Design, Synthesis, and Biological Evaluation of Boron-Containing Macrocyclic Polyamines and Their Zinc(II) Complexes for Boron Neutron Capture Therapy

Boron Chemistry for Medical Applications

(2020) Fayaz Ali et al.   MOLECULES

Sensing Zn2+ in Aqueous Solution with a Fluorescent Scorpiand Macrocyclic Ligand Decorated with an Anthracene Bearing Tail

(2020) Matteo Savastano et al.   MOLECULES

Evaluation of a Novel Boron-Containing α-d-Mannopyranoside for BNCT

(2020) Takao Tsurubuchi et al.   Cells

Cyclic RGD-Functionalized closo-Dodecaborate Albumin Conjugates as Integrin Targeting Boron Carriers for Neutron Capture Therapy

(2020) Kazuki Kawai et al.   MOLECULAR PHARMACEUTICS

Design, Synthesis, and Evaluation of Lipopeptide Conjugates of Mercaptoundecahydrododecaborate for Boron Neutron Capture Therapy

(2019) Aoi Isono et al.   ChemMedChem

Anomeric sugar boronic acid analogues as potential agents for boron neutron capture therapy

(2019) Daniela Imperio et al.   Beilstein Journal of Organic Chemistry

Boron neutron capture therapy (BNCT): a unique role in radiotherapy with a view to entering the accelerator-based BNCT era

(2019) Minoru Suzuki   International Journal of Clinical Oncology

The Zn(II)-1,4,7-Trimethyl-1,4,7-Triazacyclononane Complex: A Monometallic Catalyst Active in Two Protonation States

(2019) Marta Diez-Castellnou et al.   Frontiers in Chemistry

Thermal Sensitive Liposomes Improve Delivery of Boronated Agents for Boron Neutron Capture Therapy

(2019) Micah John Luderer et al.   PHARMACEUTICAL RESEARCH

Evaluation of Zn2+ Coordination Structures in Chiral Zn2+ Complexes Based on Shape Measurement Factors: Relationships between Activity and the Coordination Structure

(2019) Shin Aoki et al.   EUROPEAN JOURNAL OF INORGANIC CHEMISTRY

A Short and Convenient Synthesis of closo -Dodecaborate Sugar Conjugates

(2019) Daniela Imperio et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Application of Nitroimidazole–Carbobane-Modified Phenylalanine Derivatives as Dual-Target Boron Carriers in Boron Neutron Capture Therapy

(2019) Ruixi Li et al.   MOLECULAR PHARMACEUTICS

A Bis-Triazacyclononane Tris-Pyridyl N9 -Azacryptand “Beer Can” Receptor for Complexation of Alkali Metal and Lead(II) Cations

(2018) Asha Brown et al.   CHEMISTRY-A EUROPEAN JOURNAL

Proteoglycans—Biomarkers and Targets in Cancer Therapy

(2018) Dragana Nikitovic et al.   Frontiers in Endocrinology

Design and synthesis of boron containing monosaccharides by the hydroboration of d-glucal for use in boron neutron capture therapy (BNCT)

(2018) Taiki Itoh et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Proposal for determining absolute biological effectiveness of boron neutron capture therapy—the effect of 10B(n,α)7Li dose can be predicted from the nucleocytoplasmic ratio or the cell size

(2018) Koji Ono et al.   JOURNAL OF RADIATION RESEARCH

Synthesis of Sugar–Boronic Acid Derivatives: A Class of Potential Agents for Boron Neutron Capture Therapy

(2017) Daniela Imperio et al.   ORGANIC LETTERS

Evaluation of a novel sodium borocaptate-containing unnatural amino acid as a boron delivery agent for neutron capture therapy of the F98 rat glioma

(2017) Gen Futamura et al.   Radiation Oncology

Cationic lipids with a cyclen headgroup: synthesis and structure–activity relationship studies as non-viral gene vectors

(2017) De-Chun Chang et al.   RSC Advances

Targeting polyamine metabolism for cancer therapy and prevention

(2016) T. R. Murray-Stewart et al.   BIOCHEMICAL JOURNAL

Comparison of the pharmacokinetics between L-BPA and L-FBPA using the same administration dose and protocol: a validation study for the theranostic approach using [18F]-L-FBPA positron emission tomography in boron neutron capture therapy

(2016) Tsubasa Watanabe et al.   BMC CANCER

11B NMR Probes of Copper(II): Finding and Implications of the Cu2+-Promoted Decomposition ofortho-Carborane Derivatives

(2016) Tomohiro Tanaka et al.   EUROPEAN JOURNAL OF INORGANIC CHEMISTRY

11B NMR/MRI Sensing of Copper(II) Ions In Vitro by the Decomposition of a Hybrid Compound of anido-o-Carborane and a Metal Chelator

(2016) Tomohiro Tanaka et al.   EUROPEAN JOURNAL OF INORGANIC CHEMISTRY

Biological activity of N(4)-boronated derivatives of 2′-deoxycytidine, potential agents for boron-neutron capture therapy

(2015) Joanna Nizioł et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Boronophenylalanine, a boron delivery agent for boron neutron capture therapy, is transported by ATB0,+, LAT1 and LAT2

(2015) Printip Wongthai et al.   CANCER SCIENCE

Remaining Mysteries of Molecular Biology: The Role of Polyamines in the Cell

(2015) Leonor Miller-Fleming et al.   JOURNAL OF MOLECULAR BIOLOGY

Chitosan Grafted with Phosphorylcholine and Macrocyclic Polyamine as an Effective Gene Delivery Vector: Preparation, Characterization and In Vitro Transfection

(2015) Ling Li et al.   MACROMOLECULAR BIOSCIENCE

Synthesis of oligo-closo-dodecaborates by Hüisgen click reaction as encapsulated agents for the preparation of high-boron-content liposomes for neutron capture therapy

(2015) Hayato Koganei et al.   NEW JOURNAL OF CHEMISTRY

Advancements in Tumor Targeting Strategies for Boron Neutron Capture Therapy

(2015) Micah John Luderer et al.   PHARMACEUTICAL RESEARCH

Synthesis and in vitro evaluation of thiododecaborated α, α- cycloalkylamino acids for the treatment of malignant brain tumors by boron neutron capture therapy

(2014) Yoshihide Hattori et al.   AMINO ACIDS

Synthesis, reactivity and biological activity of N(4)-boronated derivatives of 2′-deoxycytidine

(2014) Joanna Nizioł et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Receptor-Mediated Uptake of Boron-Rich Neuropeptide Y Analogues for Boron Neutron Capture Therapy

(2014) Verena M. Ahrens et al.   ChemMedChem

Design and Synthesis of Chiral Zn2+ Complexes Mimicking Natural Aldolases for Catalytic C–C Bond Forming Reactions in Aqueous Solution

(2014) Susumu Itoh et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

ColonyArea: An ImageJ Plugin to Automatically Quantify Colony Formation in Clonogenic Assays

(2014) Camilo Guzmán et al.   PLoS One

Polyamines and membrane transporters

(2013) Ahmed A. Abdulhussein et al.   AMINO ACIDS

Reaction-Based and Single Fluorescent Emitter Decorated Ratiometric Nanoprobe to Detect Hydrogen Peroxide

(2013) Chun-Yen Chen et al.   CHEMISTRY-A EUROPEAN JOURNAL

Polyamines and cancer: implications for chemotherapy and chemoprevention

(2013) Shannon L. Nowotarski et al.   EXPERT REVIEWS IN MOLECULAR MEDICINE

Boron neutron capture therapy outcomes for advanced or recurrent head and neck cancer

(2013) M. Suzuki et al.   JOURNAL OF RADIATION RESEARCH

Heparan sulfate proteoglycan as a cell-surface endocytosis receptor

(2013) Helena C. Christianson et al.   MATRIX BIOLOGY

Synthesis and cellular studies of polyamine conjugates of a mercaptomethyl–carboranylporphyrin

(2012) N.V.S. Dinesh K. Bhupathiraju et al.   BIOORGANIC & MEDICINAL CHEMISTRY

New classes of carborane-appended 5-thio-d-glucopyranose derivatives

(2012) Rashmirekha Satapathy et al.   DALTON TRANSACTIONS

Structural Basis for Bifunctional Zinc(II) Macrocyclic Complex Recognition of Thymine Bulges in DNA

(2012) Imee Marie A. del Mundo et al.   INORGANIC CHEMISTRY

Biological Evaluation of Dodecaborate-Containing l-Amino Acids for Boron Neutron Capture Therapy

(2012) Yoshihide Hattori et al.   JOURNAL OF MEDICINAL CHEMISTRY

NIH Image to ImageJ: 25 years of image analysis

(2012) Caroline A Schneider et al.   NATURE METHODS

Current status of boron neutron capture therapy of high grade gliomas and recurrent head and neck cancer

(2012) Rolf F Barth et al.   Radiation Oncology

Chitosan Grafted with Macrocyclic Polyamines on C-2 and C-6 Positions as Nonviral Gene Vectors: Preparation, Characterization, and In Vitro Transfection Studies

(2011) Chao Li et al.   BIOMACROMOLECULES

Self-assembly and selective exchange of oligoanions on the surface of monolayer protected Au nanoparticles in water

(2011) Grégory Pieters et al.   CHEMICAL COMMUNICATIONS

11B NMR Sensing of d-Block Metal Ions in Vitro and in Cells Based on the Carbon–Boron Bond Cleavage of Phenylboronic Acid-Pendant Cyclen (Cyclen = 1,4,7,10-Tetraazacyclododecane)

(2011) Masanori Kitamura et al.   INORGANIC CHEMISTRY

Polyamine transport is mediated by both endocytic and solute carrier transport mechanisms in the gastrointestinal tract

(2010) Takeshi Uemura et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Dodecaborate lipid liposomes as new vehicles for boron delivery system of neutron capture therapy

(2010) Manabu Ueno et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Amiloride inhibits macropinocytosis by lowering submembranous pH and preventing Rac1 and Cdc42 signaling

(2010) Mirkka Koivusalo et al.   JOURNAL OF CELL BIOLOGY

Tripodal Tris-tacn and Tris-dpa Platforms for Assembling Phosphate-Templated Trimetallic Centers

(2010) Rui Cao et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The polyamine transport system as a target for anticancer drug development

(2009) Andrew J. Palmer et al.   AMINO ACIDS

Biological evaluation of boronated unnatural amino acids as new boron carriers

(2009) G.W. Kabalka et al.   APPLIED RADIATION AND ISOTOPES

Chiral Catalysts Dually Functionalized with Amino Acid and Zn2+Complex Components for Enantioselective Direct Aldol Reactions Inspired by Natural Aldolases: Design, Synthesis, Complexation Properties, Catalytic Activities, and Mechanistic Study

(2009) Susumu Itoh et al.   CHEMISTRY-A EUROPEAN JOURNAL

Boron-Containing Protoporphyrin IX Derivatives and Their Modification for Boron Neutron Capture Therapy: Synthesis, Characterization, and Comparative In Vitro Toxicity Evaluation

(2009) Mohamed E. El-Zaria et al.   CHEMISTRY-A EUROPEAN JOURNAL

Design and Synthesis of a Stable Supramolecular Trigonal Prism Formed by the Self-Assembly of a Linear Tetrakis(Zn2+−cyclen) Complex and Trianionic Trithiocyanuric Acid in Aqueous Solution and Its Complexation with DNA (Cyclen = 1,4,7,10-Tetraazacyclododecane)

(2009) Mohd Zulkefeli et al.   INORGANIC CHEMISTRY

Design and Synthesis of a Fluorescent Probe for Zn2+, 5,7-Bis(N,N-dimethylaminosulfonyl)-8-hydroxyquinoline-Pendant 1,4,7,10-Tetraazacyclododecane and Zn2+-Dependent Hydrolytic and Zn2+-Independent Photochemical Reactivation of Its Benzenesulfonyl-Caged Derivative

(2009) Ryosuke Ohshima et al.   INORGANIC CHEMISTRY

Recent Advances in the Development of Polyamine Analogues as Antitumor Agents§

(2009) Robert A. Casero et al.   JOURNAL OF MEDICINAL CHEMISTRY

Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation

(2009) M. G. Vander Heiden et al.   SCIENCE

Novel glycosylated carboranylquinazolines for boron neutron capture therapy of tumors: synthesis, characterization, andin vitro toxicity studies

(2008) Afaf R. Genady et al.   APPLIED ORGANOMETALLIC CHEMISTRY