Dysregulation of TrkB Receptors and BDNF Function by Amyloid-β Peptide is Mediated by Calpain

Predominant loss of glutamatergic terminal markers in a β-amyloid peptide model of Alzheimer's disease

(2013) Paula M. Canas et al.   NEUROPHARMACOLOGY

Calpain Inhibitor A-705253 Mitigates Alzheimer's Disease–Like Pathology and Cognitive Decline in Aged 3xTgAD Mice

(2012) Rodrigo Medeiros et al.   AMERICAN JOURNAL OF PATHOLOGY

Excitotoxicity Downregulates TrkB.FL Signaling and Upregulates the Neuroprotective Truncated TrkB Receptors in Cultured Hippocampal and Striatal Neurons

(2012) J. R. Gomes et al.   JOURNAL OF NEUROSCIENCE

Amyloid beta selectively modulates neuronal TrkB alternative transcript expression with implications for Alzheimer's disease

(2012) J. Wong et al.   NEUROSCIENCE

Imbalance of neurotrophin receptor isoforms TrkB-FL/TrkB-T1 induces neuronal death in excitotoxicity

(2012) Ó G Vidaurre et al.   Cell Death & Disease

Age-related changes of glycine receptor at the rat hippocampus: from the embryo to the adult

(2011) Rita I. Aroeira et al.   JOURNAL OF NEUROCHEMISTRY

The amyloid cascade hypothesis for Alzheimer's disease: an appraisal for the development of therapeutics

(2011) Eric Karran et al.   NATURE REVIEWS DRUG DISCOVERY

Enhancement of LTP in Aged Rats is Dependent on Endogenous BDNF

(2011) Maria J Diógenes et al.   NEUROPSYCHOPHARMACOLOGY

7,8-Dihydroxyflavone, a Small-Molecule TrkB Agonist, Reverses Memory Deficits and BACE1 Elevation in a Mouse Model of Alzheimer's Disease

(2011) Latha Devi et al.   NEUROPSYCHOPHARMACOLOGY

Calpain inhibition prevents amyloid-β-induced neurodegeneration and associated behavioral dysfunction in rats

(2010) Ivica Granic et al.   NEUROPHARMACOLOGY

Regulation of Hippocampal Cannabinoid CB1 Receptor Actions by Adenosine A1 Receptors and Chronic Caffeine Administration: Implications for the Effects of Δ9-Tetrahydrocannabinol on Spatial Memory

(2010) Vasco C Sousa et al.   NEUROPSYCHOPHARMACOLOGY

Stimulus pattern dependence of the Alzheimer's disease amyloid-β 42 peptide's inhibition of long term potentiation in mouse hippocampal slices

(2009) Jeffrey P. Smith et al.   BRAIN RESEARCH

Proteolytic cleavages give receptor tyrosine kinases the gift of ubiquity

(2009) F Ancot et al.   ONCOGENE

Neural stem cells improve cognition via BDNF in a transgenic model of Alzheimer disease

(2009) M. Blurton-Jones et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Inhibition of calpains improves memory and synaptic transmission in a mouse model of Alzheimer disease

(2008) Fabrizio Trinchese et al.   JOURNAL OF CLINICAL INVESTIGATION

Protective effect of BDNF against beta-amyloid induced neurotoxicity in vitro and in vivo in rats

(2008) S. Arancibia et al.   NEUROBIOLOGY OF DISEASE

Enhancement of long-term potentiation by brain-derived neurotrophic factor requires adenosine A2A receptor activation by endogenous adenosine

(2008) B.M. Fontinha et al.   NEUROPHARMACOLOGY

Role of calpain and caspase in β-amyloid-induced cell death in rat primary septal cultured neurons

(2007) Z. Wei et al.   NEUROPHARMACOLOGY