Pluripotency in the light of the developmental hourglass

Nanog Is Dispensable for the Generation of Induced Pluripotent Stem Cells

(2014) Benjamin A. Schwarz et al.   CURRENT BIOLOGY

Nanog-Independent Reprogramming to iPSCs with Canonical Factors

(2014) Ava C. Carter et al.   Stem Cell Reports

Developmental Fate and Cellular Maturity Encoded in Human Regulatory DNA Landscapes

(2013) Andrew B. Stergachis et al.   CELL

The Hippo Pathway Member Nf2 Is Required for Inner Cell Mass Specification

(2013) Katie Cockburn et al.   CURRENT BIOLOGY

Development: Hippo Signalling Turns the Embryo Inside Out

(2013) Miguel Manzanares et al.   CURRENT BIOLOGY

Polarity-Dependent Distribution of Angiomotin Localizes Hippo Signaling in Preimplantation Embryos

(2013) Yoshikazu Hirate et al.   CURRENT BIOLOGY

Different flavors of X-chromosome inactivation in mammals

(2013) Cathérine Dupont et al.   CURRENT OPINION IN CELL BIOLOGY

Karl Ernst von Baer (1792-1876) and Evolution

(2013) Sabine Brauckmann   INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY

EED and KDM6B Coordinate the First Mammalian Cell Lineage Commitment To Ensure Embryo Implantation

(2013) B. Saha et al.   MOLECULAR AND CELLULAR BIOLOGY

The maternal to zygotic transition in mammals

(2013) Lei Li et al.   MOLECULAR ASPECTS OF MEDICINE

Topology of mammalian developmental enhancers and their regulatory landscapes

(2013) Wouter de Laat et al.   NATURE

Genetic programs in human and mouse early embryos revealed by single-cell RNA sequencing

(2013) Zhigang Xue et al.   NATURE

Derivation of novel human ground state naive pluripotent stem cells

(2013) Ohad Gafni et al.   NATURE

A Comparative Analysis of Transcription Factor Expression during Metazoan Embryonic Development

(2013) Alicia N. Schep et al.   PLoS One

JNK1 and 2 play a negative role in reprogramming to pluripotent stem cells by suppressing Klf4 activity

(2013) Ke Yao et al.   Stem Cell Research

Comparative Epigenomic Annotation of Regulatory DNA

(2012) Shu Xiao et al.   CELL

The Transcriptional and Epigenomic Foundations of Ground State Pluripotency

(2012) Hendrik Marks et al.   CELL

Signaling Network Crosstalk in Human Pluripotent Cells: A Smad2/3-Regulated Switch that Controls the Balance between Self-Renewal and Differentiation

(2012) Amar M. Singh et al.   Cell Stem Cell

The roles of FGF and MAP kinase signaling in the segregation of the epiblast and hypoblast cell lineages in bovine and human embryos

(2012) E. W. Kuijk et al.   DEVELOPMENT

X-chromosome inactivation in monkey embryos and pluripotent stem cells

(2012) Masahito Tachibana et al.   DEVELOPMENTAL BIOLOGY

Developmental Milestones Punctuate Gene Expression in the Caenorhabditis Embryo

(2012) Michal Levin et al.   DEVELOPMENTAL CELL

A Phylotypic Stage for All Animals?

(2012) Michael K. Richardson   DEVELOPMENTAL CELL

Dynamics of enhancer chromatin signatures mark the transition from pluripotency to cell specification during embryogenesis

(2012) O. Bogdanovic et al.   GENOME RESEARCH

Human trophectoderm cells are not yet committed

(2012) C. De Paepe et al.   HUMAN REPRODUCTION

Active DNA demethylation in mammalian preimplantation embryos: new insights and new perspectives

(2012) J.-Y. Ma et al.   MOLECULAR HUMAN REPRODUCTION

A transcriptomic hourglass in plant embryogenesis

(2012) Marcel Quint et al.   NATURE

Cell Lineage Specific Distribution of H3K27 Trimethylation Accumulation in an In Vitro Model for Human Implantation

(2012) Gijs Teklenburg et al.   PLoS One

Cross-Species Genome Wide Expression Analysis during Pluripotent Cell Determination in Mouse and Rat Preimplantation Embryos

(2012) Elisa A. Casanova et al.   PLoS One

Pluripotent cells in farm animals: state of the art and future perspectives

(2012) Monika Nowak-Imialek et al.   REPRODUCTION FERTILITY AND DEVELOPMENT

Why is it so Difficult to Derive Pluripotent Stem Cells in Domestic Ungulates?

(2012) F Gandolfi et al.   REPRODUCTION IN DOMESTIC ANIMALS

Wnt/ -Catenin Signaling Regulates Telomerase in Stem Cells and Cancer Cells

(2012) K. Hoffmeyer et al.   SCIENCE

The Combination of Inhibitors of FGF/MEK/Erk and GSK3β Signaling Increases the Number of OCT3/4- and NANOG-Positive Cells in the Human Inner Cell Mass, But Does Not Improve Stem Cell Derivation

(2012) Margot Van der Jeught et al.   STEM CELLS AND DEVELOPMENT

The evolution of early animal embryos: conservation or divergence?

(2012) Alex T. Kalinka et al.   TRENDS IN ECOLOGY & EVOLUTION

The heterogeneity and dynamic equilibrium of rat embryonic stem cells

(2011) Yan Shen et al.   CELL RESEARCH

Differential plasticity of epiblast and primitive endoderm precursors within the ICM of the early mouse embryo

(2011) J. B. Grabarek et al.   DEVELOPMENT

Reprogramming capacity of Nanog is functionally conserved in vertebrates and resides in a unique homeodomain

(2011) T. W. Theunissen et al.   DEVELOPMENT

Human hypoblast formation is not dependent on FGF signalling

(2011) Mila Roode et al.   DEVELOPMENTAL BIOLOGY

Trophectoderm Lineage Determination in Cattle

(2011) Debra K. Berg et al.   DEVELOPMENTAL CELL

Eutherian mammals use diverse strategies to initiate X-chromosome inactivation during development

(2011) Ikuhiro Okamoto et al.   NATURE

Comparative transcriptome analysis reveals vertebrate phylotypic period during organogenesis

(2011) Naoki Irie et al.   Nature Communications

Species-Specific Telomere Length Differences Between Blastocyst Cell Compartments and Ectopic Telomere Extension in Early Bovine Embryos by Human Telomerase Reverse Transcriptase

(2010) K. Iqbal et al.   BIOLOGY OF REPRODUCTION

Different Flavors of Pluripotency, Molecular Mechanisms, and Practical Implications

(2010) Christa Buecker et al.   Cell Stem Cell

FGF signal-dependent segregation of primitive endoderm and epiblast in the mouse blastocyst

(2010) Y. Yamanaka et al.   DEVELOPMENT

Sox17 promotes differentiation in mouse embryonic stem cells by directly regulating extraembryonic gene expression and indirectly antagonizing self-renewal

(2010) K. K. Niakan et al.   GENES & DEVELOPMENT

Rewirable gene regulatory networks in the preimplantation embryonic development of three mammalian species

(2010) D. Xie et al.   GENOME RESEARCH

The different shades of mammalian pluripotent stem cells

(2010) E. W. Kuijk et al.   HUMAN REPRODUCTION UPDATE

FGF-2 modulates Wnt signaling in undifferentiated hESC and iPS cells through activated PI3-K/GSK3β signaling

(2010) Vanessa M.Y. Ding et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Regulation of H3K27me3 and H3K4me3 during early porcine embryonic development

(2010) Yu Gao et al.   MOLECULAR REPRODUCTION AND DEVELOPMENT

Gene expression divergence recapitulates the developmental hourglass model

(2010) Alex T. Kalinka et al.   NATURE

A phylogenetically based transcriptome age index mirrors ontogenetic divergence patterns

(2010) Tomislav Domazet-Lošo et al.   NATURE

Widespread transcription at neuronal activity-regulated enhancers

(2010) Tae-Kyung Kim et al.   NATURE

Transposable elements have rewired the core regulatory network of human embryonic stem cells

(2010) Galih Kunarso et al.   NATURE GENETICS

Evolution of the mammalian embryonic pluripotency gene regulatory network

(2010) B. Fernandez-Tresguerres et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Distinct histone modifications in stem cell lines and tissue lineages from the early mouse embryo

(2010) P. J. Rugg-Gunn et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Histone H3K27ac separates active from poised enhancers and predicts developmental state

(2010) M. P. Creyghton et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Five-Vertebrate ChIP-seq Reveals the Evolutionary Dynamics of Transcription Factor Binding

(2010) D. Schmidt et al.   SCIENCE

Functional Heterogeneity of Embryonic Stem Cells Revealed through Translational Amplification of an Early Endodermal Transcript

(2010) Maurice A. Canham et al.   PLOS BIOLOGY

Promoter analysis of the rabbit POU5F1 gene and its expression in preimplantation stage embryos

(2009) Julianna Kobolak et al.   BMC MOLECULAR BIOLOGY

Optimal Timing of Inner Cell Mass Isolation Increases the Efficiency of Human Embryonic Stem Cell Derivation and Allows Generation of Sibling Cell Lines

(2009) Alice E. Chen et al.   Cell Stem Cell

Phosphorylation Dynamics during Early Differentiation of Human Embryonic Stem Cells

(2009) Dennis Van Hoof et al.   Cell Stem Cell

Naive and Primed Pluripotent States

(2009) Jennifer Nichols et al.   Cell Stem Cell

Suppression of Erk signalling promotes ground state pluripotency in the mouse embryo

(2009) J. Nichols et al.   DEVELOPMENT

The Hippo Signaling Pathway Components Lats and Yap Pattern Tead4 Activity to Distinguish Mouse Trophectoderm from Inner Cell Mass

(2009) Noriyuki Nishioka et al.   DEVELOPMENTAL CELL

Telomerase modulates Wnt signalling by association with target gene chromatin

(2009) Jae-Il Park et al.   NATURE

Validated germline-competent embryonic stem cell lines from nonobese diabetic mice

(2009) Jennifer Nichols et al.   NATURE MEDICINE

A Review of Implantation and Early Placentation in the Mare

(2009) W.R. Allen et al.   PLACENTA

From Zygote to Implantation: Morphological and Molecular Dynamics during Embryo Development in the Pig

(2009) O Oestrup et al.   REPRODUCTION IN DOMESTIC ANIMALS

Identification of Pou5f1, Sox2, and Nanog downstream target genes with statistical confidence by applying a novel algorithm to time course microarray and genome-wide chromatin immunoprecipitation data

(2008) Alexei A Sharov et al.   BMC GENOMICS

Capture of Authentic Embryonic Stem Cells from Rat Blastocysts

(2008) Mia Buehr et al.   CELL

Integration of External Signaling Pathways with the Core Transcriptional Network in Embryonic Stem Cells

(2008) Xi Chen et al.   CELL

Dynamic Equilibrium and Heterogeneity of Mouse Pluripotent Stem Cells with Distinct Functional and Epigenetic States

(2008) Katsuhiko Hayashi et al.   Cell Stem Cell

Identification and characterization of subpopulations in undifferentiated ES cell culture

(2008) Y. Toyooka et al.   DEVELOPMENT

Blastomeres of the mouse embryo lose totipotency after the fifth cleavage division: Expression of Cdx2 and Oct4 and developmental potential of inner and outer blastomeres of 16- and 32-cell embryos

(2008) Aneta Suwińska et al.   DEVELOPMENTAL BIOLOGY

Differences in early lineage segregation between mammals

(2008) Ewart W. Kuijk et al.   DEVELOPMENTAL DYNAMICS

Markers that define stemness in ESC are unable to identify the totipotent cells in human preimplantation embryos

(2008) G. Cauffman et al.   HUMAN REPRODUCTION

The ground state of embryonic stem cell self-renewal

(2008) Qi-Long Ying et al.   NATURE

Polycomb gene expression and histone H3 lysine 27 trimethylation changes during bovine preimplantation development

(2008) Pablo J Ross et al.   REPRODUCTION

Enhanced cardiomyogenesis of human embryonic stem cells by a small molecular inhibitor of p38 MAPK

(2007) Ralph Graichen et al.   DIFFERENTIATION