Glutamine stimulates the S6K/4E-BP branch of insulin signalling pathway to mitigate human poly(Q) disorders in Drosophila disease models

Glipizide ameliorates human poly(Q) mediated neurotoxicity by upregulating insulin signalling in Drosophila disease models

(2023) Shweta Tandon et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The S6k/4E-BP mediated growth promoting sub-pathway of insulin signalling cascade is essential to restrict pathogenesis of poly(Q) disorders in Drosophila

(2021) Shweta Tandon et al.   LIFE SCIENCES

Polyglutamine diseases

(2021) Emma L. Bunting et al.   CURRENT OPINION IN NEUROBIOLOGY

Insulin-like growth factor 1 signaling in motor neuron and polyglutamine diseases: From molecular pathogenesis to therapeutic perspectives

(2020) Maria Pennuto et al.   FRONTIERS IN NEUROENDOCRINOLOGY

Insulin signaling pathway and related molecules: Role in neurodegeneration and Alzheimer's disease

(2020) Ansab Akhtar et al.   NEUROCHEMISTRY INTERNATIONAL

Insulin-like growth factor 2 (IGF2) protects against Huntington’s disease through the extracellular disposal of protein aggregates

(2020) Paula García-Huerta et al.   ACTA NEUROPATHOLOGICA

Compromised IGF signaling causes caspase-6 activation in Huntington disease

(2020) Niels Henning Skotte et al.   EXPERIMENTAL NEUROLOGY

A comprehensive insight into the effect of glutamine supplementation on metabolic variables in diabetes mellitus: a systematic review

(2020) Hamed Jafari-Vayghan et al.   Nutrition & Metabolism

L-glutamine protects mouse brain from ischemic injury via up-regulating heat shock protein 70

(2019) Long-Long Luo et al.   CNS Neuroscience & Therapeutics

Anabolic SIRT4 exerts retrograde control over TORC1 signalling by glutamine sparing in the mitochondria

(2019) Eisha Shaw et al.   MOLECULAR AND CELLULAR BIOLOGY

L-glutamine for sickle cell anemia: more questions than answers

(2018) Charles T. Quinn   BLOOD

Polyglutamine expansion diseases: More than simple repeats

(2018) Alexandra Silva et al.   JOURNAL OF STRUCTURAL BIOLOGY

Tissue-Specific Upregulation of Drosophila Insulin Receptor (InR) Mitigates Poly(Q)-Mediated Neurotoxicity by Restoration of Cellular Transcription Machinery

(2018) Kritika Raj et al.   MOLECULAR NEUROBIOLOGY

Polyglutamine Repeats in Neurodegenerative Diseases

(2018) Andrew P. Lieberman et al.   Annual Review of Pathology-Mechanisms of Disease

Glutamine: Metabolism and Immune Function, Supplementation and Clinical Translation

(2018) Vinicius Cruzat et al.   Nutrients

The impact of glutamine supplementation on the symptoms of ataxia-telangiectasia: a preclinical assessment

(2016) Jianmin Chen et al.   Molecular Neurodegeneration

Regional tumour glutamine supply affects chromatin and cell identity

(2016) Jonas W. Højfeldt et al.   NATURE CELL BIOLOGY

Prolonging the survival of Tsc2 conditional knockout mice by glutamine supplementation

(2015) Natalia S. Rozas et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Differential regulation of mTORC1 by leucine and glutamine

(2015) J. L. Jewell et al.   SCIENCE

Evaluation of acridine orange, LysoTracker Red, and quinacrine as fluorescent probes for long-term tracking of acidic vesicles

(2014) Agnieszka Pierzyńska-Mach et al.   CYTOMETRY PART A

Making new contacts: the mTOR network in metabolism and signalling crosstalk

(2014) Mitsugu Shimobayashi et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Glutamine Acts as a Neuroprotectant against DNA Damage, Beta-Amyloid and H2O2-Induced Stress

(2012) Jianmin Chen et al.   PLoS One

Huntingtin Aggregation Kinetics and Their Pathological Role in a Drosophila Huntington’s Disease Model

(2011) Kurt R. Weiss et al.   GENETICS

Glutamine as an Immunonutrient

(2011) Hyeyoung Kim   YONSEI MEDICAL JOURNAL

Glutamine, arginine, and leucine signaling in the intestine

(2009) J. Marc Rhoads et al.   AMINO ACIDS

Evaluation of a novel food composition database that includes glutamine and other amino acids derived from gene sequencing data

(2009) C M Lenders et al.   EUROPEAN JOURNAL OF CLINICAL NUTRITION

Glutamine: role in critical illness and ongoing clinical trials

(2008) Paul E Wischmeyer   CURRENT OPINION IN GASTROENTEROLOGY