Cell fate in animal and human blastocysts and the determination of viability

Defining the three cell lineages of the human blastocyst by single-cell RNA-seq

(2015) Paul Blakeley et al.   DEVELOPMENT

Lineage-Specific Profiling Delineates the Emergence and Progression of Naive Pluripotency in Mammalian Embryogenesis

(2015) Thorsten Boroviak et al.   DEVELOPMENTAL CELL

WNT3 and membrane-associated β-catenin regulate trophectoderm lineage differentiation in human blastocysts

(2015) M. Krivega et al.   MOLECULAR HUMAN REPRODUCTION

Single cells get together: High-resolution approaches to study the dynamics of early mouse development

(2015) Néstor Saiz et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

WNT/β-Catenin Signaling Affects Cell Lineage and Pluripotency-Specific Gene Expression in Bovine Blastocysts: Prospects for Bovine Embryonic Stem Cell Derivation

(2015) Zofia Eliza Madeja et al.   STEM CELLS AND DEVELOPMENT

Pluripotency in the light of the developmental hourglass

(2014) Ewart Kuijk et al.   BIOLOGICAL REVIEWS

Specific gene-regulation networks during the pre-implantation development of the pig embryo as revealed by deep sequencing

(2014) Suying Cao et al.   BMC GENOMICS

A close look at the mammalian blastocyst: epiblast and primitive endoderm formation

(2014) Jérôme Artus et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

GATA6 Levels Modulate Primitive Endoderm Cell Fate Choice and Timing in the Mouse Blastocyst

(2014) Nadine Schrode et al.   DEVELOPMENTAL CELL

The WNT signaling antagonist Dickkopf-1 directs lineage commitment and promotes survival of the preimplantation embryo

(2014) Anna C. Denicol et al.   FASEB JOURNAL

Candidate gene expression patterns in rabbit preimplantation embryos developed in vivo and in vitro

(2014) Gibence Rose Winnie Henderson et al.   JOURNAL OF ASSISTED REPRODUCTION AND GENETICS

Totipotency and lineage segregation in the human embryo

(2014) C. De Paepe et al.   MOLECULAR HUMAN REPRODUCTION

Developmental differences in the expression of FGF receptors between human and mouse embryos

(2014) T. Kunath et al.   PLACENTA

HIPPO Pathway Members Restrict SOX2 to the Inner Cell Mass Where It Promotes ICM Fates in the Mouse Blastocyst

(2014) Eryn Wicklow et al.   PLoS Genetics

Changes in sub-cellular localisation of trophoblast and inner cell mass specific transcription factors during bovine preimplantation development

(2013) Zofia E Madeja et al.   BMC DEVELOPMENTAL BIOLOGY

Porcn-dependent Wnt signaling is not required prior to mouse gastrulation

(2013) S. Biechele et al.   DEVELOPMENT

FGF4 is a limiting factor controlling the proportions of primitive endoderm and epiblast in the ICM of the mouse blastocyst

(2013) Dayana Krawchuk et al.   DEVELOPMENTAL BIOLOGY

Cadherin-dependent filopodia control preimplantation embryo compaction

(2013) Juan Carlos Fierro-González et al.   NATURE CELL BIOLOGY

Canonical WNT signaling regulates development of bovine embryos to the blastocyst stage

(2013) Anna C. Denicol et al.   Scientific Reports

The hypoblast (visceral endoderm): an evo-devo perspective

(2012) C. D. Stern et al.   DEVELOPMENT

The roles of FGF and MAP kinase signaling in the segregation of the epiblast and hypoblast cell lineages in bovine and human embryos

(2012) E. W. Kuijk et al.   DEVELOPMENT

FGF4 is required for lineage restriction and salt-and-pepper distribution of primitive endoderm factors but not their initial expression in the mouse

(2012) M. Kang et al.   DEVELOPMENT

Analysis of human embryos from zygote to blastocyst reveals distinct gene expression patterns relative to the mouse

(2012) Kathy K. Niakan et al.   DEVELOPMENTAL BIOLOGY

Human trophectoderm cells are not yet committed

(2012) C. De Paepe et al.   HUMAN REPRODUCTION

Early cell fate decisions in the mouse embryo

(2012) Néstor Saiz et al.   REPRODUCTION

Possible involvement of Wnt/β-catenin signaling pathway in hatching and trophectoderm differentiation of pig blastocysts

(2012) Kyung Tae Lim et al.   THERIOGENOLOGY

BRACHYURY and CDX2 Mediate BMP-Induced Differentiation of Human and Mouse Pluripotent Stem Cells into Embryonic and Extraembryonic Lineages

(2011) Andreia S. Bernardo et al.   Cell Stem Cell

Differential plasticity of epiblast and primitive endoderm precursors within the ICM of the early mouse embryo

(2011) J. B. Grabarek et al.   DEVELOPMENT

Human hypoblast formation is not dependent on FGF signalling

(2011) Mila Roode et al.   DEVELOPMENTAL BIOLOGY

Trophectoderm Lineage Determination in Cattle

(2011) Debra K. Berg et al.   DEVELOPMENTAL CELL

Primitive Endoderm Differentiates via a Three-Step Mechanism Involving Nanog and RTK Signaling

(2011) Stephen Frankenberg et al.   DEVELOPMENTAL CELL

Isolated mouse inner cell mass is unable to reconstruct trophectoderm

(2011) Katarzyna Szczepanska et al.   DIFFERENTIATION

Which morphological scoring system is relevant in human embryo development?

(2011) Markus Montag et al.   PLACENTA

Effect of different culture systems on mRNA expression in developing rabbit embryos

(2011) M.D. Saenz-de-Juano et al.   ZYGOTE

Cell Polarity Regulator PARD6B Is Essential for Trophectoderm Formation in the Preimplantation Mouse Embryo1

(2010) Vernadeth B. Alarcon   BIOLOGY OF REPRODUCTION

Gata3 regulates trophoblast development downstream of Tead4 and in parallel to Cdx2

(2010) A. Ralston et al.   DEVELOPMENT

FGF signal-dependent segregation of primitive endoderm and epiblast in the mouse blastocyst

(2010) Y. Yamanaka et al.   DEVELOPMENT

The role of FGF/Erk signaling in pluripotent cells

(2010) F. Lanner et al.   DEVELOPMENT

Mechanisms of trophectoderm fate specification in preimplantation mouse development

(2010) Hiroshi Sasaki   DEVELOPMENT GROWTH & DIFFERENTIATION

Nanog is required for primitive endoderm formation through a non-cell autonomous mechanism

(2010) Daniel M. Messerschmidt et al.   DEVELOPMENTAL BIOLOGY

The primitive endoderm lineage of the mouse blastocyst: Sequential transcription factor activation and regulation of differentiation by Sox17

(2010) Jérôme Artus et al.   DEVELOPMENTAL BIOLOGY

Resolution of Cell Fate Decisions Revealed by Single-Cell Gene Expression Analysis from Zygote to Blastocyst

(2010) Guoji Guo et al.   DEVELOPMENTAL CELL

Three-dimensional localisation of NANOG, OCT4, and E-cadherin in porcine pre- and peri-implantation embryos

(2010) Xenia Asbaek Wolf et al.   DEVELOPMENTAL DYNAMICS

Sox17 promotes differentiation in mouse embryonic stem cells by directly regulating extraembryonic gene expression and indirectly antagonizing self-renewal

(2010) K. K. Niakan et al.   GENES & DEVELOPMENT

The role of YAP transcription coactivator in regulating stem cell self-renewal and differentiation

(2010) I. Lian et al.   GENES & DEVELOPMENT

Nanog Is the Gateway to the Pluripotent Ground State

(2009) Jose Silva et al.   CELL

Optimal Timing of Inner Cell Mass Isolation Increases the Efficiency of Human Embryonic Stem Cell Derivation and Allows Generation of Sibling Cell Lines

(2009) Alice E. Chen et al.   Cell Stem Cell

Suppression of Erk signalling promotes ground state pluripotency in the mouse embryo

(2009) J. Nichols et al.   DEVELOPMENT

Active cell movements coupled to positional induction are involved in lineage segregation in the mouse blastocyst

(2009) Sigolène M. Meilhac et al.   DEVELOPMENTAL BIOLOGY

The Hippo Signaling Pathway Components Lats and Yap Pattern Tead4 Activity to Distinguish Mouse Trophectoderm from Inner Cell Mass

(2009) Noriyuki Nishioka et al.   DEVELOPMENTAL CELL

GATA3 Is Selectively Expressed in the Trophectoderm of Peri-implantation Embryo and Directly RegulatesCdx2Gene Expression

(2009) Pratik Home et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Comparative aspects of implantation

(2009) Fuller W Bazer et al.   REPRODUCTION

Inner Cell Mass Localization of NANOG Precedes OCT3/4 in Rhesus Monkey Blastocysts

(2009) A.J. Harvey et al.   STEM CELLS AND DEVELOPMENT

Distinct sequential cell behaviours direct primitive endoderm formation in the mouse blastocyst

(2008) B. Plusa et al.   DEVELOPMENT

Blastomeres of the mouse embryo lose totipotency after the fifth cleavage division: Expression of Cdx2 and Oct4 and developmental potential of inner and outer blastomeres of 16- and 32-cell embryos

(2008) Aneta Suwińska et al.   DEVELOPMENTAL BIOLOGY

The Endoderm of the Mouse Embryo Arises by Dynamic Widespread Intercalation of Embryonic and Extraembryonic Lineages

(2008) Gloria S. Kwon et al.   DEVELOPMENTAL CELL

Differences in early lineage segregation between mammals

(2008) Ewart W. Kuijk et al.   DEVELOPMENTAL DYNAMICS

Markers that define stemness in ESC are unable to identify the totipotent cells in human preimplantation embryos

(2008) G. Cauffman et al.   HUMAN REPRODUCTION

Novel strategy with potential to identify developmentally competent IVF blastocysts

(2008) G. M. Jones et al.   HUMAN REPRODUCTION

Expression of genes involved in early cell fate decisions in human embryos and their regulation by growth factors

(2008) S J Kimber et al.   REPRODUCTION

Cdx2 acts downstream of cell polarization to cell-autonomously promote trophectoderm fate in the early mouse embryo

(2007) Amy Ralston et al.   DEVELOPMENTAL BIOLOGY

Tead4 is required for specification of trophectoderm in pre-implantation mouse embryos

(2007) Noriyuki Nishioka et al.   MECHANISMS OF DEVELOPMENT

Morphogenesis of the mammalian blastocyst

(2007) Nicolas Dard et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Virtues and limitations of the preimplantation mouse embryo as a model system

(2007) Robert A. Taft   THERIOGENOLOGY