The immunoregulatory landscape of human tuberculosis granulomas

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TGFβ restricts expansion, survival, and function of T cells within the tuberculous granuloma

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Anti-PD-1 immunotherapy leads to tuberculosis reactivation via dysregulation of TNF-α

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Tryptophan catabolism reflects disease activity in human tuberculosis

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Spatial and temporal localization of immune transcripts defines hallmarks and diversity in the tuberculosis granuloma

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Host-response-based gene signatures for tuberculosis diagnosis: A systematic comparison of 16 signatures

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Neutrophils express pro- and anti-inflammatory cytokines in granulomas from Mycobacterium tuberculosis-infected cynomolgus macaques

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Reactivation of tuberculosis in cancer patients following administration of immune checkpoint inhibitors: current evidence and clinical practice recommendations

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IL-10 Impairs Local Immune Response in Lung Granulomas and Lymph Nodes during Early Mycobacterium tuberculosis Infection

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Limited Antimycobacterial Efficacy of Epitope Peptide Administration Despite Enhanced Antigen-Specific CD4 T-Cell Activation

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Implications of Tuberculosis Reactivation after Immune Checkpoint Inhibition

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A Structured Tumor-Immune Microenvironment in Triple Negative Breast Cancer Revealed by Multiplexed Ion Beam Imaging

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Alveolar Macrophages Provide an Early Mycobacterium tuberculosis Niche and Initiate Dissemination

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PD-1 Controls Follicular T Helper Cell Positioning and Function

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A multi-cohort study of the immune factors associated with M. tuberculosis infection outcomes

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MetaCyto: A Tool for Automated Meta-analysis of Mass and Flow Cytometry Data

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Defective positioning in granulomas but not lung-homing limits CD4 T-cell interactions with Mycobacterium tuberculosis-infected macrophages in rhesus macaques

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In vivo inhibition of tryptophan catabolism reorganizes the tuberculoma and augments immune-mediated control ofMycobacterium tuberculosis

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Digitally Barcoding Mycobacterium tuberculosis Reveals In Vivo Infection Dynamics in the Macaque Model of Tuberculosis

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Sequential inflammatory processes define human progression from M. tuberculosis infection to tuberculosis disease

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A blood RNA signature for tuberculosis disease risk: a prospective cohort study

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Persisting positron emission tomography lesion activity and Mycobacterium tuberculosis mRNA after tuberculosis cure

(2016) Stephanus T Malherbe et al.   NATURE MEDICINE

Inflammatory signaling in human tuberculosis granulomas is spatially organized

(2016) Mohlopheni J Marakalala et al.   NATURE MEDICINE

Methods to increase reproducibility in differential gene expression via meta-analysis

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Induced Regulatory T Cells: Their Development, Stability, and Applications

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IDO in the Tumor Microenvironment: Inflammation, Counter-Regulation, and Tolerance

(2016) David H. Munn et al.   TRENDS IN IMMUNOLOGY

Deep Learning Automates the Quantitative Analysis of Individual Cells in Live-Cell Imaging Experiments

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Does pharmacist-supervised intervention through pharmaceutical care program influence direct healthcare cost burden of newly diagnosed diabetics in a tertiary care teaching hospital in Nepal: a non-clinical randomised controlled trial approach

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Mycobacterium tuberculosis exploits the formation of new blood vessels for its dissemination

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FlowSOM: Using self-organizing maps for visualization and interpretation of cytometry data

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Lesion-Specific Immune Response in Granulomas of Patients with Pulmonary Tuberculosis: A Pilot Study

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Cellular dynamics of resolving inflammation

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Early Changes by 18Fluorodeoxyglucose Positron Emission Tomography Coregistered with Computed Tomography Predict Outcome after Mycobacterium tuberculosis Infection in Cynomolgus Macaques

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Programmed Death (PD)-1:PD-Ligand 1/PD-Ligand 2 Pathway Inhibits T Cell Effector Functions during Human Tuberculosis

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Interception of host angiogenic signalling limits mycobacterial growth

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Sterilization of granulomas is common in active and latent tuberculosis despite within-host variability in bacterial killing

(2013) Philana Ling Lin et al.   NATURE MEDICINE

Granuloma Correlates of Protection Against Tuberculosis and Mechanisms of Immune Modulation by Mycobacterium tuberculosis

(2012) Smriti Mehra et al.   JOURNAL OF INFECTIOUS DISEASES

Common patterns and disease-related signatures in tuberculosis and sarcoidosis

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Sarcoidosis Blood Transcriptome Reflects Lung Inflammation and Overlaps with Tuberculosis

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Programmed death ligand 1 is over-expressed by neutrophils in the blood of patients with active tuberculosis

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CD4+Regulatory T Cells in a Cynomolgus Macaque Model ofMycobacterium tuberculosisInfection

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An interferon-inducible neutrophil-driven blood transcriptional signature in human tuberculosis

(2010) Matthew P. R. Berry et al.   NATURE

Sarcoidosis is a Th1/Th17 multisystem disorder

(2010) M. Facco et al.   THORAX

The mechanisms and consequences of the extra-pulmonary dissemination of Mycobacterium tuberculosis

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Who Benefits from Granulomas, Mycobacteria or Host?

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The Role of the Granuloma in Expansion and Dissemination of Early Tuberculous Infection

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