catalyzed Amination of Aryl Bromides Enabled by DFT-Guided Ligand Design

(2023) Seoung-Tae Kim et al.   Journal of the American Chemical Society

Escape from Palladium: Nickel-Catalyzed Catellani Annulation

(2023) Jingfeng Huo et al.   Journal of the American Chemical Society

Collaboration as a Key to Advance Capabilities for Earth-Abundant Metal Catalysis

(2023) Paul J. Chirik et al.   Organic Process Research & Development

Mapping Dual‐Base‐Enabled Nickel‐Catalyzed Aryl Amidations: Application in the Synthesis of 4‐Quinolones

(2022) Ryan T. McGuire et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Development of a Commercial Process for Deucravacitinib, a Deuterated API for TYK2 Inhibition

(2022) Daniel S. Treitler et al.   ORGANIC PROCESS RESEARCH & DEVELOPMENT

Nickel-Catalyzed C–N Cross-Coupling of 4-Chloro-1,8-naphthalimides and Bulky, Primary Alkylamines at Room Temperature

(2022) Joseph P. Tassone et al.   JOURNAL OF ORGANIC CHEMISTRY

Cu-Mediated Ullmann-Type Cross-Coupling and Industrial Applications in Route Design, Process Development, and Scale-up of Pharmaceutical and Agrochemical Processes

(2022) Qiang Yang et al.   ORGANIC PROCESS RESEARCH & DEVELOPMENT

Structure–Reactivity Relationships of Buchwald-Type Phosphines in Nickel-Catalyzed Cross-Couplings

(2022) Samuel H. Newman-Stonebraker et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Ni(COD)(DQ): An Air-Stable 18-Electron Ni(0)-Olefin Precatalyst

(2020) Van Tran et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

The Quest for the Ideal Base: Rational Design of a Nickel Precatalyst Enables Mild, Homogeneous C–N Cross-Coupling

(2020) Richard Y. Liu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Ni(4-tBustb)3: A Robust 16-Electron Ni(0) Olefin Complex for Catalysis

(2020) Lukas Nattmann et al.   ORGANOMETALLICS

Using nature’s blueprint to expand catalysis with Earth-abundant metals

(2020) R. Morris Bullock et al.   SCIENCE

Nickel‐Catalyzed N‐Arylation of Fluoroalkylamines

(2020) Ryan McGuire et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Nickel-Catalyzed N-Arylation of Amides with (Hetero)aryl Electrophiles by Using a DBU/NaTFA Dual-Base System

(2020) Mark Stradiotto et al.   SYNLETT

PhPAd-DalPhos: Ligand-Enabled, Nickel-Catalyzed Cross-Coupling of (Hetero)aryl Electrophiles with Bulky Primary Alkylamines

(2019) Joseph Tassone et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Electrochemically Driven, Ni-Catalyzed Aryl Amination: Scope, Mechanism, and Applications

(2019) Yu Kawamata et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

PAd2-DalPhos Enables the Nickel-Catalyzed C-N Cross-Coupling of Primary Heteroarylamines and (Hetero)aryl Chlorides

(2019) Jillian Clark et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Palladium-Catalyzed Amidation and Amination of (Hetero)aryl Chlorides under Homogeneous Conditions Enabled by a Soluble DBU/NaTFA Dual-Base System

(2019) Gregory L. Beutner et al.   ORGANIC PROCESS RESEARCH & DEVELOPMENT

The 25th Anniversary of the Buchwald–Hartwig Amination: Development, Applications, and Outlook

(2019) Paola A. Forero-Cortés et al.   ORGANIC PROCESS RESEARCH & DEVELOPMENT

Nickel-Catalyzed C–N Cross-Coupling of Ammonia, (Hetero)anilines, and Indoles with Activated (Hetero)aryl Chlorides Enabled by Ligand Design

(2019) Ryan T. McGuire et al.   ACS Catalysis

Bisphosphines: A Prominent Ancillary Ligand Class for Application in Nickel-Catalyzed C–N Cross-Coupling

(2018) Christopher M. Lavoie et al.   ACS Catalysis

Palladium-Catalyzed Cross-Coupling Reactions: A Powerful Tool for the Synthesis of Agrochemicals

(2018) Ponnam Devendar et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Ni-Catalyzed Amination Reactions: An Overview

(2016) Mario Marín et al.   CHEMICAL RECORD

Applications of Palladium-Catalyzed C–N Cross-Coupling Reactions

(2016) Paula Ruiz-Castillo et al.   CHEMICAL REVIEWS

A Comparative Reactivity Survey of Some Prominent Bisphosphine Nickel(II) Precatalysts in C–N Cross-Coupling

(2016) Jillian S. K. Clark et al.   ORGANOMETALLICS

Aryl amination using ligand-free Ni(II) salts and photoredox catalysis

(2016) Emily B. Corcoran et al.   SCIENCE

Challenging nickel-catalysed amine arylations enabled by tailored ancillary ligand design

(2016) Christopher M. Lavoie et al.   Nature Communications

Nickel-Catalyzed Monoarylation of Ammonia

(2015) Andrey Borzenko et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A Modular, Air-Stable Nickel Precatalyst

(2015) Jason D. Shields et al.   ORGANIC LETTERS

Development of an Air-Stable, Broadly Applicable Nickel Source for Nickel-Catalyzed Cross-Coupling

(2015) Javier Magano et al.   ACS Catalysis

A robustness screen for the rapid assessment of chemical reactions

(2013) Karl D. Collins et al.   Nature Chemistry

Development of an Air-Stable Nickel Precatalyst for the Amination of Aryl Chlorides, Sulfamates, Mesylates, and Triflates

(2013) Nathaniel H. Park et al.   ORGANIC LETTERS

Room-temperature nickel-catalyzed amination of heteroaryl/aryl chlorides with Ni(II)–(σ-Aryl) complex as precatalyst

(2011) Xin-Heng Fan et al.   JOURNAL OF ORGANOMETALLIC CHEMISTRY

Nickel-catalyzed cross-coupling of diarylamines with haloarenes

(2009) Cai-Yan Gao et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

The Development of Versatile Methods for Palladium-Catalyzed Coupling Reactions of Aryl Electrophiles through the Use of P(t-Bu)3and PCy3as Ligands

(2008) Gregory C. Fu   ACCOUNTS OF CHEMICAL RESEARCH

Nickel-Catalyzed Amination of Aryl Tosylates

(2008) Cai-Yan Gao et al.   JOURNAL OF ORGANIC CHEMISTRY