Iodophenyl-conjugated closo-dodecaborate as a promising small boron molecule that binds to serum albumin and accumulates in tumor

Designation Products: Boron Neutron Capture Therapy for Head and Neck Carcinoma

(2021) Hitoshi Kanno et al.   ONCOLOGIST

Cyclic RGD-Functionalized closo-Dodecaborate Albumin Conjugates as Integrin Targeting Boron Carriers for Neutron Capture Therapy

(2020) Kazuki Kawai et al.   MOLECULAR PHARMACEUTICS

Boron neutron capture therapy using cyclotron-based epithermal neutron source and borofalan (10B) for recurrent or locally advanced head and neck cancer (JHN002): An open-label phase II trial

(2020) Katsumi Hirose et al.   RADIOTHERAPY AND ONCOLOGY

Integrins in wound healing, fibrosis and tumor stroma: High potential targets for therapeutics and drug delivery

(2018) Jonas Schnittert et al.   ADVANCED DRUG DELIVERY REVIEWS

Synthesis and Applications of Perfunctionalized Boron Clusters

(2018) Jonathan C. Axtell et al.   INORGANIC CHEMISTRY

Synthesis and biological evaluation of closo -dodecaborate ibuprofen conjugate (DIC) as a new boron agent for neutron capture therapy

(2018) Satomu Ishii et al.   JOURNAL OF ORGANOMETALLIC CHEMISTRY

Albumin-Binding Evans Blue Derivatives for Diagnostic Imaging and Production of Long-Acting Therapeutics

(2016) Orit Jacobson et al.   BIOCONJUGATE CHEMISTRY

Simple bioconjugate chemistry serves great clinical advances: albumin as a versatile platform for diagnosis and precision therapy

(2016) Zhibo Liu et al.   CHEMICAL SOCIETY REVIEWS

Maleimide-functionalized closo-dodecaborate albumin conjugates (MID-AC): Unique ligation at cysteine and lysine residues enables efficient boron delivery to tumor for neutron capture therapy

(2016) Shunsuke Kikuchi et al.   JOURNAL OF CONTROLLED RELEASE

Boron neutron capture therapy outcomes for advanced or recurrent head and neck cancer

(2013) M. Suzuki et al.   JOURNAL OF RADIATION RESEARCH

Impact of albumin on drug delivery — New applications on the horizon

(2011) Bakheet Elsadek et al.   JOURNAL OF CONTROLLED RELEASE

L-Amino Acid Transporter-1 and Boronophenylalanine-Based Boron Neutron Capture Therapy of Human Brain Tumors

(2009) A. Detta et al.   CANCER RESEARCH

A Portable Albumin Binder from a DNA-Encoded Chemical Library

(2008) Christoph E. Dumelin et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Boron neutron capture therapy for glioblastoma

(2008) Tetsuya Yamamoto et al.   CANCER LETTERS

Practical synthesis of 1,4-dioxane derivative of the closo-dodecaborate anion and its ring opening with acetylenic alkoxides

(2007) Igor B. Sivaev et al.   JOURNAL OF ORGANOMETALLIC CHEMISTRY