Atorvastatin Protects from Aβ1–40-Induced Cell Damage and Depressive-Like Behavior via ProBDNF Cleavage

Guanosine Prevents Anhedonic-Like Behavior and Impairment in Hippocampal Glutamate Transport Following Amyloid-β1–40 Administration in Mice

(2016) Débora Lanznaster et al.   MOLECULAR NEUROBIOLOGY

Atorvastatin Prevents Cognitive Deficits Induced by Intracerebroventricular Amyloid-β1–40 Administration in Mice: Involvement of Glutamatergic and Antioxidant Systems

(2015) Wagner C. Martins et al.   NEUROTOXICITY RESEARCH

Tissue-type plasminogen activator is a neuroprotectant in the central nervous system

(2015) Manuel Yepes   Frontiers in Cellular Neuroscience

Dysregulation of TrkB Receptors and BDNF Function by Amyloid-β Peptide is Mediated by Calpain

(2014) André Jerónimo-Santos et al.   CEREBRAL CORTEX

Sex-specific disruptions in spatial memory and anhedonia in a “two hit” rat model correspond with alterations in hippocampal brain-derived neurotrophic factor expression and signaling

(2014) Rachel A. Hill et al.   HIPPOCAMPUS

A Local Glutamate-Glutamine Cycle Sustains Synaptic Excitatory Transmitter Release

(2014) Hiroaki Tani et al.   NEURON

Non-hypotensive dose of telmisartan and nimodipine produced synergistic neuroprotective effect in cerebral ischemic model by attenuating brain cytokine levels

(2014) A. Justin et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Atorvastatin evokes a serotonergic system-dependent antidepressant-like effect in mice

(2014) Fabiana K. Ludka et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Efficacy of Lovastatin on Learning and Memory Deficits Caused by Chronic Intermittent Hypoxia-Hypercapnia: Through Regulation of NR2B-Containing NMDA Receptor-ERK Pathway

(2014) Xin-long Huo et al.   PLoS One

Cognitive, motor and tyrosine hydroxylase temporal impairment in a model of parkinsonism induced by reserpine

(2013) José R. Santos et al.   BEHAVIOURAL BRAIN RESEARCH

Neuropeptide Y (NPY) prevents depressive-like behavior, spatial memory deficits and oxidative stress following amyloid-β (Aβ1–40) administration in mice

(2013) Vanessa V. dos Santos et al.   BEHAVIOURAL BRAIN RESEARCH

Statins more than cholesterol lowering agents in Alzheimer disease: Their pleiotropic functions as potential therapeutic targets

(2013) Eugenio Barone et al.   BIOCHEMICAL PHARMACOLOGY

Effects of corticosterone and amyloid-beta on proteins essential for synaptic function: Implications for depression and Alzheimer's disease

(2013) Suthicha Wuwongse et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Guanosine controls inflammatory pathways to afford neuroprotection of hippocampal slices under oxygen and glucose deprivation conditions

(2013) Tharine Dal-Cim et al.   JOURNAL OF NEUROCHEMISTRY

Deregulation of excitatory neurotransmission underlying synapse failure in Alzheimer's disease

(2013) Andrea C. Paula-Lima et al.   JOURNAL OF NEUROCHEMISTRY

p11 and its role in depression and therapeutic responses to antidepressants

(2013) Per Svenningsson et al.   NATURE REVIEWS NEUROSCIENCE

Atorvastatin prevents cell damage via modulation of oxidative stress, glutamate uptake and glutamine synthetase activity in hippocampal slices subjected to oxygen/glucose deprivation

(2013) Samuel Vandresen-Filho et al.   NEUROCHEMISTRY INTERNATIONAL

Neuroprotective and procognitive effects of sertraline: In vitro and in vivo studies

(2013) Michal Taler et al.   NEUROSCIENCE LETTERS

Acute atorvastatin treatment exerts antidepressant-like effect in mice via the l-arginine–nitric oxide–cyclic guanosine monophosphate pathway and increases BDNF levels

(2012) Fabiana K. Ludka et al.   EUROPEAN NEUROPSYCHOPHARMACOLOGY

Amyloid-β oligomers link depressive-like behavior and cognitive deficits in mice

(2012) J H Ledo et al.   MOLECULAR PSYCHIATRY

Atorvastatin and pitavastatin reduce senile plaques and inflammatory responses in a mouse model of Alzheimer’s disease

(2012) Tomoko Kurata et al.   NEUROLOGICAL RESEARCH

Brain Derived Neurotrophic Factor: A novel neurotrophin involved in psychiatric and neurological disorders

(2012) Sivasankaran Balaratnasingam et al.   PHARMACOLOGY & THERAPEUTICS

Desipramine Protects Neuronal Cell Death and Induces Heme Oxygenase-1 Expression in Mes23.5 Dopaminergic Neurons

(2012) Hsiao-Yun Lin et al.   PLoS One

Heterogeneity of elderly depression: Increased risk of Alzheimer's disease and Aβ protein metabolism

(2012) Yuki Namekawa et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Biliverdin reductase-A: a novel drug target for atorvastatin in a dog pre-clinical model of Alzheimer disease

(2011) Eugenio Barone et al.   JOURNAL OF NEUROCHEMISTRY

Atorvastatin prevents hippocampal cell death, neuroinflammation and oxidative stress following amyloid-β1–40 administration in mice: Evidence for dissociation between cognitive deficits and neuronal damage

(2010) Tetsadê C.B. Piermartiri et al.   EXPERIMENTAL NEUROLOGY

N-Methyl-d-aspartate receptors are required for synaptic targeting of Alzheimer’s toxic amyloid-β peptide oligomers

(2010) Helena Decker et al.   JOURNAL OF NEUROCHEMISTRY

Atorvastatin Prevents Hippocampal Cell Death due to Quinolinic Acid-Induced Seizures in Mice by Increasing Akt Phosphorylation and Glutamate Uptake

(2009) Tetsadê C. B. Piermartiri et al.   NEUROTOXICITY RESEARCH

Involvement of hippocampal serotonin and neuropeptide Y in depression induced by chronic unpredicted mild stress

(2008) D.D. Luo et al.   BRAIN RESEARCH BULLETIN