Guanosine controls inflammatory pathways to afford neuroprotection of hippocampal slices under oxygen and glucose deprivation conditions

G protein-coupled receptor oligomerization and brain integration: Focus on adenosinergic transmission

(2012) Francisco Ciruela et al.   BRAIN RESEARCH

Adenosine A2A receptors modulate glutamate uptake in cultured astrocytes and gliosomes

(2012) Marco Matos et al.   GLIA

Purine nucleosides: endogenous neuroprotectants in hypoxic brain

(2012) Bettina Thauerer et al.   JOURNAL OF NEUROCHEMISTRY

Guanosine protects human neuroblastoma SH-SY5Y cells against mitochondrial oxidative stress by inducing heme oxigenase-1 via PI3K/Akt/GSK-3β pathway

(2012) Tharine Dal-Cim et al.   NEUROCHEMISTRY INTERNATIONAL

Isoorientin induces apoptosis through mitochondrial dysfunction and inhibition of PI3K/Akt signaling pathway in HepG2 cancer cells

(2012) Li Yuan et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Systemic administration of guanosine promotes functional and histological improvement following an ischemic stroke in rats

(2011) Michel P. Rathbone et al.   BRAIN RESEARCH

Evidence for the Existence of a Specific G Protein-Coupled Receptor Activated by Guanosine

(2011) Rosaria Volpini et al.   ChemMedChem

The Role of Extracellular Adenosine in Chemical Neurotransmission in the Hippocampus and Basal Ganglia: Pharmacological and Clinical Aspects

(2011) Beata Sperlagh et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Modulation of GABA Transport by Adenosine A1R-A2AR Heteromers, Which Are Coupled to Both Gs- and Gi/o-Proteins

(2011) S. Cristovao-Ferreira et al.   JOURNAL OF NEUROSCIENCE

Neuroprotective effect of guanosine against glutamate-induced cell death in rat hippocampal slices is mediated by the phosphatidylinositol-3 kinase/Akt/ glycogen synthase kinase 3β pathway activation and inducible nitric oxide synthase inhibition

(2011) Simone Molz et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Chondroitin sulfate reduces cell death of rat hippocampal slices subjected to oxygen and glucose deprivation by inhibiting p38, NFκB and iNOS

(2011) María Dolores Martín-de-Saavedra et al.   NEUROCHEMISTRY INTERNATIONAL

Guanosine is neuroprotective against oxygen/glucose deprivation in hippocampal slices via large conductance Ca2+-activated K+ channels, phosphatidilinositol-3 kinase/protein kinase B pathway activation and glutamate uptake

(2011) T. Dal-Cim et al.   NEUROSCIENCE

Adenosine receptors and brain diseases: Neuroprotection and neurodegeneration

(2010) Catarina V. Gomes et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

The purinergic P2Y13 receptor activates the Nrf2/HO-1 axis and protects against oxidative stress-induced neuronal death

(2010) Sandra Espada et al.   FREE RADICAL BIOLOGY AND MEDICINE

Blockade of the MEK/ERK Pathway with a Raf Inhibitor Prevents Activation of Pro-Inflammatory Mediators in Cerebral Arteries and Reduction in Cerebral Blood Flow after Subarachnoid Hemorrhage in a Rat Model

(2010) Aida Maddahi et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Vital role of protein kinase C-related kinase in the formation and stability of neurites during hypoxia

(2010) Bettina Thauerer et al.   JOURNAL OF NEUROCHEMISTRY

Nitric oxide and neuronal death

(2010) Guy C. Brown   NITRIC OXIDE-BIOLOGY AND CHEMISTRY

Adenosine signaling and function in glial cells

(2009) D Boison et al.   CELL DEATH AND DIFFERENTIATION

Mitochondria and Reactive Oxygen Species

(2009) Francesco Addabbo et al.   HYPERTENSION

Differential NMDA receptor-dependent calcium loading and mitochondrial dysfunction in CA1 vs. CA3 hippocampal neurons

(2009) Ruslan I. Stanika et al.   NEUROBIOLOGY OF DISEASE

Guanosine-5′-monophosphate induces cell death in rat hippocampal slices via ionotropic glutamate receptors activation and glutamate uptake inhibition

(2009) Simone Molz et al.   NEUROCHEMISTRY INTERNATIONAL

Nuclear Factor-κB Activation: From Bench to Bedside

(2008) Gautam Sethi et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

p42/44 MAPK is an essential effector for purine nucleoside-mediated neuroprotection of hypoxic PC12 cells and primary cerebellar granule neurons

(2008) Bettina Tomaselli et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Mechanism of guanosine-induced neuroprotection in rat hippocampal slices submitted to oxygen–glucose deprivation

(2007) Scheyla P.B. Oleskovicz et al.   NEUROCHEMISTRY INTERNATIONAL