A half-century of research on tuberculosis: Successes and challenges
Published 2023 View Full Article
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Title
A half-century of research on tuberculosis: Successes and challenges
Authors
Keywords
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Journal
JOURNAL OF EXPERIMENTAL MEDICINE
Volume 220, Issue 9, Pages -
Publisher
Rockefeller University Press
Online
2023-07-22
DOI
10.1084/jem.20230859
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Note: Only part of the references are listed.- Mycobacterium smegmatis: The Vanguard of Mycobacterial Research
- (2023) Ian L. Sparks et al. JOURNAL OF BACTERIOLOGY
- Treatment Strategy for Rifampin-Susceptible Tuberculosis
- (2023) Nicholas I. Paton et al. NEW ENGLAND JOURNAL OF MEDICINE
- US public investment in development of mRNA covid-19 vaccines: retrospective cohort study
- (2023) Hussain S Lalani et al. BMJ-British Medical Journal
- Diagnostic yield of urine lipoarabinomannan and sputum tuberculosis tests in people living with HIV: a systematic review and meta-analysis of individual participant data
- (2023) Tobias Broger et al. Lancet Global Health
- IFN-γ independent markers of Mycobacterium tuberculosis exposure among male South African gold miners
- (2023) Leela R.L. Davies et al. EBioMedicine
- Global, regional, and national estimates of tuberculosis incidence and case detection among incarcerated individuals from 2000 to 2019: a systematic analysis
- (2023) Leonardo Martinez et al. Lancet Public Health
- The Tuberculous Granuloma and Preexisting Immunity
- (2022) Sara B. Cohen et al. Annual Review of Immunology
- The immunoregulatory landscape of human tuberculosis granulomas
- (2022) Erin F. McCaffrey et al. NATURE IMMUNOLOGY
- Host-pathogen genetic interactions underlie tuberculosis susceptibility in genetically diverse mice
- (2022) Clare M Smith et al. eLife
- Aerosolization of Mycobacterium tuberculosis by Tidal Breathing
- (2022) Ryan Dinkele et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- Multimodal profiling of lung granulomas in macaques reveals cellular correlates of tuberculosis control
- (2022) Hannah P. Gideon et al. IMMUNITY
- Diagnostic accuracy of WHO screening criteria to guide lateral-flow lipoarabinomannan testing among HIV-positive inpatients: A systematic review and individual participant data meta-analysis
- (2022) Ashar Dhana et al. JOURNAL OF INFECTION
- Anti-tuberculosis treatment strategies and drug development: challenges and priorities
- (2022) Véronique A. Dartois et al. NATURE REVIEWS MICROBIOLOGY
- A Direct Measure of Tuberculosis Incidence — Effect of Community Screening
- (2022) Guy B. Marks et al. NEW ENGLAND JOURNAL OF MEDICINE
- CRISPR detection of circulating cell-free Mycobacterium tuberculosis DNA in adults and children, including children with HIV: a molecular diagnostics study
- (2022) Zhen Huang et al. Lancet Microbe
- Programmable RNA-Guided Large DNA Transgenesis by CRISPR/Cas9 and Site-Specific Integrase Bxb1
- (2022) Vishnu Hosur et al. Frontiers in Bioengineering and Biotechnology
- From rare disorders of immunity to common determinants of infection: Following the mechanistic thread
- (2022) Jean-Laurent Casanova et al. CELL
- Bedaquiline–Pretomanid–Linezolid Regimens for Drug-Resistant Tuberculosis
- (2022) Francesca Conradie et al. NEW ENGLAND JOURNAL OF MEDICINE
- Infant BCG vaccination and risk of pulmonary and extrapulmonary tuberculosis throughout the life course: a systematic review and individual participant data meta-analysis
- (2022) Leonardo Martinez et al. Lancet Global Health
- Reconciling Mouse and Human Immunology at the Altar of Genetics
- (2022) Philippe Gros et al. Annual Review of Immunology
- The Struggle to End a Millennia-Long Pandemic: Novel Candidate and Repurposed Drugs for the Treatment of Tuberculosis
- (2022) Brett D. Edwards et al. DRUGS
- Anti-tuberculosis drug development via targeting the cell envelope of Mycobacterium tuberculosis
- (2022) Xinyue Xu et al. Frontiers in Microbiology
- Biomarker-guided tuberculosis preventive therapy (CORTIS): a randomised controlled trial
- (2021) Thomas J Scriba et al. LANCET INFECTIOUS DISEASES
- BCG-induced non-specific effects on heterologous infectious disease in Ugandan neonates: an investigator-blind randomised controlled trial
- (2021) Sarah Prentice et al. LANCET INFECTIOUS DISEASES
- Latent Tuberculosis: Two Centuries of Confusion
- (2021) Marcel A Behr et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- Synthesis and recycling of the mycobacterial cell envelope
- (2021) Katherine A Abrahams et al. CURRENT OPINION IN MICROBIOLOGY
- Four-Month Rifapentine Regimens with or without Moxifloxacin for Tuberculosis
- (2021) Susan E. Dorman et al. NEW ENGLAND JOURNAL OF MEDICINE
- Longitudinal Dynamics of a Blood Transcriptomic Signature of Tuberculosis
- (2021) Humphrey Mulenga et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- Micro–Computed Tomography Analysis of the Human Tuberculous Lung Reveals Remarkable Heterogeneity in Three-dimensional Granuloma Morphology
- (2021) Gordon Wells et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- Blood transcriptomics reveal the evolution and resolution of the immune response in tuberculosis
- (2021) Olivier Tabone et al. JOURNAL OF EXPERIMENTAL MEDICINE
- The cellular architecture of the antimicrobial response network in human leprosy granulomas
- (2021) Feiyang Ma et al. NATURE IMMUNOLOGY
- MTBVAC, a live TB vaccine poised to initiate efficacy trials 100 years after BCG
- (2021) Carlos Martín et al. VACCINE
- Vaccine Development Against Tuberculosis Over the Last 140 Years: Failure as Part of Success
- (2021) Stefan H. E. Kaufmann Frontiers in Microbiology
- Prevention of tuberculosis in macaques after intravenous BCG immunization
- (2020) Patricia A. Darrah et al. NATURE
- Concise whole blood transcriptional signatures for incipient tuberculosis: a systematic review and patient-level pooled meta-analysis
- (2020) Rishi K Gupta et al. Lancet Respiratory Medicine
- Mycobacterium tuberculosis Sulfolipid-1 Activates Nociceptive Neurons and Induces Cough
- (2020) Cody R. Ruhl et al. CELL
- Mouse transcriptome reveals potential signatures of protection and pathogenesis in human tuberculosis
- (2020) Lúcia Moreira-Teixeira et al. NATURE IMMUNOLOGY
- Subclinical tuberculosis disease - a review and analysis of prevalence surveys to inform definitions, burden, associations and screening methodology
- (2020) Beatrice Frascella et al. CLINICAL INFECTIOUS DISEASES
- Investigating Non-sterilizing Cure in TB Patients at the End of Successful Anti-TB Therapy
- (2020) Caroline G. G. Beltran et al. Frontiers in Cellular and Infection Microbiology
- The Pathogenesis of Tuberculosis–The Koch Phenomenon Reinstated
- (2020) Robert L. Hunter Pathogens
- Age-targeted tuberculosis vaccination in China and implications for vaccine development: a modelling study
- (2019) Rebecca C Harris et al. Lancet Global Health
- Constructing care cascades for active tuberculosis: A strategy for program monitoring and identifying gaps in quality of care
- (2019) Ramnath Subbaraman et al. PLOS MEDICINE
- One Month of Rifapentine plus Isoniazid to Prevent HIV-Related Tuberculosis
- (2019) Susan Swindells et al. NEW ENGLAND JOURNAL OF MEDICINE
- Spatial Network Mapping of Pulmonary Multidrug-Resistant Tuberculosis Cavities Using RNA Sequencing
- (2019) Keertan Dheda et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- IL-26 contributes to host defense against intracellular bacteria
- (2019) Angeline Tilly Dang et al. JOURNAL OF CLINICAL INVESTIGATION
- A Novel, High-sensitivity, Bacteriophage-based Assay Identifies Low-level Mycobacterium tuberculosis Bacteremia in Immunocompetent Patients With Active and Incipient Tuberculosis
- (2019) Raman Verma et al. CLINICAL INFECTIOUS DISEASES
- SHERLOCK: nucleic acid detection with CRISPR nucleases
- (2019) Max J. Kellner et al. Nature Protocols
- Reactive nitrogen species in host–bacterial interactions
- (2019) Ferric C Fang et al. CURRENT OPINION IN IMMUNOLOGY
- The mycobacterial cell envelope — a moving target
- (2019) Charles L. Dulberger et al. NATURE REVIEWS MICROBIOLOGY
- Is Mycobacterium tuberculosis infection life long?
- (2019) Marcel A Behr et al. BMJ-British Medical Journal
- Type I interferon-driven susceptibility to Mycobacterium tuberculosis is mediated by IL-1Ra
- (2019) Daisy X. Ji et al. Nature Microbiology
- Final Analysis of a Trial of M72/AS01E Vaccine to Prevent Tuberculosis
- (2019) Dereck R. Tait et al. NEW ENGLAND JOURNAL OF MEDICINE
- The Formation and Function of Granulomas
- (2018) Antonio J. Pagán et al. Annual Review of Immunology
- Incipient and Subclinical Tuberculosis: a Clinical Review of Early Stages and Progression of Infection
- (2018) Paul K. Drain et al. CLINICAL MICROBIOLOGY REVIEWS
- Genetics of human susceptibility to active and latent tuberculosis: present knowledge and future perspectives
- (2018) Laurent Abel et al. LANCET INFECTIOUS DISEASES
- Household-Contact Investigation for Detection of Tuberculosis in Vietnam
- (2018) Greg J. Fox et al. NEW ENGLAND JOURNAL OF MEDICINE
- Prevention of M. tuberculosis Infection with H4:IC31 Vaccine or BCG Revaccination
- (2018) Elisa Nemes et al. NEW ENGLAND JOURNAL OF MEDICINE
- Field-deployable viral diagnostics using CRISPR-Cas13
- (2018) Cameron Myhrvold et al. SCIENCE
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- (2018) Janice S. Chen et al. SCIENCE
- Multiplexed and portable nucleic acid detection platform with Cas13, Cas12a, and Csm6
- (2018) Jonathan S. Gootenberg et al. SCIENCE
- Phase 2b Controlled Trial of M72/AS01E Vaccine to Prevent Tuberculosis
- (2018) Olivier Van Der Meeren et al. NEW ENGLAND JOURNAL OF MEDICINE
- Revisiting the timetable of tuberculosis
- (2018) Marcel A Behr et al. BMJ-British Medical Journal
- Improved treatment completion with shorter treatment regimens for latent tuberculous infection
- (2018) M. M. Macaraig et al. INTERNATIONAL JOURNAL OF TUBERCULOSIS AND LUNG DISEASE
- The value of transcriptomics in advancing knowledge of the immune response and diagnosis in tuberculosis
- (2018) Akul Singhania et al. NATURE IMMUNOLOGY
- Vitamin D Supplements and Prevention of Cancer and Cardiovascular Disease
- (2018) JoAnn E. Manson et al. NEW ENGLAND JOURNAL OF MEDICINE
- Concurrent infection with Mycobacterium tuberculosis confers robust protection against secondary infection in macaques
- (2018) Anthony M. Cadena et al. PLoS Pathogens
- Accuracy of line probe assays for the diagnosis of pulmonary and multidrug-resistant tuberculosis: a systematic review and meta-analysis
- (2017) Ruvandhi R. Nathavitharana et al. EUROPEAN RESPIRATORY JOURNAL
- MTBVAC from discovery to clinical trials in tuberculosis-endemic countries
- (2017) Dessislava Marinova et al. Expert Review of Vaccines
- Tuberculosis Outbreaks in the United States, 2009-2015
- (2017) Godwin Mindra et al. PUBLIC HEALTH REPORTS
- Host blood RNA signatures predict the outcome of tuberculosis treatment
- (2017) Ethan G. Thompson et al. TUBERCULOSIS
- Digitally Barcoding Mycobacterium tuberculosis Reveals In Vivo Infection Dynamics in the Macaque Model of Tuberculosis
- (2017) Constance J. Martin et al. mBio
- Origins of Combination Therapy for Tuberculosis: Lessons for Future Antimicrobial Development and Application
- (2017) Christopher A. Kerantzas et al. mBio
- Intracellular growth of Mycobacterium tuberculosis after macrophage cell death leads to serial killing of host cells
- (2017) Deeqa Mahamed et al. eLife
- New Insights in to the Intrinsic and Acquired Drug Resistance Mechanisms in Mycobacteria
- (2017) Mohammad J. Nasiri et al. Frontiers in Microbiology
- A blood RNA signature for tuberculosis disease risk: a prospective cohort study
- (2016) Daniel E Zak et al. LANCET
- Inflammatory signaling in human tuberculosis granulomas is spatially organized
- (2016) Mohlopheni J Marakalala et al. NATURE MEDICINE
- PET CT Identifies Reactivation Risk in Cynomolgus Macaques with Latent M. tuberculosis
- (2016) Philana Ling Lin et al. PLoS Pathogens
- Prevalence of tuberculosis in post-mortem studies of HIV-infected adults and children in resource-limited settings
- (2015) Rishi K. Gupta et al. AIDS
- The human immune response to tuberculosis and its treatment: a view from the blood
- (2015) Jacqueline M. Cliff et al. IMMUNOLOGICAL REVIEWS
- Heterogeneity in tuberculosis pathology, microenvironments and therapeutic responses
- (2015) Anne Lenaerts et al. IMMUNOLOGICAL REVIEWS
- Human tuberculosis predates domestication in ancient Syria
- (2015) Oussama Baker et al. TUBERCULOSIS
- Variability in Tuberculosis Granuloma T Cell Responses Exists, but a Balance of Pro- and Anti-inflammatory Cytokines Is Associated with Sterilization
- (2015) Hannah Priyadarshini Gideon et al. PLoS Pathogens
- Type I IFN Induces IL-10 Production in an IL-27–Independent Manner and Blocks Responsiveness to IFN-γ for Production of IL-12 and Bacterial Killing inMycobacterium tuberculosis–Infected Macrophages
- (2014) Finlay W. McNab et al. JOURNAL OF IMMUNOLOGY
- Host-directed therapy of tuberculosis based on interleukin-1 and type I interferon crosstalk
- (2014) Katrin D. Mayer-Barber et al. NATURE
- PET/CT imaging correlates with treatment outcome in patients with multidrug-resistant tuberculosis
- (2014) R. Y. Chen et al. Science Translational Medicine
- Effect of BCG vaccination against Mycobacterium tuberculosis infection in children: systematic review and meta-analysis
- (2014) A. Roy et al. BMJ-British Medical Journal
- The Immune Response in Tuberculosis
- (2013) Anne O'Garra et al. Annual Review of Immunology
- Protection by BCG Vaccine Against Tuberculosis: A Systematic Review of Randomized Controlled Trials
- (2013) Punam Mangtani et al. CLINICAL INFECTIOUS DISEASES
- Palaeopathology and genes: Investigating the genetics of infectious diseases in excavated human skeletal remains and mummies from past populations
- (2013) Evilena Anastasiou et al. GENE
- Out-of-Africa migration and Neolithic coexpansion of Mycobacterium tuberculosis with modern humans
- (2013) Iñaki Comas et al. NATURE GENETICS
- Sterilization of granulomas is common in active and latent tuberculosis despite within-host variability in bacterial killing
- (2013) Philana Ling Lin et al. NATURE MEDICINE
- Type I Interferon Suppresses Type II Interferon-Triggered Human Anti-Mycobacterial Responses
- (2013) R. M. B. Teles et al. SCIENCE
- TB or Not TB: That Is No Longer the Question
- (2013) R. L. Modlin et al. Science Translational Medicine
- CD4 T Cell Depletion Exacerbates Acute Mycobacterium tuberculosis While Reactivation of Latent Infection Is Dependent on Severity of Tissue Depletion in Cynomolgus Macaques
- (2012) Philana Ling Lin et al. AIDS RESEARCH AND HUMAN RETROVIRUSES
- Risk of Progression to Active Tuberculosis Following Reinfection With Mycobacterium tuberculosis
- (2012) Jason R. Andrews et al. CLINICAL INFECTIOUS DISEASES
- Distinct Phases of Blood Gene Expression Pattern Through Tuberculosis Treatment Reflect Modulation of the Humoral Immune Response
- (2012) Jacqueline M. Cliff et al. JOURNAL OF INFECTIOUS DISEASES
- Detectable Changes in The Blood Transcriptome Are Present after Two Weeks of Antituberculosis Therapy
- (2012) Chloe I. Bloom et al. PLoS One
- An In Vivo Platform for Rapid High-Throughput Antitubercular Drug Discovery
- (2012) Kevin Takaki et al. Cell Reports
- Tuberculosis and HIV Co-Infection
- (2012) Andrzej Pawlowski et al. PLoS Pathogens
- Predictive value of interferon-γ release assays for incident active tuberculosis: a systematic review and meta-analysis
- (2011) Molebogeng X Rangaka et al. LANCET INFECTIOUS DISEASES
- Use of whole genome sequencing to estimate the mutation rate of Mycobacterium tuberculosis during latent infection
- (2011) Christopher B Ford et al. NATURE GENETICS
- Vitamin D Is Required for IFN- -Mediated Antimicrobial Activity of Human Macrophages
- (2011) M. Fabri et al. Science Translational Medicine
- Evidence for waning of latency in a cohort study of tuberculosis
- (2010) Harald G Wiker et al. BMC INFECTIOUS DISEASES
- An interferon-inducible neutrophil-driven blood transcriptional signature in human tuberculosis
- (2010) Matthew P. R. Berry et al. NATURE
- Spectrum of latent tuberculosis — existing tests cannot resolve the underlying phenotypes
- (2010) Madhukar Pai NATURE REVIEWS MICROBIOLOGY
- Rapid Molecular Detection of Tuberculosis and Rifampin Resistance
- (2010) Catharina C. Boehme et al. NEW ENGLAND JOURNAL OF MEDICINE
- Granuloma Encapsulation Is a Key Factor for Containing Tuberculosis Infection in Minipigs
- (2010) Olga Gil et al. PLoS One
- Mycobacterial outer membranes: in search of proteins
- (2010) Michael Niederweis et al. TRENDS IN MICROBIOLOGY
- Cell-Mediated Immune Responses in Tuberculosis
- (2009) Andrea M. Cooper Annual Review of Immunology
- The spectrum of latent tuberculosis: rethinking the biology and intervention strategies
- (2009) Clifton E. Barry et al. NATURE REVIEWS MICROBIOLOGY
- A Critical Role for CD8 T Cells in a Nonhuman Primate Model of Tuberculosis
- (2009) Crystal Y. Chen et al. PLoS Pathogens
- Potential of Mw as a prophylactic vaccine against pulmonary tuberculosis
- (2008) K. Katoch et al. VACCINE
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