Development of a Gadolinium–Boron-Conjugated Albumin for MRI-Guided Neutron Capture Therapy

Next generation of boron neutron capture therapy (BNCT) agents for cancer treatment

(2023) Paolo Coghi et al.   MEDICINAL RESEARCH REVIEWS

A Potential Boron Neutron Capture Therapy Agent Selectively Suppresses High-Grade Glioma: In Vitro and in Vivo Exploration

(2023) Catalina Alamón et al.   Molecular Pharmaceutics

Efficient neutron capture therapy of glioblastoma with pteroyl-closo-dodecaborate-conjugated 4-(p-iodophenyl)butyric acid (PBC-IP)

(2023) Kai Nishimura et al.   JOURNAL OF CONTROLLED RELEASE

Gadolinium Neutron Capture Therapy (GdNCT) Agents from Molecular to Nano: Current Status and Perspectives

(2022) Son Long Ho et al.   ACS Omega

Boron encapsulated in a liposome can be used for combinational neutron capture therapy

(2022) Jiyuan Li et al.   Nature Communications

Therapeutic nucleus-access BNCT drug combined CD47-targeting gene editing in glioblastoma

(2022) Jiejian Chen et al.   JOURNAL OF NANOBIOTECHNOLOGY

In vivo evaluation of the effects of combined boron and gadolinium neutron capture therapy in mouse models

(2022) Woonghee Lee et al.   Scientific Reports

Iodophenyl-conjugated closo-dodecaborate as a promising small boron molecule that binds to serum albumin and accumulates in tumor

(2022) Kai Nishimura et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

RGD Peptide-Conjugated Dodecaborate with the Ga-DOTA Complex: A Preliminary Study for the Development of Theranostic Agents for Boron Neutron Capture Therapy and Its Companion Diagnostics

(2022) Kenji Mishiro et al.   Journal of Medicinal Chemistry

Design, Synthesis, and Biological Evaluation of Boron-Containing Macrocyclic Polyamines and Their Zinc(II) Complexes for Boron Neutron Capture Therapy

(2021) Hiroki Ueda et al.   JOURNAL OF MEDICINAL CHEMISTRY

Poly(vinyl alcohol) boosting therapeutic potential of p-boronophenylalanine in neutron capture therapy by modulating metabolism

(2020) Takahiro Nomoto et al.   Science Advances

Gamma-ray spectra from thermal neutron capture on gadolinium-155 and natural gadolinium

(2020) Tomoyuki Tanaka et al.   Progress of Theoretical and Experimental Physics

Bimodal Therapeutic Agents against Glioblastoma, one of the most Lethal Cancer

(2020) Hugo Eduardo Cerecetto et al.   CHEMISTRY-A EUROPEAN JOURNAL

Long-term outcome of cutaneous melanoma patients treated with boron neutron capture therapy (BNCT)

(2020) Junichi Hiratsuka et al.   JOURNAL OF RADIATION RESEARCH

Cyclic RGD-Functionalized closo-Dodecaborate Albumin Conjugates as Integrin Targeting Boron Carriers for Neutron Capture Therapy

(2020) Kazuki Kawai et al.   MOLECULAR PHARMACEUTICS

Design, Synthesis, and Evaluation of Lipopeptide Conjugates of Mercaptoundecahydrododecaborate for Boron Neutron Capture Therapy

(2019) Aoi Isono et al.   ChemMedChem

4-Borono-2-18F-fluoro-l-phenylalanine PET for boron neutron capture therapy-oriented diagnosis: overview of a quarter century of research

(2019) Kiichi Ishiwata   ANNALS OF NUCLEAR MEDICINE

Boron neutron capture therapy (BNCT): a unique role in radiotherapy with a view to entering the accelerator-based BNCT era

(2019) Minoru Suzuki   International Journal of Clinical Oncology

Boron agents for neutron capture therapy

(2019) Kuan Hu et al.   COORDINATION CHEMISTRY REVIEWS

closo-Dodecaborate-conjugated human serum albumins: preparation and in vivo selective boron delivery to tumor

(2018) Hiroyuki Nakamura et al.   PURE AND APPLIED CHEMISTRY

Chemistry of MRI Contrast Agents: Current Challenges and New Frontiers

(2018) Jessica Wahsner et al.   CHEMICAL REVIEWS

Maleimide-functionalized closo-dodecaborate albumin conjugates (MID-AC): Unique ligation at cysteine and lysine residues enables efficient boron delivery to tumor for neutron capture therapy

(2016) Shunsuke Kikuchi et al.   JOURNAL OF CONTROLLED RELEASE

Boronophenylalanine, a boron delivery agent for boron neutron capture therapy, is transported by ATB0,+, LAT1 and LAT2

(2015) Printip Wongthai et al.   CANCER SCIENCE

Advancements in Tumor Targeting Strategies for Boron Neutron Capture Therapy

(2015) Micah John Luderer et al.   PHARMACEUTICAL RESEARCH

Critical review, with an optimistic outlook, on Boron Neutron Capture Therapy (BNCT)

(2013) Raymond L. Moss   APPLIED RADIATION AND ISOTOPES

Development of High Boron Content Liposomes and Their Promising Antitumor Effect for Neutron Capture Therapy of Cancers

(2012) Hayato Koganei et al.   BIOCONJUGATE CHEMISTRY

A Carborane-Derivative “Click” Reaction under Heterogeneous Conditions for the Synthesis of a Promising Lipophilic MRI/GdBNCT Agent

(2012) Antonio Toppino et al.   CHEMISTRY-A EUROPEAN JOURNAL

Current status of boron neutron capture therapy of high grade gliomas and recurrent head and neck cancer

(2012) Rolf F Barth et al.   Radiation Oncology

MRI-Guided Neutron Capture Therapy by Use of a Dual Gadolinium/Boron Agent Targeted at Tumour Cells through Upregulated Low-Density Lipoprotein Transporters

(2011) Simonetta Geninatti-Crich et al.   CHEMISTRY-A EUROPEAN JOURNAL

L-Amino Acid Transporter-1 and Boronophenylalanine-Based Boron Neutron Capture Therapy of Human Brain Tumors

(2009) A. Detta et al.   CANCER RESEARCH

Influence of molecular parameters and increasing magnetic field strength on relaxivity of gadolinium- and manganese-based T1contrast agents

(2009) Peter Caravan et al.   Contrast Media & Molecular Imaging