Design, synthesis, characterization, and anti-tubercular activity of novel ethyl-3-benzoyl-6, 8-difluoroindolizine-1-carboxylate analogues: Molecular target identification and molecular docking studies

Efficacy of bedaquiline in the treatment of drug-resistant tuberculosis: a systematic review and meta-analysis

(2021) Ming-Gui Wang et al.   BMC INFECTIOUS DISEASES

Crystallography, Molecular Modeling, and COX-2 Inhibition Studies on Indolizine Derivatives

(2021) Katharigatta N. Venugopala et al.   MOLECULES

Introduction: Novel insights into TB research and drug discovery

(2020) Gerhard Grüber   PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY

Multitargeting Compounds: A Promising Strategy to Overcome Multi-Drug Resistant Tuberculosis

(2020) Giovanni Stelitano et al.   MOLECULES

In silico Design and Synthesis of Tetrahydropyrimidinones and Tetrahydropyrimidinethiones as Potential Thymidylate Kinase Inhibitors Exerting Anti-TB Activity Against Mycobacterium tuberculosis

(2020) Katharigatta N Venugopala et al.   Drug Design Development and Therapy

Inhibitory activities of indolizine derivatives: a patent review

(2020) Kamal M. Dawood et al.   EXPERT OPINION ON THERAPEUTIC PATENTS

Current advances in the clinical development of anti-tubercular agents

(2020) Samanvai Reddy Tetali et al.   TUBERCULOSIS

Anti-tubercular Potency and Computationallyassessed Drug-likeness and Toxicology of Diversely Substituted Indolizines

(2019) Katharigatta N Venugopala et al.   Indian Journal of Pharmaceutical Education and Research

Computational, crystallographic studies, cytotoxicity and anti-tubercular activity of substituted 7-methoxy-indolizine analogues

(2019) Katharigatta Narayanaswamy Venugopala et al.   PLoS One

Pretomanid: First Approval

(2019) Susan J. Keam   DRUGS

Design, synthesis, and structural elucidation of novel NmeNANAS inhibitors for the treatment of meningococcal infection

(2019) Osama I. Alwassil et al.   PLoS One

Novel Series of Methyl 3-(Substituted Benzoyl)-7-Substituted-2-Phenylindolizine-1-Carboxylates as Promising Anti-Inflammatory Agents: Molecular Modeling Studies

(2019) Venugopala et al.   Biomolecules

Efficient Synthesis and Characterization of Novel Substituted 3-Benzoylindolizine Analogues via the Cyclization of Aromatic Cycloimmoniumylides with Electrondeficient Alkenes

(2018) Katharigatta N. Venugopala et al.   CURRENT ORGANIC SYNTHESIS

Benzothiazole analogs as potential anti-TB agents: computational input and molecular dynamics

(2018) Katharigatta N. Venugopala et al.   JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS

One-pot microwave assisted synthesis and structural elucidation of novel ethyl 3-substituted-7-methylindolizine-1-carboxylates with larvicidal activity against Anopheles arabiensis

(2018) Sandeep Chandrashekharappa et al.   JOURNAL OF MOLECULAR STRUCTURE

Efficient synthesis and characterization of novel indolizines: exploration of in vitro COX-2 inhibitory activity and molecular modelling studies

(2018) Sandeep Chandrashekharappa et al.   NEW JOURNAL OF CHEMISTRY

Mechanisms of resistance to delamanid, a drug for Mycobacterium tuberculosis

(2018) Mamoru Fujiwara et al.   TUBERCULOSIS

Molecular Targets Related Drug Resistance Mechanisms in MDR-, XDR-, and TDR-Mycobacterium tuberculosis Strains

(2018) H. M. Adnan Hameed et al.   Frontiers in Cellular and Infection Microbiology

Design and Synthesis of Novel Indolizine Analogues as COX-2 Inhibitors: Computational Perspective and in vitro Screening

(2017) Chandrashekharappa Sandeep et al.   Indian Journal of Pharmaceutical Education and Research

Molecular modeling studies and anti-TB activity of trisubstituted indolizine analogues; molecular docking and dynamic inputs

(2017) Mohammed A. Khedr et al.   JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS

Antimycobacterial activity of nitrogen heterocycles derivatives: 7-(pyridine-4-yl)-indolizine derivatives. Part VII8–12

(2017) Anda-Mihaela Olaru et al.   JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

Prevalence and Molecular Characterization of Second-Line Drugs Resistance among Multidrug-Resistant Mycobacterium tuberculosis Isolates in Southwest of China

(2017) Y. Hu et al.   Biomed Research International

Synthesis and Characterization of Ethyl 7-Acetyl-2-substituted 3-(substituted benzoyl)indolizine-1-carboxylates for in vitro Anticancer Activity

(2016) C. Sandeep et al.   ASIAN JOURNAL OF CHEMISTRY

Greener synthesis of indolizine analogues using water as a base and solvent: study for larvicidal activity againstAnopheles arabiensis

(2016) Chandrashekharappa Sandeep et al.   Chemical Biology & Drug Design

New indolizines with phenanthroline skeleton: Synthesis, structure, antimycobacterial and anticancer evaluation

(2015) Ramona Danac et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Antimycobacterial activity of natural products and synthetic agents: Pyrrolodiquinolines and vermelhotin as anti-tubercular leads against clinical multidrug resistant isolates of Mycobacterium tuberculosis

(2015) Dakshina U. Ganihigama et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Novel Insights into the Mechanism of Inhibition of MmpL3, a Target of Multiple Pharmacophores in Mycobacterium tuberculosis

(2014) Wei Li et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Bedaquiline: a review of human pharmacokinetics and drug-drug interactions

(2014) R. P. G. van Heeswijk et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Antimycobacterial activity of nitrogen heterocycles derivatives: Bipyridine derivatives. Part III [13,14]

(2013) Ramona Danac et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Azaindoles: Noncovalent DprE1 Inhibitors from Scaffold Morphing Efforts, Kill Mycobacterium tuberculosis and Are Efficacious in Vivo

(2013) Pravin S. Shirude et al.   JOURNAL OF MEDICINAL CHEMISTRY

Efficient synthesis of indolizines and new imidazo[1,2-a]pyridines via the expected cyclization of aromatic cycloimmonium ylides with electron deficient alkynes and ethyl cyanoformate

(2013) C. Sandeep et al.   TETRAHEDRON LETTERS

Discovery and development of SQ109: a new antitubercular drug with a novel mechanism of action

(2012) Katherine A Sacksteder et al.   Future Microbiology

Amberlite–IRA-402 (OH) ion exchange resin mediated synthesis of indolizines, pyrrolo [1,2-a] quinolines and isoquinolines: Antibacterial and antifungal evaluation of the products

(2011) Abhijit Hazra et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Recent progress in synthesis and bioactivity studies of indolizines

(2011) Girija S. Singh et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Early treatment outcomes and HIV status of patients with extensively drug-resistant tuberculosis in South Africa: a retrospective cohort study

(2010) Keertan Dheda et al.   LANCET