Arf6 is required for endocytosis and filamentous actin assembly during angiogenesis in vitro

Trafficking in blood vessel development

(2022) Caitlin R. Francis et al.   ANGIOGENESIS

Rab35 governs apicobasal polarity through regulation of actin dynamics during sprouting angiogenesis

(2022) Caitlin R. Francis et al.   Nature Communications

Targeting EGFR-dependent tumors by disrupting an ARF6-mediated sorting system

(2022) Huiling Guo et al.   Nature Communications

Integrin Conformational Dynamics and Mechanotransduction

(2022) Reza Kolasangiani et al.   Cells

Notch regulates vascular collagen IV basement membrane through modulation of lysyl hydroxylase 3 trafficking

(2021) Stephen J. Gross et al.   ANGIOGENESIS

Synaptotagmin-Like Protein 2a Regulates Angiogenic Lumen Formation via Weibel-Palade Body Apical Secretion of Angiopoietin-2

(2021) Caitlin R. Francis et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Capturing membrane trafficking events during 3D angiogenic development in vitro

(2021) Caitlin R. Francis et al.   MICROCIRCULATION

Arf6 Can Trigger Wave Regulatory Complex-Dependent Actin Assembly Independent of Arno

(2020) Vikash Singh et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Arf•GAPs as Regulators of the Actin Cytoskeleton—An Update

(2019) Christine Tanna et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Type I myosins anchor actin assembly to the plasma membrane during clathrin-mediated endocytosis

(2019) Ross T.A. Pedersen et al.   JOURNAL OF CELL BIOLOGY

The Small GTPase Arf6: An Overview of Its Mechanisms of Action and of Its Role in Host–Pathogen Interactions and Innate Immunity

(2019) Tim Van Acker et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Endophilin-A2 dependent VEGFR2 endocytosis promotes sprouting angiogenesis

(2019) Gael Genet et al.   Nature Communications

The C-terminal domain of EFA6A interacts directly with F-actin and assembles F-actin bundles

(2019) Eric Macia et al.   Scientific Reports

The Rab-effector protein RABEP2 regulates endosomal trafficking to mediate vascular endothelial growth factor receptor-2 (VEGFR2)-dependent signaling

(2018) Natalie Kofler et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mechanisms of clathrin-mediated endocytosis

(2018) Marko Kaksonen et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

GEP100/ARF6 regulates VEGFR2 signaling to facilitate high glucose induced epithelial-mesenchymal transition and cell permeability in RPE cells

(2018) Zhi-Peng You et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Small GTPase ARF6 controls VEGFR2 trafficking and signaling in diabetic retinopathy

(2017) Weiquan Zhu et al.   JOURNAL OF CLINICAL INVESTIGATION

Roles of Arf6 in cancer cell invasion, metastasis and proliferation

(2017) Rui Li et al.   LIFE SCIENCES

Dynasore impairs VEGFR2 signalling in an endocytosis-independent manner

(2017) Dimitris Basagiannis et al.   Scientific Reports

Mechanisms and regulation of endothelial VEGF receptor signalling

(2016) Michael Simons et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Cdc42 and k-Ras Control Endothelial Tubulogenesis through Apical Membrane and Cytoskeletal Polarization: Novel Stimulatory Roles for GTPase Effectors, the Small GTPases, Rac2 and Rap1b, and Inhibitory Influence of Arhgap31 and Rasa1

(2016) Pieter R. Norden et al.   PLoS One

Arf6 regulates tumour angiogenesis and growth through HGF-induced endothelial β1 integrin recycling

(2015) Tsunaki Hongu et al.   Nature Communications

ARF6 Inhibition Stabilizes the Vasculature and Enhances Survival during Endotoxic Shock

(2014) C. T. Davis et al.   JOURNAL OF IMMUNOLOGY

Rab35, acting through ACAP2 switching off Arf6, negatively regulates oligodendrocyte differentiation and myelination

(2014) Yuki Miyamoto et al.   MOLECULAR BIOLOGY OF THE CELL

Endocytosis of hERG Is Clathrin-Independent and Involves Arf6

(2014) Rucha Karnik et al.   PLoS One

EFA6 controls Arf1 and Arf6 activation through a negative feedback loop

(2014) D. Padovani et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Small Molecules CK-666 and CK-869 Inhibit Actin-Related Protein 2/3 Complex by Blocking an Activating Conformational Change

(2013) Byron Hetrick et al.   CHEMISTRY & BIOLOGY

Dynamic Localization of G-Actin during Membrane Protrusion in Neuronal Motility

(2013) Chi Wai Lee et al.   CURRENT BIOLOGY

Integrins in mechanotransduction

(2013) Tyler D Ross et al.   CURRENT OPINION IN CELL BIOLOGY

Phosphatidylinositol 4,5-bisphosphate clusters act as molecular beacons for vesicle recruitment

(2013) Alf Honigmann et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Grp1-associated scaffold protein (GRASP) is a regulator of the ADP ribosylation factor 6 (Arf6)-dependent membrane trafficking pathway

(2012) Anand Venkataraman et al.   CELL BIOLOGY INTERNATIONAL

ARF6 Directs Axon Transport and Traffic of Integrins and Regulates Axon Growth in Adult DRG Neurons

(2012) R. Eva et al.   JOURNAL OF NEUROSCIENCE

Interleukin receptor activates a MYD88–ARNO–ARF6 cascade to disrupt vascular stability

(2012) Weiquan Zhu et al.   NATURE

ARF family G proteins and their regulators: roles in membrane transport, development and disease

(2011) Julie G. Donaldson et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

A molecular network for de novo generation of the apical surface and lumen

(2010) David M. Bryant et al.   NATURE CELL BIOLOGY

Actin and endocytosis: mechanisms and phylogeny

(2009) Brian J Galletta et al.   CURRENT OPINION IN CELL BIOLOGY

Cellular and Molecular Mechanisms of Vascular Lumen Formation

(2009) M. Luisa Iruela-Arispe et al.   DEVELOPMENTAL CELL

Slit2–Robo4 signalling promotes vascular stability by blocking Arf6 activity

(2009) Christopher A. Jones et al.   NATURE CELL BIOLOGY

Enzymatic assembly of DNA molecules up to several hundred kilobases

(2009) Daniel G Gibson et al.   NATURE METHODS

A Versatile Viral System for Expression and Depletion of Proteins in Mammalian Cells

(2009) Eric Campeau et al.   PLoS One

Clathrin-independent endocytosis: A unique platform for cell signaling and PM remodeling

(2008) J DONALDSON et al.   CELLULAR SIGNALLING

Taking apart the endocytic machinery: Figure 1.

(2008) Marko Kaksonen   JOURNAL OF CELL BIOLOGY