Isoquercetin Ameliorates Cerebral Impairment in Focal Ischemia Through Anti-Oxidative, Anti-Inflammatory, and Anti-Apoptotic Effects in Primary Culture of Rat Hippocampal Neurons and Hippocampal CA1 Region of Rats

Effect of Mixed Flavonoids, n-3 Fatty Acids, and Vitamin C on Oxidative Stress and Antioxidant Capacity before and after Intense Cycling

(2016) Steven R. McAnulty et al.   INTERNATIONAL JOURNAL OF SPORT NUTRITION AND EXERCISE METABOLISM

Who does it first? The uptake of medical innovations in the performance of thrombolysis on ischemic stroke patients in Germany: a study based on hospital quality data

(2015) Nadine Scholten et al.   Implementation Science

Neuroprotective Effect of Prenylated Arylbenzofuran and Flavonoids fromMorus albaFruits on Glutamate-Induced Oxidative Injury in HT22 Hippocampal Cells

(2015) Kyeong-Hwa Seo et al.   JOURNAL OF MEDICINAL FOOD

Endogenous and exogenous mediators of quercetin bioavailability

(2015) Yi Guo et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Neuroprotective effect of nobiletin on cerebral ischemia–reperfusion injury in transient middle cerebral artery-occluded rats

(2014) Nodoka Yasuda et al.   BRAIN RESEARCH

Detecting brain injury in neonatal hypoxic ischemic encephalopathy: Closing the gap between experimental and clinical research

(2014) James D.S. Aridas et al.   EXPERIMENTAL NEUROLOGY

Ligustilide ameliorates neuroinflammation and brain injury in focal cerebral ischemia/reperfusion rats: involvement of inhibition of TLR4/peroxiredoxin 6 signaling

(2014) Xi Kuang et al.   FREE RADICAL BIOLOGY AND MEDICINE

Hydrogen sulfide protects blood-brain barrier integrity following cerebral ischemia

(2014) Yali Wang et al.   JOURNAL OF NEUROCHEMISTRY

Neuroprotective effects of bilobalide on cerebral ischemia and reperfusion injury are associated with inhibition of pro-inflammatory mediator production and down-regulation of JNK1/2 and p38 MAPK activation

(2014) Mingjin Jiang et al.   Journal of Neuroinflammation

New Insights Into the Pharmacological Potential of Plant Flavonoids in the Catecholamine System

(2014) Nobuyuki Yanagihara et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

Activation of GABAB Receptors Ameliorates Cognitive Impairment via Restoring the Balance of HCN1/HCN2 Surface Expression in the Hippocampal CA1 Area in Rats With Chronic Cerebral Hypoperfusion

(2014) Chang-jun Li et al.   MOLECULAR NEUROBIOLOGY

A novel multi-target ligand (JM-20) protects mitochondrial integrity, inhibits brain excitatory amino acid release and reduces cerebral ischemia injury in vitro and in vivo

(2014) Yanier Nuñez-Figueredo et al.   NEUROPHARMACOLOGY

Metabotropic glutamate receptor 5 modulates calcium oscillation and innate immune response induced by lipopolysaccharide in microglial cell

(2014) F. Liu et al.   NEUROSCIENCE

Sirt1 Mediates Hyperbaric Oxygen Preconditioning-Induced Ischemic Tolerance in Rat Brain

(2013) Wenjun Yan et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Evidence that collaboration between HIF-1α and Notch-1 promotes neuronal cell death in ischemic stroke

(2013) Yi-Lin Cheng et al.   NEUROBIOLOGY OF DISEASE

Isoquercetin protects cortical neurons from oxygen–glucose deprivation–reperfusion induced injury via suppression of TLR4–NF-кB signal pathway

(2013) Cai-Ping Wang et al.   NEUROCHEMISTRY INTERNATIONAL

Mitigation of Murine Focal Cerebral Ischemia by the Hypocretin/Orexin System is Associated With Reduced Inflammation

(2013) Xiaoxing Xiong et al.   STROKE

Flavonoid intake and cardiovascular disease mortality in a prospective cohort of US adults

(2012) Marjorie L McCullough et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Mechanisms of Neuronal Damage and Neuroprotection Underlying Ischemia/Reperfusion Injury after Physical Exercise

(2012) Yuchuan Ding   CURRENT DRUG TARGETS

Glibenclamide Enhances Neurogenesis and Improves Long-Term Functional Recovery after Transient Focal Cerebral Ischemia

(2012) Francisco J Ortega et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Regulation of enhanced cerebrovascular expression of proinflammatory mediators in experimental subarachnoid hemorrhage via the mitogen-activated protein kinase kinase/extracellular signal-regulated kinase pathway

(2012) Aida Maddahi et al.   Journal of Neuroinflammation

Mammalian MAPK Signal Transduction Pathways Activated by Stress and Inflammation: A 10-Year Update

(2012) John M. Kyriakis et al.   PHYSIOLOGICAL REVIEWS

Alternatively-Spliced Extra Domain A of Fibronectin Promotes Acute Inflammation and Brain Injury After Cerebral Ischemia in Mice

(2012) Mohammad Moshahid Khan et al.   STROKE

Activation and Function of the MAPKs and Their Substrates, the MAPK-Activated Protein Kinases

(2011) M. Cargnello et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

The immunology of stroke: from mechanisms to translation

(2011) Costantino Iadecola et al.   NATURE MEDICINE

Lutein enhances survival and reduces neuronal damage in a mouse model of ischemic stroke

(2011) Suk-Yee Li et al.   NEUROBIOLOGY OF DISEASE

Total Antioxidant Capacity of Diet and Risk of Stroke

(2011) Susanne Rautiainen et al.   STROKE

Oxidative Stress in Ischemic Brain Damage: Mechanisms of Cell Death and Potential Molecular Targets for Neuroprotection

(2010) Hai Chen et al.   ANTIOXIDANTS & REDOX SIGNALING

Neuroprotective and neurotrophic curcuminoids to treat stroke: a translational perspective

(2010) Paul A Lapchak   EXPERT OPINION ON INVESTIGATIONAL DRUGS

Cerebral ischemia induces micro vascular pro-inflammatory cytokine expression via the MEK/ERK pathway

(2010) Aida Maddahi et al.   Journal of Neuroinflammation

Treatment of cerebral ischemia by disrupting ischemia-induced interaction of nNOS with PSD-95

(2010) Li Zhou et al.   NATURE MEDICINE

Magnetic resonance biomarkers of neuroprotective effects in infants with hypoxic ischemic encephalopathy

(2010) Denis Azzopardi et al.   Seminars in Fetal & Neonatal Medicine

Validation of housekeeping genes for quantitative real-time PCR in in-vivo and in-vitro models of cerebral ischaemia

(2009) Carme Gubern et al.   BMC MOLECULAR BIOLOGY

Non-receptor tyrosine kinase Src is required for ischemia-stimulated neuronal cell proliferation via Raf/ERK/CREB activation in the dentate gyrus

(2009) He-Ping Tian et al.   BMC NEUROSCIENCE

JNK inhibition and inflammation after cerebral ischemia

(2009) Corinne Benakis et al.   BRAIN BEHAVIOR AND IMMUNITY

Neuroinflammation and Neuroprotective Strategies in Acute Ischaemic Stroke - from bench to bedside

(2009) Imtiaz Shah et al.   CURRENT MOLECULAR MEDICINE

Inflammatory mechanisms in ischemic stroke: therapeutic approaches

(2009) Shaheen E Lakhan et al.   Journal of Translational Medicine

Effects of Quercetin and EGCG on Mitochondrial Biogenesis and Immunity

(2009) DAVID C. NIEMAN et al.   MEDICINE AND SCIENCE IN SPORTS AND EXERCISE

Estradiol-17β protects against hypoxia-induced hepatocyte injury through ER-mediated upregulation of Bcl-2 as well as ER-independent antioxidant effects

(2008) Min Young Lee et al.   CELL RESEARCH

Anti-inflammatory treatment with the p38 mitogen-activated protein kinase inhibitor SB239063 is neuroprotective, decreases the number of activated microglia and facilitates neurogenesis in oxygen–glucose-deprived hippocampal slice cultures

(2008) Maria Strassburger et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Dual roles of the MAPK/ERK1/2 cell signaling pathway after stroke

(2008) Nik Sawe et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Cerebral ischemia: Models, methods and outcomes

(2007) Konstantin-Alexander Hossmann   NEUROPHARMACOLOGY