Tissue-type plasminogen activator is a neuroprotectant in the central nervous system

Tissue-type plasminogen activator is an extracellular mediator of Purkinje cell damage and altered gait

(2013) Elisa J. Cops et al.   EXPERIMENTAL NEUROLOGY

tPA Regulates Neurite Outgrowth by Phosphorylation of LRP5/6 in Neural Progenitor Cells

(2013) Sung Hoon Lee et al.   MOLECULAR NEUROBIOLOGY

Tissue-type plasminogen activator mediates neuroglial coupling in the central nervous system

(2013) J. An et al.   NEUROSCIENCE

Tissue plasminogen activator regulates Purkinje neuron development and survival

(2013) J. Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Tissue-Type Plasminogen Activator Regulates the Neuronal Uptake of Glucose in the Ischemic Brain

(2012) F. Wu et al.   JOURNAL OF NEUROSCIENCE

Tissue-type plasminogen activator protects neurons from excitotoxin-induced cell death via activation of the ERK1/2–CREB–ATF3 signaling pathway

(2012) Fang Wu et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Tissue-Type Plasminogen Activator has a Neuroprotective Effect in the Ischemic Brain Mediated by Neuronal TNF-α

(2011) Woldeab B Haile et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Subacute intranasal administration of tissue plasminogen activator increases functional recovery and axonal remodeling after stroke in rats

(2011) Zhongwu Liu et al.   NEUROBIOLOGY OF DISEASE

Endogenous Tissue Plasminogen Activator Mediates Bone Marrow Stromal Cell-Induced Neurite Remodeling After Stroke in Mice

(2011) Li Hong Shen et al.   STROKE

Neuroserpin Protects Neurons from Ischemia-Induced Plasmin-Mediated Cell Death Independently of Tissue-Type Plasminogen Activator Inhibition

(2010) Jialing Wu et al.   AMERICAN JOURNAL OF PATHOLOGY

Human Recombinant Tissue-Plasminogen Activator (Alteplase): Why Not Use the ‘Human’ Dose for Stroke Studies in Rats?

(2010) Benoît Haelewyn et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Tissue-type plasminogen activator is a neuroprotectant in the mouse hippocampus

(2010) Ramiro Echeverry et al.   JOURNAL OF CLINICAL INVESTIGATION

Synaptic versus extrasynaptic NMDA receptor signalling: implications for neurodegenerative disorders

(2010) Giles E. Hardingham et al.   NATURE REVIEWS NEUROSCIENCE

Publication Bias in Reports of Animal Stroke Studies Leads to Major Overstatement of Efficacy

(2010) Emily S. Sena et al.   PLOS BIOLOGY

Hypoxia Inducible Factor 1 as a Therapeutic Target in Ischemic Stroke

(2009) Honglian Shi   CURRENT MEDICINAL CHEMISTRY

The Serine Protease Plasmin Cleaves the Amino-terminal Domain of the NR2A Subunit to Relieve Zinc Inhibition of theN-Methyl-d-aspartate Receptors

(2009) Hongjie Yuan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Thrombolytic Toxicity: Blood Brain Barrier Disruption in Human Ischemic Stroke

(2008) Chelsea S. Kidwell et al.   CEREBROVASCULAR DISEASES

Tissue-type plasminogen activator requires a co-receptor to enhance NMDA receptor function

(2008) Andre L. Samson et al.   JOURNAL OF NEUROCHEMISTRY