Shotgun Proteomic-Based Approach with a Q-Exactive Hybrid Quadrupole-Orbitrap High-Resolution Mass Spectrometer for Protein Adductomics on a 3D Human Brain Tumor Neurospheroid Culture Model: The Identification of Adduct Formation in Calmodulin-Dependent Protein Kinase-2 and Annexin-A1 Induced by Pesticide Mixture

Differential Proteome Profiling Analysis under Pesticide Stress by the Use of a Nano-UHPLC-MS/MS Untargeted Proteomic-Based Approach on a 3D-Developed Neurospheroid Model: Identification of Protein Interactions, Prognostic Biomarkers, and Potential Therapeutic Targets in Human IDH Mutant High-Grade Gliomas

(2023) Kaouthar Louati et al.   JOURNAL OF PROTEOME RESEARCH

A Common Feature of Pesticides: Oxidative Stress—The Role of Oxidative Stress in Pesticide-Induced Toxicity

(2022) Rasheed O. Sule et al.   Oxidative Medicine and Cellular Longevity

Annexin‐1 is an oncogene in glioblastoma and causes tumour immune escape through the indirect upregulation of interleukin‐8

(2022) Rui Chen et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

In Vitro Assessment of Pesticides Toxicity and Data Correlation with Pesticides Physicochemical Properties for Prediction of Toxicity in Gastrointestinal and Skin Contact Exposure

(2022) Amélia M. Silva et al.   Toxics

The dysregulated expression and functional effect of CaMK2 in cancer

(2021) Qi He et al.   Cancer Cell International

Identification of pesticides exposure biomarkers for residents living close to vineyards in France

(2021) Clémentine Dereumeaux et al.   ENVIRONMENT INTERNATIONAL

Calcium-/Calmodulin-Dependent Protein Kinase II (CaMKII) Inhibition Induces Learning and Memory Impairment and Apoptosis

(2021) Jialu Wang et al.   Oxidative Medicine and Cellular Longevity

The Role of Calmodulin in Tumor Cell Migration, Invasiveness, and Metastasis

(2020) Antonio Villalobo et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Joint toxicity of two phytosanitary molecules, lambda-cyhalothrin and acetamiprid, on African catfish (Clarias gariepinus) juveniles

(2020) Mahugnon A. B. Houndji et al.   JOURNAL OF ENVIRONMENTAL SCIENCE AND HEALTH PART B-PESTICIDES FOOD CONTAMINANTS AND AGRICULTURAL WASTES

MaxQuant Software for Ion Mobility Enhanced Shotgun Proteomics

(2020) Nikita Prianichnikov et al.   MOLECULAR & CELLULAR PROTEOMICS

Low doses of the neonicotinoid insecticide imidacloprid induce ROS triggering neurological and metabolic impairments inDrosophila

(2020) Felipe Martelli et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Effects of low-level imidacloprid oral exposure on cholinesterase activity, oxidative stress responses, and primary DNA damage in the blood and brain of male Wistar rats

(2020) Anja Katić et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Diabetic Hyperglycemia Regulates Potassium Channels and Arrhythmias in the Heart via Autonomous CaMKII Activation by O-Linked Glycosylation

(2019) Bence Hegyi et al.   BIOPHYSICAL JOURNAL

Lambda-cyhalothrin exposure alters purine nucleotide hydrolysis and nucleotidase gene expression pattern in platelets and liver of rats

(2019) Bakhta Aouey et al.   CHEMICO-BIOLOGICAL INTERACTIONS

The effect of chronic vitamin deficiency and long term very low dose exposure to 6 pesticides mixture on neurological outcomes – A real-life risk simulation approach

(2019) Aristidis Tsatsakis et al.   TOXICOLOGY LETTERS

Structural Insights into the Regulation of Ca2+/Calmodulin-Dependent Protein Kinase II (CaMKII)

(2019) Moitrayee Bhattacharyya et al.   Cold Spring Harbor Perspectives in Biology

A Patient-Derived Glioblastoma Organoid Model and Biobank Recapitulates Inter- and Intra-tumoral Heterogeneity

(2019) Fadi Jacob et al.   CELL

Nonoccupational Exposure of Agricultural Area Residents to Pesticides: Pesticide Accumulation and Evaluation of Genotoxicity

(2018) Zeynep Banu Doğanlar et al.   ARCHIVES OF ENVIRONMENTAL CONTAMINATION AND TOXICOLOGY

Annexin A1: Uncovering the Many Talents of an Old Protein

(2018) et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Genotoxic and oxidative damage in the freshwater teleost Prochilodus lineatus exposed to the insecticides lambda-cyhalothrin and imidacloprid alone and in combination

(2018) Tiago Tomiama Alvim et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

Pesticide residues in European agricultural soils – A hidden reality unfolded

(2018) Vera Silva et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Combined toxicity of imidacloprid and three insecticides to the earthworm, Eisenia fetida (Annelida, Oligochaeta)

(2017) Tao Cang et al.   ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH

Inhibition of Human Drug Transporter Activities by the Pyrethroid Pesticides Allethrin and Tetramethrin

(2017) Lisa Chedik et al.   PLoS One

Long-term exposure of rabbits to imidaclorpid as quantified in blood induces genotoxic effect

(2016) Polychronis D. Stivaktakis et al.   CHEMOSPHERE

Study of commonly used organophosphate pesticides that induced oxidative stress and apoptosis in peripheral blood lymphocytes of rats

(2016) A Ojha et al.   HUMAN & EXPERIMENTAL TOXICOLOGY

Occupational pesticide exposure and adverse health effects at the clinical, hematological and biochemical level

(2016) Carmen R. García-García et al.   LIFE SCIENCES

Exposome-Explorer: a manually-curated database on biomarkers of exposure to dietary and environmental factors

(2016) Vanessa Neveu et al.   NUCLEIC ACIDS RESEARCH

Identification of protein adduction using mass spectrometry: Protein adducts as biomarkers and predictors of toxicity mechanisms

(2016) Xiangkun Yang et al.   RAPID COMMUNICATIONS IN MASS SPECTROMETRY

3D tumor spheroid models for in vitro therapeutic screening: a systematic approach to enhance the biological relevance of data obtained

(2016) Michele Zanoni et al.   Scientific Reports

Toxicity of mixtures of λ-cyhalothrin, imidacloprid and cadmium on the earthworm Eisenia fetida by combination index (CI)-isobologram method

(2015) Yanhua Wang et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

Biomonitoring of agricultural workers exposed to pesticide mixtures in Guerrero state, Mexico, with comet assay and micronucleus test

(2015) Yolanda Carbajal-López et al.   ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH

Neurodevelopmental consequences of gestational and lactational exposure to pyrethroids in rats

(2015) Farah Syed et al.   ENVIRONMENTAL TOXICOLOGY

Redox proteomics identification of specifically carbonylated proteins in the hippocampi of triple transgenic Alzheimer's disease mice at its earliest pathological stage

(2015) Liming Shen et al.   Journal of Proteomics

Pyrethroids and Nectar Toxins Have Subtle Effects on the Motor Function, Grooming and Wing Fanning Behaviour of Honeybees (Apis mellifera)

(2015) Caitlin J. Oliver et al.   PLoS One

The emerging role of CaMKII in cancer

(2015) Yan-yang Wang et al.   Oncotarget

Low doses of neonicotinoid pesticides in food rewards impair short-term olfactory memory in foraging-age honeybees

(2015) Geraldine A. Wright et al.   Scientific Reports

Determination of protein carbonyls in plasma, cell extracts, tissue homogenates, isolated proteins: Focus on sample preparation and derivatization conditions

(2015) Daniela Weber et al.   Redox Biology

Calmodulin antagonists induce cell cycle arrest and apoptosis in vitro and inhibit tumor growth in vivo in human multiple myeloma

(2014) Shigeyuki Yokokura et al.   BMC CANCER

Health risk assessment of organochlorine pesticide exposure through dietary intake of vegetables grown in the periurban sites of Delhi, India

(2014) Sapna Chourasiya et al.   ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH

Assessment of health risk from organochlorine pesticides residues in high-fat spreadable foods produced in Poland

(2014) Agata Witczak et al.   JOURNAL OF ENVIRONMENTAL SCIENCE AND HEALTH PART B-PESTICIDES FOOD CONTAMINANTS AND AGRICULTURAL WASTES

Evaluation of imidacloprid-induced neurotoxicity in male rats: A protective effect of curcumin

(2014) Milindmitra Lonare et al.   NEUROCHEMISTRY INTERNATIONAL

Evaluation of oxidative stress in long-term exposed rabbits to subtoxic levels of imidacloprid

(2014) Polychronis Stivaktakis et al.   TOXICOLOGY LETTERS

UniNovo: a universal tool for de novo peptide sequencing

(2013) Kyowon Jeong et al.   BIOINFORMATICS

Pesticides and human chronic diseases: Evidences, mechanisms, and perspectives

(2013) Sara Mostafalou et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Advances in establishment and analysis of three-dimensional tumor spheroid-based functional assays for target validation and drug evaluation

(2012) Maria Vinci et al.   BMC BIOLOGY

Proteomics of a new esophageal cancer cell line established from Persian patient

(2012) Mehdi Moghanibashi et al.   GENE

The exposome: from concept to utility

(2012) Christopher Paul Wild   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

Upregulation of Hsp90-beta and annexin A1 correlates with poor survival and lymphatic metastasis in lung cancer patients

(2012) Rong Biaoxue et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Protein adducts as biomarkers of exposure to organophosphorus compounds

(2012) Judit Marsillach et al.   TOXICOLOGY

Identification of annexin A1 as a proinvasive and prognostic factor for lung adenocarcinoma

(2011) Ying-Fu Liu et al.   CLINICAL & EXPERIMENTAL METASTASIS

Proteomics for identifying mechanisms and biomarkers of drug resistance in cancer

(2011) Xin-Hui Li et al.   Journal of Proteomics

Proteome analysis of the effects of sorafenib on human hepatocellular carcinoma cell line HepG2

(2011) Aili Suo et al.   MEDICAL ONCOLOGY

Effect of Endocrine Disruptor Pesticides: A Review

(2011) Wissem Mnif et al.   International Journal of Environmental Research and Public Health

Persistent organochlorine pesticide residues in animal feed

(2010) Subir Kumar Nag et al.   ENVIRONMENTAL MONITORING AND ASSESSMENT

Isolation and characterization of tumor stem-like cells from human meningiomas

(2010) Dueng-Yuan Hueng et al.   JOURNAL OF NEURO-ONCOLOGY

An Update of Cancer Incidence in the Agricultural Health Study

(2010) Stella Koutros et al.   JOURNAL OF OCCUPATIONAL AND ENVIRONMENTAL MEDICINE

Proteomic Identification of Carbonylated Proteins and Their Oxidation Sites

(2010) Ashraf G. Madian et al.   JOURNAL OF PROTEOME RESEARCH

Assessing Hormone Receptor Activities of Pyrethroid Insecticides and Their Metabolites in Reporter Gene Assays

(2010) Guizhen Du et al.   TOXICOLOGICAL SCIENCES

Oxidative modifications of glyceraldehyde-3-phosphate dehydrogenase play a key role in its multiple cellular functions

(2009) Na Rae Hwang et al.   BIOCHEMICAL JOURNAL

Isolation of tumour stem-like cells from benign tumours

(2009) Q Xu et al.   BRITISH JOURNAL OF CANCER

Spheroid-based drug screen: considerations and practical approach

(2009) Juergen Friedrich et al.   Nature Protocols

Highly tumorigenic lung cancer CD133+ cells display stem-like features and are spared by cisplatin treatment

(2009) G. Bertolini et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Differential expression proteomics of human colorectal cancer based on a syngeneic cellular model for the progression of adenoma to carcinoma

(2009) Udo Roth et al.   PROTEOMICS

Oxidative stress induces gastric epithelial permeability through claudin-3

(2008) Kayo Hashimoto et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Proteomic studies of B16 lines: Involvement of Annexin A1 in melanoma dissemination

(2008) Fabien Rondepierre et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Cancer stem cells in multiple myeloma

(2008) Nilanjan Ghosh et al.   CANCER LETTERS

Identification of Novel Nasopharyngeal Carcinoma Biomarkers by Laser Capture Microdissection and Proteomic Analysis

(2008) A.-L. Cheng et al.   CLINICAL CANCER RESEARCH

Oxidative stress induced by lambda-cyhalothrin (LTC) in rat erythrocytes and brain: Attenuation by vitamin C

(2008) Hamadi Fetoui et al.   ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY

Upregulation of Annexin A1 Expression by Butyrate in Human Colon Adenocarcinoma Cells: Role of p53, NF-Y, and p38 Mitogen-Activated Protein Kinase

(2008) E. Lecona et al.   MOLECULAR AND CELLULAR BIOLOGY

Identification of cells initiating human melanomas

(2008) Tobias Schatton et al.   NATURE