Hypoxia and HIF-1α promote lytic de novo KSHV infection

Hypoxia and hypoxia‐inducible factors in Kaposi sarcoma‐associated herpesvirus infection and disease pathogenesis

(2023) David A. Davis et al.   JOURNAL OF MEDICAL VIROLOGY

Evidence for Multiple Subpopulations of Herpesvirus-Latently Infected Cells

(2022) Justin T. Landis et al.   mBio

In-Depth Temporal Transcriptome Profiling of an Alphaherpesvirus Using Nanopore Sequencing

(2022) Dóra Tombácz et al.   Viruses-Basel

Single-cell analysis of Kaposi’s sarcoma-associated herpesvirus infection in three-dimensional air-liquid interface culture model

(2022) Kyle L. Jung et al.   PLoS Pathogens

PRC1-independent binding and activity of RYBP on the KSHV genome during de novo infection

(2022) See-Chi Lee et al.   PLoS Pathogens

Hypoxia and viral infectious diseases

(2021) Richard Huang et al.   JCI Insight

KSHV-encoded vCyclin can modulate HIF1α levels to promote DNA replication in hypoxia

(2021) Rajnish Kumar Singh et al.   eLife

Kaposi’s sarcoma herpesvirus activates the hypoxia response to usurp HIF2α-dependent translation initiation for replication and oncogenesis

(2021) Omayra Méndez-Solís et al.   Cell Reports

Epigenetic control in Kaposi sarcoma-associated herpesvirus infection and associated disease

(2020) Jacqueline Fröhlich et al.   Seminars in Immunopathology

Kaposi's sarcoma-associated herpesvirus/human herpesvirus 8 associated lymphoproliferative disorders

(2019) Eric Oksenhendler et al.   BLOOD

KSHV-encoded LANA protects the cellular replication machinery from hypoxia induced degradation

(2019) Rajnish Kumar Singh et al.   PLoS Pathogens

A role of hypoxia-inducible factor 1 alpha in Murine Gammaherpesvirus 68 (MHV68) lytic replication and reactivation from latency

(2019) Darlah M. López-Rodríguez et al.   PLoS Pathogens

The use of cobalt chloride as a chemical hypoxia model

(2018) Jorge Muñoz-Sánchez et al.   JOURNAL OF APPLIED TOXICOLOGY

Inhibition of the lytic cycle of Kaposi's sarcoma-associated herpesvirus by cohesin factors following de novo infection

(2017) Zsolt Toth et al.   VIROLOGY

Hypoxia-inducible factor-1 alpha as a therapeutic target for primary effusion lymphoma

(2017) Prabha Shrestha et al.   PLoS Pathogens

RNA Sequencing Reveals that Kaposi Sarcoma-Associated Herpesvirus Infection Mimics Hypoxia Gene Expression Signature

(2017) Coralie Viollet et al.   PLoS Pathogens

Reactivation and Lytic Replication of Kaposi’s Sarcoma-Associated Herpesvirus: An Update

(2017) Kawalpreet K. Aneja et al.   Frontiers in Microbiology

Oxygen Levels and Immunological Studies

(2017) Lauren A. Zenewicz   Frontiers in Immunology

LANA-Mediated Recruitment of Host Polycomb Repressive Complexes onto the KSHV Genome during De Novo Infection

(2016) Zsolt Toth et al.   PLoS Pathogens

Regulation of Hypoxia-Inducible Factor-1a by Reactive Oxygen Species : New Developments in an Old Debate

(2015) Shahrzad Movafagh et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Chromatinization of the KSHV Genome During the KSHV Life Cycle

(2015) Timsy Uppal et al.   Cancers

Short-Chain Fatty Acids from Periodontal Pathogens Suppress Histone Deacetylases, EZH2, and SUV39H1 To Promote Kaposi's Sarcoma-Associated Herpesvirus Replication

(2014) X. Yu et al.   JOURNAL OF VIROLOGY

Activation of Kaposi's Sarcoma-Associated Herpesvirus (KSHV) by Inhibitors of Class III Histone Deacetylases: Identification of Sirtuin 1 as a Regulator of the KSHV Life Cycle

(2014) Q. Li et al.   JOURNAL OF VIROLOGY

Negative Elongation Factor-Mediated Suppression of RNA Polymerase II Elongation of Kaposi's Sarcoma-Associated Herpesvirus Lytic Gene Expression

(2012) Zsolt Toth et al.   JOURNAL OF VIROLOGY

The Kaposi's Sarcoma-Associated Herpesvirus ORF34 Protein Binds to HIF-1  and Causes Its Degradation via the Proteasome Pathway

(2012) M. Haque et al.   JOURNAL OF VIROLOGY

Construction and Manipulation of a New Kaposi's Sarcoma-Associated Herpesvirus Bacterial Artificial Chromosome Clone

(2012) Kevin F. Brulois et al.   JOURNAL OF VIROLOGY

Clinical Manifestations of Kaposi Sarcoma Herpesvirus Lytic Activation: Multicentric Castleman Disease (KSHV–MCD) and the KSHV Inflammatory Cytokine Syndrome

(2012) Mark N. Polizzotto et al.   Frontiers in Microbiology

Why is the partial oxygen pressure of human tissues a crucial parameter? Small molecules and hypoxia

(2011) Aude Carreau et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Kaposi's Sarcoma-Associated Herpesvirus Latency-Associated Nuclear Antigen Induction by Hypoxia and Hypoxia-Inducible Factors

(2011) R. P. Veeranna et al.   JOURNAL OF VIROLOGY

Amplification of the Angiogenic Signal through the Activation of the TSC/mTOR/HIF Axis by the KSHV vGPCR in Kaposi's Sarcoma

(2011) Bruno C. Jham et al.   PLoS One

Epigenetic Analysis of KSHV Latent and Lytic Genomes

(2010) Zsolt Toth et al.   PLoS Pathogens

Kaposi's Sarcoma-Associated Herpesvirus Viral IFN Regulatory Factor 3 Stabilizes Hypoxia-Inducible Factor-1  to Induce Vascular Endothelial Growth Factor Expression

(2008) Y. C. Shin et al.   CANCER RESEARCH

Reactivation of Kaposi's sarcoma-associated herpesvirus from latency requires MEK/ERK, JNK and p38 multiple mitogen-activated protein kinase pathways

(2007) Jianping Xie et al.   VIROLOGY