Discovery and development of SQ109: a new antitubercular drug with a novel mechanism of action
Published 2012 View Full Article
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Title
Discovery and development of SQ109: a new antitubercular drug with a novel mechanism of action
Authors
Keywords
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Journal
Future Microbiology
Volume 7, Issue 7, Pages 823-837
Publisher
Future Medicine Ltd
Online
2012-07-24
DOI
10.2217/fmb.12.56
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- (2012) Anna E Grzegorzewicz et al. Nature Chemical Biology
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- (2012) Robert S. Wallis et al. PLoS One
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- Tuberculosis drugs: new candidates and how to find more
- (2011) Claudia Sala et al. Future Microbiology
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- Ansiedade e depressão em pacientes com asma: impacto no controle da asma
- (2011) Aline Arlindo Vieira et al. Jornal Brasileiro de Pneumologia
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- (2010) Armand Van Deun et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- Early Bactericidal Activity and Pharmacokinetics of PA-824 in Smear-Positive Tuberculosis Patients
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- Drugs in Development for Tuberculosis
- (2010) Ann M. Ginsberg DRUGS
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- Multidrug-resistant and extensively drug-resistant tuberculosis: a threat to global control of tuberculosis
- (2010) Neel R Gandhi et al. LANCET
- New Antituberculous Drugs in Development
- (2010) Umesh G. Lalloo et al. Current HIV/AIDS Reports
- The Arabinosyltransferase EmbC Is Inhibited by Ethambutol in Mycobacterium tuberculosis
- (2009) R. Goude et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Synthesis of novel [1,2]-diamines with antituberculosis activity
- (2009) Qingyi Meng et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Synthesis and evaluation of carbamate prodrugs of SQ109 as antituberculosis agents
- (2009) Qingyi Meng et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
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- (2009) G. B. Migliori et al. EUROPEAN RESPIRATORY JOURNAL
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- (2009) Evan W Orenstein et al. LANCET INFECTIOUS DISEASES
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